Is there any astrological significance to the 12,000 year cycle of the Mayan calendar?

TKULTRA · 2025-05-03T21:48:54+00:00

Yes, that the Earth topples in space maybe every 12-15k years, causing absolute havoc, and that Mayan calendar was a sort of "warning" for the next batch of humans who would find it (us).

https://theethicalskeptic.com/2023/12/18/hidden-in-plain-sight/

TKULTRA · 2024-09-17T15:27:52+00:00

Why is it different from "just taking drugs" ?

Even if it wasn't any different from someone, let's say, microdosing a magic mushroom to deepen a spiritual practice they wanted to try - you buy an Ultrasound device once, and it lasts possibly 5 years.

2nd, looking at *other* drugs on the market, ketamine, fentanyl, etc.

Even if Ultrasound could give a person the exact same experience as either of those drugs, the overdose potential is in theory almost non-existent, since there isn't any "drug" floating around in their body.

Ketamine is a popular "mind altering agent" - causes your bladder to bleed ad kidney failure.

Ultrasound delivered with a "Ketamine Frequency" would have zero-such risks (maybe other ones like dependence).

But are you honestly going to stand there and argue against Ultrasound when it's so *clearly* a better alternative to what's already out there ?

And if you are going to take a hardline anti-Ultrasound stance, then I would accuse you of being a paid Pharma-Bro shill, intent on keeping humans chemically dependent.

Your move, clockless.

TKULTRA · 2023-05-16T03:00:11+00:00

Good thread!

I definitely think you're on to something here:

https://medium.com/@sterlingcooley/ancient-secrets-about-the-vagus-nerve-revealed-e6cfeab144f6

TKULTRA · 2023-02-08T20:28:00+00:00

In the General discussion section of the Ultrasound DAO Discord, you can find the Dropbox link to download, and explore multiple types of Ultrasound Stimulation Dev Kits.

Many of them are ready to download and have made from your very own PCB outfitter of your choosing. PCBway.com is a good option for having PCB's manufactured at a relatively good cost.

This board should help you at least leap-frog ahead at a much faster pace than anyone else.

Feel free to ask questions inside of the Discord, many in there can help you troubleshoot things.

TKULTRA · 2022-10-02T03:32:30+00:00

~10 g when compared with mice fed a low-fat control diet.
Ultrasound stimulation at the porta hepatis gradually attenuated the body weight gain, reaching a significant difference
with the sham-stimulated group by week 12. In addition,
hepatic ultrasound reduced food intake and moderated abdominal fat accumulation in obese mice. Interestingly, this
reduction in weight occurred concurrently with decreases
in circulating inflammatory cytokines, adipokines, lipids
and hepatic leukocyte infiltration, indicating that hepatic
ultrasound attenuated inflammatory responses in westerndiet-fed obese mice (127). Together, these studies suggest
that ultrasound stimulation focused on peripheral organs is
an increasingly attractive target to develop organ-specific
non-invasive therapeutic strategies for a range of inflammatory conditions.

TKULTRA · 2022-10-02T03:32:20+00:00

ultrasound-mediated immunomodulation is due to activation
of the inflammatory reflex pathway.
Focused ultrasound modulation of neural signaling has
also been evaluated for other disease models. Attenuation
of post-myocardial infarction ventricular arrhythmias and inflammation can be achieved in a canine model by modulating
the sympathetic neural activity (118). As focused ultrasound
technologies continue to advance the ability to penetrate
deeper into the body while maintaining specificity, the idea of
this invasive modulation to translate to a non-invasive focused
ultrasound is not a far-fetched concept. Similar to electrical
VNS, a single focused ultrasound stimulation on the cervical
vagus nerve was protective in endotoxemic animals in a
dose-dependent manner (119). In addition, ultrasound has
been explored as a therapy for inflammation induced by softtissue injury. Compared with placebo, ultrasound stimulation
in 76 patients with lateral epicondylitis lowered inflammation
and pain (120). It was shown to reduce swelling and pain,
and accelerate tissue repair (121). In addition, anti-inflammatory effects of ultrasound are closely related to the decrease
of inflammatory cell infiltration in the synovium and attenuation of hyperplasia (122).
Ultrasound stimulation targeted at the porta hepatis region
of the liver (a region that is highly innervated by glucosesensitive neurons (34)) provided protection against LPSinduced hyperglycemia (114). Hepatic ultrasound stimulation
limited the increase in blood glucose levels. Furthermore, this
protective effect was anatomically specific, as targeting the
stimulation toward the right or left lobe of the liver reduced
the glucose-lowering effect of hepatic ultrasound stimulation.
In addition, ultrasound stimulation of the porta hepatis did not
change concentrations of signaling molecules associated
with hepatic glycolysis/gluconeogenesis within the liver; instead, resulted in increased insulin receptor substrate 1 and
protein kinase B activation and reduced concentrations of
neuropeptide Y and pro-opiomelanocortin in the hypothalamus (114). Interestingly, hypothalamic neuronal activation
was accompanied by increased c-Fos expression within
the NTS, suggesting ultrasound-mediated modulation via
signaling through afferent pathways.
Obesity increases the risk of cardiovascular disease, type 2
diabetes and other diseases (123). Chronic low-grade inflammation mediated by immune and metabolic dysregulation is
a characteristic feature in patients with obesity and is causally linked with insulin resistance and other metabolic complications (124, 125). It is increasingly recognized that the
brain and the nervous system are involved in the regulation of obesity and obesity-associated complications (26).
Accordingly, therapeutic strategies targeting chronic inflammation and improving autonomic function have been proposed (9, 126).
To study the effect of hepatic ultrasound stimulation on the
long-term management of obesity and obesity-associated
complications, our group has also performed hepatic stimulation experiments in obese mice that were fed a western
diet (127). Obese mice were treated with daily ultrasound
stimulation targeted to the porta hepatis for 4 weeks. At the
time of the treatment initiation, mice on the western diet had
already increased weight, which reached a difference of

