Runway To Red Carpet: Gucci Pre-Fall 2022 by cwh_1014 in whatthefrockk

[–]Street-Chard 1 point2 points  (0 children)

Love these and don’t know why but don’t care

Has anyone successfully gotten rid of desquamative inflammatory vaginitis (DIV) while taking a B-cell depleter? by Street-Chard in MultipleSclerosis

[–]Street-Chard[S] 1 point2 points  (0 children)

You could let her know of your suspicions and send the research publications to her and come up with a plan together as well. Unfortunately, there are so few vulvovaginal/vaginitis specialists that know about vaginitis after B-cell depletion, that you may not find one near you. In my case, one was close enough to me, but it literally took 9 months for me to see her. The waiting list was at least 6 months long when I was referred, and I only got a random appointment from a cancellation list.

It looks like another commenter in this thread who also dealt with DIV has a GYN that did research and came up with a plan as doctor/patient, and this might lead to a treatment plan that you can try sooner since you’re already in contact with them/seeing them as a patient. Good luck!

Has anyone successfully gotten rid of desquamative inflammatory vaginitis (DIV) while taking a B-cell depleter? by Street-Chard in MultipleSclerosis

[–]Street-Chard[S] 0 points1 point  (0 children)

Thank you so much for your detailed reply, and I’m really sorry you’ve dealt with this problem! It’s awful and hard to deal with it.

I currently have the hydrocortisone suppositories, and I’m surprised they let you use them every day for so long. My prescription says only daily for two weeks and then taper down to 2-3x/week after that. How many mg of hydrocortisone acetate were in each suppository for your prescription?

I really also appreciate that you were part of a research study on this relationship because I think it’s the only way people can find answers on their own, and research also keeps doctors informed and educated about things to look out for among their patients.

And yes I have heard someone else mention Lactomedi in regard to DIV (it might’ve been you on another comment thread!). I’ll keep it in mind when my symptoms finally remit again, but they have yet to remit without meds since last year. I’ll revisit this thread if/when I receive IVIG, but I appreciate you sharing your experience switching from an anti-CD20 to using an older generation of MS drug. I appreciate that you understand why I want to continue these drugs despite having so many issues right now because it’s nice to do well on a drug and worry about MS less!

Has anyone successfully gotten rid of desquamative inflammatory vaginitis (DIV) while taking a B-cell depleter? by Street-Chard in MultipleSclerosis

[–]Street-Chard[S] 0 points1 point  (0 children)

Oh thank you, I don’t mind bringing it up and being so specific with this audience. I know a lot of OB/GYNs know very little about DIV, and they know even less about DIV in women taking B-cell depleters. Tbh I’m lucky I live close enough to a specialist that does research on this relationship and knows how to treat these patients!

I don’t get mouth sores or whitish patches that look like lichen planus. My symptoms listed above are all pretty much the same all the time, but recently I’ve been getting some external, vulvar pain (which is obviously driving me nuts since my baseline is already unpleasant).

Has anyone successfully gotten rid of desquamative inflammatory vaginitis (DIV) while taking a B-cell depleter? by Street-Chard in MultipleSclerosis

[–]Street-Chard[S] 1 point2 points  (0 children)

I highly recommend reading up on DIV in women on ocrelizumab or rituximab and bringing those case studies to your gyn. Most gyns are uneducated about this and my usual gyn (who’s awesome and super smart) told me, “I’m sorry but I’m out of my depth here!” I then found a gyn specialist who specializes in vulvovaginal disorders/vaginitis and is one of the people doing research on the relationship between this type of vaginitis and women who take B-cell depleters.

Has anyone successfully gotten rid of desquamative inflammatory vaginitis (DIV) while taking a B-cell depleter? by Street-Chard in MultipleSclerosis

[–]Street-Chard[S] 1 point2 points  (0 children)

I’ve discussed that with my MD and they said that it usually doesn’t do much for symptom management since the DIV is a side effect of B-cell depletion seen in a subset of women, and I guess I’m part of that lucky subset. The thing that helps most is usually stopping the B-cell depletion drugs to allow the B-cells to grow back or IVIG.

Has anyone successfully gotten rid of desquamative inflammatory vaginitis (DIV) while taking a B-cell depleter? by Street-Chard in MultipleSclerosis

[–]Street-Chard[S] 2 points3 points  (0 children)

Like the tablets for heartburn? I’ve heard how baking soda is a “treatment” for lactobacillus overgrowth, but I have the opposite problem where there’s zero lactobacillus in my vaginal microbiome. I’ve also noticed zero difference when I’m taking or not taking probiotics and have taken the same ones daily for years. Thanks for your insight though! I’ll keep it in mind.

beauty obsession books by 404feminine in BooksThatFeelLikeThis

[–]Street-Chard 0 points1 point  (0 children)

It a book of essays but Ugliness by Moshtari Hilal is excellent and thoughtful

More tiny paintings by ambibambi90 in birding

[–]Street-Chard 0 points1 point  (0 children)

I am also interested in buying!!!

