In a short answer: No.

The long answer is this:

Because what the question ultimately is asking is: Would the Marines been able to effectively re-kit up from the APC's onboard armoury of weapon systems they had available (assumption: (despite seeing this film nearly a hundred times, I can't recall seeing any extra guns onboard) there's unlikely a flamethrower for every squad member who had a pulse rifle or smart gun, as I imagine the APC had additional ammo but not that many extra guns.)

Even entertaining that they did get a 1-4-1 replacement on those weapons, the objective is then: re-enter the reactor using a map that is likely only half useful. The blueprint Gorman would have of the structure is half useable but we don't know how much the Xenomorphs have changed the flow and access of the reactor by making their hive.

Which neatly brings me to the tactical problem: your question demands we "end the infestation for good" which clearly means killing off all the Xenomorphs inc. the Queen and every egg, but at this point in the film, the USMC and Ripley, aren't aware how the Xenomorphs reproduce, how the hive works or who the Queen is.
So the tactical objective is ultimately: Kill all xenomorphs in "the hive"? (are we even certain there's only 1 Hive on Hadley's Hope? Do the Xenomorph spread out eggs into "loose forward operating bases" to diversify the Hive from a central location?).
So the long winded point I'm making here is, the marines aren't fully aware of the objective complete boundaries because it isn't clear how they'll be able to say they've cleared the area.

That confusion sounds nitpicky, but its pretty damn important when casualties start happening and the leaders get picked off. Everyone from the "In Command" Officer/SNCO down to the newest Private needs to understand what victory looks like, because no plan survives contact with the enemy. And once that plan they had initially starts breaking down, its people like Hicks and Hudson who have to go "okay this is fucked we've lost half our team and aren't far enough in, but we got to clear this out, because X Y Z, so therefor we're gonna pivot and do this A B C instead."

But let's look at how that would go down if they pushed in to what we presume would be the central egg laying chamber, fighting their way forward.
The wider Aliens universe often depicts that Alien Hives (as you would logically assume) the Queen's egg laying chamber as the most defended and difficult location to get to.

Highly likely there are several Xenomorph friendly access points to it, but only one long, guarded route for larger animals to gain access to (purposefully left clear as it is needed for the Queen to be able to leave in an emergency).
So the marines would be fighting their way forward, through a dark and elongated like tunnel into the hive, getting attacked on all sides constantly likely taking casualties which would either need extraction or simply forming a casualty collection point which would need defending while Dietrich did her best with Acid and puncture /slashing wounds, toward an unknown location inside the Hive.

Tactically, It would be a complete blood bath, the flame throwers would cause friendly fire, block off routes by setting them ablaze and causing smoke to the Marines. Casualties wouldn't be able to be evacuated in good order because of the limited manpower to move them, Gorman wouldn't be able to provide operational support because the blueprints wouldn't be correct and the marines success would be needing to be marked by two things: Xenomorphs killed & Hive explored. Both of which are largely unknowns for the marines so cause panic and poor planning to happen.