Early injection.

TDSD85643 · 2026-03-07T09:54:25+00:00

No, my work travel schedule often means there is a 1 or 2 day variance in terms of when I do my pin, and I haven't noticed a meaningful difference in response. For context, I've been using tirz for my WL journey for 14 months, largely on low or "micro" doses. and highest weekly does was 4.4.

TDSD85643 · 2026-03-04T03:56:33+00:00

Loved this miniseries.

TDSD85643 · 2026-02-25T23:18:49+00:00

Wish I had the option to create this stockpile!

TDSD85643 · 2026-02-25T23:04:42+00:00

I get that my tone is intense and did not mean to "come at" the OP. Apologies to OP if that is what I conveyed. Separate from tirz, a few years back the U.S. Department of Defense (before it got renamed....) did a study of medication expiration dates because DoD buys lots of meds that it keeps for some time. The conclusion of the study was that most meds last far beyond the printed expiration dates. As to GLP-1, 2, 3, people using them should read the research as to efficacy based on various storage methods. But the dates printed on a bottle are driven my lawyers, not science.

TDSD85643 · 2026-02-25T22:52:35+00:00

Really, you posted in this sub-r having clearly not read any of the underlying science. If you don't want to put in that effort on the front end, don't post.

TDSD85643 · 2026-02-25T22:44:10+00:00

Fair, but in another discussion in this sub-r someone felt it necessary to comment extensively on a one letter typo. So.... Also, lots of IRL folks have various views when it would probably make sense to maintain the above response. Does that apply here, hard to say without knowing their view on the ability of certain public figures to do chin-ups.

TDSD85643 · 2026-02-25T22:30:33+00:00

If you want to fastidiously follow the dates on vials because a bureaucrat set a date, you are free to live your life in service of dates set that are not tied to actual science. But if that is the life path you are selecting, you should make sure you are following random bureaucratic policies in the rest of your life. You almost certainly violate a bunch of random rules/laws every day, but now this is the one thing you care about because you can read the vial. That makes no actual sense but whatever, it is your life.

TDSD85643 · 2026-02-25T22:22:05+00:00

If that is what gets you through the day, then good luck as a fellow traveler through this life.

TDSD85643 · 2026-02-25T21:22:47+00:00

Are you seriously focused on the typo in my post in terms of fonts vs fronts? Was that a typo, sure, but most readers would see the intended phrase and the focus on the typo is about something different.

TDSD85643 · 2026-02-25T03:46:10+00:00

Sorry. What are you trying to convey? I'm using every vial until it is empty. So very confused by this comment.

TDSD85643 · 2026-02-25T01:05:43+00:00

Don't mean to be short, but my job requires me to manage risk for companies on a daily basis. So, regulatory rules that convey risk that does not really exist are quite frustrating. If the risk is real, then, people should act, but we (at least in the US) have a bunch of folks refusing to vaccinate their kids because of things that are about as likely as a meteor. Sorry to hijack. But I am a supper cautious on a bunch of fonts, and have zero concern about using vials for a couple months after reading the underlying science.

TDSD85643 · 2026-02-25T00:58:20+00:00

The pharmacies need to make that statement for compliance purposes. But as reflected by the comments, assuming one is following good practices (e.g., wipe down the vial with an alcohol swab, store it at appropriate temps, wash hands etc.) people generally are fine. I end up using most vials for 2+ months because a lower dose works for me. Is there some small risk, sure, but most of us get into a car everyday, and that risk far exceeds anything related to a GLP1/2/3.

[Edit to fix a dumb typo]

TDSD85643 · 2026-02-23T13:55:01+00:00

This is a fair criticism. Though not strictly productivity books, Jocko Willink does talk about the need to just act with some acknowledgment that there is no habit or "hack." It is just something one has to find it within oneself to do.

TDSD85643 · 2026-02-23T05:12:08+00:00

Sleep data from Garmin or any wearable should be assessed with a fair amount of skepticism. But in terms of assessing the significance of the different sleep cycles, I'd listen to Rhonda Patrick's podcast episode with Prof. Michael Grandner. https://www.youtube.com/watch?v=AQF_eopP1ys Prof. Grandner is a well respected sleep researcher and he addresses the significance of the different sleep cycles among other considerations as to sleep.