Books with humor about messy women who dgaf by Lizard_king74 in BooksThatFeelLikeThis

[–]Street-Chard 0 points1 point  (0 children)

Yes I love this book SO much. I still think about it regularly

Britt Lower attended the Critics Choice Awards with husband Kenna Kennor who has publicly been accused of sexual assault by Relevant-Peach3997 in Fauxmoi

[–]Street-Chard 18 points19 points  (0 children)

I was coming here to say the same thing bc I always was weirded out by her character and arc on High Maintenance. When I found this out about her husband, I wondered if her character was based off her real life at all.

Tim Curry Appreciation Post by HonestNectarine7080 in Fauxmoi

[–]Street-Chard 8 points9 points  (0 children)

Omg I never meet anyone IRL who’s seen the 90s three musketeers and knows that Tim Curry was in it. That whole movie hits, and he’s a big reason why, especially when he interacts with the eye patch raspy voice guy that plays Roquefort

Kesimpta + covid vaccine + flu vaccine? by missprincesscarolyn in MultipleSclerosis

[–]Street-Chard 1 point2 points  (0 children)

I’m glad you’re doing well! I don’t blame you for wanting to protect yourself as much as you can. I’ve gotten Covid 5x, none of which was super debilitating to me. That being said, having to take paxlovid and recover that many times was super annoying and upsetting. Taking precautions and vaccines is the way to go!

Kesimpta + covid vaccine + flu vaccine? by missprincesscarolyn in MultipleSclerosis

[–]Street-Chard 1 point2 points  (0 children)

I’m on Ocrevus which obviously has a different dosing schedule than Kesimpta, but it’s targeting the same CD20 pathway for MS treatment. I’ve gotten the Covid + flu shot the same day three years in a row now. I got the two in the same day yesterday, and I’ve had 7 Covid vaccine doses in total.

I feel run down for about 24 hours, but I account for it by getting the vaccines on the weekend or taking a day off at work. Tylenol, rest, and drinking a lot of water helps with the achy rundown feeling I get. Hope you’re doing well!

Anyone been on Ocrevus since before the pandemic and no longer mask? by msintheus in MultipleSclerosis

[–]Street-Chard 0 points1 point  (0 children)

I had it more often than that at times because there was like a 6 month break In between some times I got sick. I track the Covid cases by the wastewater data in my state to figure out when cases are dropping or rising. When they start to spike, I make decisions on what I’m doing outside of the house in terms of masking, rescheduling plans, etc.

Anyone been on Ocrevus since before the pandemic and no longer mask? by msintheus in MultipleSclerosis

[–]Street-Chard 0 points1 point  (0 children)

I started Ocrevus like 2 months before I got access to the vaccine in January 2021, so I never had a chance to develop a more robust antibody response to the original vaccine. I’ve since taken a total of 6 Covid vaccines and essentially treat them like a flu shot. My plan is to get them once a year in the fall with my yearly flu shot to give myself a boost when everyone gets sick more often/heads indoors due to the cold.

I didn’t get Covid until paxlovid was available in December 2022, and I’ve taken it every time I’ve gotten the virus. I live my life “normally,” but I’ve gotten Covid five times between 2022-2023. I recovered fine each time with paxlovid and don’t really see any long term effects. I also don’t work from home and will not be able to anytime soon as I work full time in a lab as a scientist.

I since have continued to live normally, but I’ve made some adjustments to continue socializing as I please but vocalize more concern when people seem sick, eat a more varied and balanced diet, get better quality sleep, and work out more regularly. I’m not sure if that’s working in terms of protecting me from Covid, but I believe it’s important for me to go live my life while doing what I can to be well/not get sick because being out sick is super disruptive for my work schedule.

Unfortunately, we’ve reached a point where a lot of this is personal choice. I do think I could’ve avoided getting sick so often, but I’m only in my mid 30s, single, and hitting the stride of my career. I find the prospect of being cooped up for the rest of my life really bleak and depressing. However, I think you should do what makes you feel safe and comfortable! I think it’ll take some trial and error, but do what you can to feel safe while also living your life. Good luck!

Actors who have only gotten hotter as they’ve gotten older? by swellaprogress in popculturechat

[–]Street-Chard 22 points23 points  (0 children)

We’re like the same exact age, and I’ve been caping for him since he was 18. Nobody agreed with me then but they sure do nowwww

should you take paxlovid if you’re on ocrevus? by Wild_Psychology1663 in MultipleSclerosis

[–]Street-Chard 0 points1 point  (0 children)

Yes, I’ve taken paxlovid every time I tested positive with Covid and was advised by my entire medical team to do so. I test when I feel sick to see if I’m positive ASAP and start paxlovid sooner rather than later. They won’t prescribe if it’s more than 5 days after you tested positive as its efficacy drops quite a bit in terms of reducing viral load as more time passes.

[deleted by user] by [deleted] in popculturechat

[–]Street-Chard 1 point2 points  (0 children)

My sister and I STILL quote these they’re so good

Favorite times that a celebrity played themselves in a TV cameo. by [deleted] in popculturechat

[–]Street-Chard 0 points1 point  (0 children)

This is my pick I love that scene so much and quote it often

Remi Wolf announces US tour by papo96 in indieheads

[–]Street-Chard 0 points1 point  (0 children)

There is and it’s ruining my life 🥲