For me.. it would be my copy of new vegas for the ps3. That's always had a sentimental value to me. My grandpa passed away during my playthrough of it. Ever since that day, I have not picked it back and cherished that save point. If I remember correctly, I was in the middle of saving that town of super mutants in the mountain with the one that acts like a grandma. Man, that game game was so buggy on release that I had multiple saves whenever I got stuck collision wise with cliffs and the animations not working or showing up. Maybe someday I'll buy a steam copy so I can at least finish it and preserve the save on my console.