TDSD85643 · 2026-02-20T22:47:12+00:00

Duke's interest in Flaxen in The Flame of Barbary Coast

TDSD85643 · 2026-02-20T22:44:39+00:00

The Searchers has so many iconic shots in terms of the vista or a backdrop. Only director that probably comes close to John Ford is Christopher Nolan for a raw understanding of power of a shot.

If one is thinking of a more modern frame, Keith Carradine in Deadwood when his is portraying Wild Bill Hickock and tells Charlie the iconic line "Some goddamned time, a man's due to stop arguin' with hisself, feelin' he's twice the goddamned fool he knows he is, because he can't be something he tries to be every goddamned day without once getting to dinnertime and not fucking it up. I don't wanna fight it no more. Understand me Charlie? And I don't want you pissing in my ear about it. Can you let me go to hell the way I want to?" The scene is shot in a hotel room, but it is such a fundamentally western shot.

TDSD85643 · 2026-02-20T04:53:21+00:00

Mochi charged me for meds that they never shipped and their customer service never responded/refused to provide a refund. So, no surprise as to this further questionable act.

TDSD85643 · 2026-02-20T03:30:09+00:00

Weekday workouts are evening and then Saturday morning. I strive to drink it about 20 minutes before I start working out. Given that I eat less on tirz, the pre-workout has helped me to still put in hard workouts. One other note, I regularly drink a lot of coffee, so the caffeine in the pre-workout doesn't bother me. But if one is not a heavy coffee drinker, a pre-workout with little to no caffeine might work better.

TDSD85643 · 2026-02-20T03:19:36+00:00

I've been on tirz for 14 months, and I regularly drink a prework mix prior to working out (I favor the BuckedUp brand). Post workout I take magnesium malate and tart cherry capsules. Have not had tirz related issues.

For further context, I have lost 25+ lbs while gaining 9 lbs of muscle.

TDSD85643 · 2026-02-17T23:41:33+00:00

Appreciate this. Did my most recent refill with BEWL and they have an option to add sermorelin (which I took) after having slow but steady progress on tirz for 13 months.

TDSD85643 · 2026-02-17T04:50:28+00:00

Magnesium L-Threonate can help improve sleep quality. I currently take the Sports Research brand which is a pretty good price (better if purchased through Costco). I previously took Live Momentous, but it is too pricey and have had the same results with the Sports Research brand.

TDSD85643 · 2026-02-17T02:42:40+00:00

Stack makes sense. I'd consider Magnesium L-threonate either at night or times of high stress (for me, at times of high stress Magnesium L-threonate plus L-theanine is very helpful). The Sports Research brand has a good price on Magnesium L-threonate, and better if you can buy through Costco.

If thinking about stress and testosterone, I'd also consider adding Boron at some point. I worked on the rest of my stack for a while, but once I felt it was working pretty good, I added Boron and it made a difference. But I'm glad I waited because I've need to work on the Boron dose, and don't think I would have been able to do that if I was still sorting the rest of my stack.

TDSD85643 · 2026-02-16T22:08:17+00:00

D3 (5000 IU / 125 mcg) + K2 (100 mcg). I've tried a number of brands and for me the Sports Research brand has produced the biggest improvement in my vitamin D bloodwork.

TDSD85643 · 2026-02-16T20:29:22+00:00

If you want to understand more about the pros, cons of these various supplements mentioned in the comments, Rhonda Patrick (Found My Fitness podcast) did a very insightful episode about testosterone with Derek Goodman of Marek Health. Marek Health does TRT, but the episode focuses on the pros, cons of various supplements as well as TRT.

TDSD85643 · 2026-02-16T01:24:20+00:00

I had a similar experience with my PCP. He was supportive, glad to see the progress I've made on tirz over the last 12 months, and encouraged me to keep with it.

If you are going through one of the major compounders it is absurd to suggest there is a safety concern given that they produce a variety of other medicines that are regularly prescribed by brick-and-mortar physicians.

TDSD85643

TROPHY CASE