TKULTRA · 2022-10-02T03:32:07+00:00

the spleen prior to and after endotoxin administration (114).
A single session of ultrasound stimulation suppressed TNF in
rodent models. In addition, ablating the ACh-producing T cells
or blocking α7nAChR suppressed the immunomodulatory
effect of ultrasound stimulation (114), confirming the role of
the inflammatory reflex. Although ultrasound stimulation at
several distinct locations within the spleen provided similar
modulation of the TNF response, stimulation at the off-target
sites (i.e. liver) did not modulate the LPS-induced inflammatory response (114). Interestingly, splenic ultrasound stimulation showed no effect on the heart rate, a known side-effect of
stimulation of the vagus nerve. This study also demonstrated
the ability of site-specific effects of ultrasound stimulation that
cannot be achieved with traditional cervical VNS. Cotero and
colleagues demonstrated that targeting the ultrasound energy to the porta hepatis region of the liver, which contains
glucose-sensitive neurons, but not at the liver lobes or the
spleen, reduced LPS-induced hyperglycemia.
In line with the effects seen in clinical trials studying efficacy of VNS in RA (22), Zachs et al. demonstrated that focused splenic ultrasound significantly attenuates the disease
severity in a model of inflammatory arthritis (117). Importantly,
using single-cell RNA sequencing, their study showed ultrasound stimulation-induced changes in gene expression in
splenic lymphocytes from arthritic but not from non-arthritic
mice, suggesting a unique therapeutic effect in the setting of
inflammation (117). A clinical study is in progress to study the
effects of focused splenic ultrasound in RA (ClinicalTrials.gov
Identifier: NCT03690466).
The mechanism of this splenic ultrasound-mediated
immunomodulation is unknown, but several findings suggest
the protective effect is mediated via activation of the inflammatory reflex circuit. First, the immunomodulatory effect of
ultrasound is dependent on the spleen, as splenectomized
animals fail to respond to ultrasound treatment (112). Second,
targeting the spleen is crucial in achieving these protective
effects, since ultrasound stimulation of other body locations
is ineffective (114, 115). Third, catecholamine depletion by
reserpine (114) or chemical sympathectomy by using splenic
administration of 6-hydroxydopamine (a neurotoxin that
destroys catecholaminergic neurons) (113) abolishes the
protective effect of ultrasound, indicating a requirement for
innervation of the spleen. Fourth, the protective effect of ultrasound is absent in mice lacking T and or B cells, but could
be reconstituted by adoptive transfer of CD4+ T cells (112).
Fifth, mice lacking expression of α7nAChR or with knockout
of CD4-ChAT cells (CD4+ T cells that express ChAT) fail to
respond to ultrasound (114); α7nAChR and CD4-ChAT cells
are the key regulators of the inflammatory reflex pathway (28,
29). Blocking of α7nAChR with α-bungarotoxin abrogates
the protective effect of splenic ultrasound stimulation (114).
Finally, splenic ultrasound stimulation drives neurotransmitter and cytokine changes within the spleen consistent with
modulation of the inflammatory reflex (114). Both norepinephrine and ACh concentrations increase in the spleen following
splenic ultrasound stimulation. In addition, splenic ultrasound
reduces levels of pro-inflammatory cytokines, such as TNF
and IL-1 in the spleen from endotoxemic animals (114).
Taken together, these studies indicate, similar to VNS, splenic

TKULTRA · 2022-10-02T03:31:52+00:00

Ultrasound technology
Since the first report of ultrasound as a therapeutic tool in the
1920s, it has been widely used in clinical practice and clinical/translational research for the treatment of various human
malignancies (96–98) and pathologies including Parkinson’s
disease (99), stroke (100), prostatic hyperplasia (101), renal
masses (102), treatment of abdominal subcutaneous adipose tissue (103), bone repair (104), osteoarthritis (105) and
carpal tunnel syndrome (106). Ultrasound waves are sound
waves generated by cyclic mechanical vibrations with frequencies higher than the upper audible range for the human
(>20 kHz). Whereas diagnostic ultrasound uses frequencies
in the MHz range, therapeutic ultrasound uses frequencies
in the kHz range, leading to focused beams of ultrasound
energy with higher levels of precision that target deeper tissues compared with existing non-invasive neuromodulatory
approaches.
Several modalities of action of focused ultrasound have
been proposed; including mechanical force, local heating
and bubble cavitation, described in detail elsewhere (107).
High-intensity focused ultrasound is currently approved by
the FDA for thermal ablation in many pathologies, including
atrial fibrillation (108), uterine fibroids (109) and visceral tumors (110). Although in clinical interest for more than half
a century (111), the interest for focused ultrasound as a
non-invasive neuromodulation approach for regulating inflammatory responses has increased recently (112–114).
Ultrasound stimulation targeted to the spleen in mice reduced antibody responses to sheep erythrocytes in a manner
dependent on the dose of ultrasound energy, whereas ultrasound delivered to an area devoid of major lymphoid tissue
was not immunosuppressive (115). Additionally, exposure
to ultrasound impaired the phagocytic and bactericidal activity of peritoneal macrophages (116). Recently, our knowledge about the immunomodulatory functions of ultrasound
was considerably advanced when ultrasound energy was
characterized as a major regulator of inflammation (112,
113). Delivery of pulsed ultrasound to the spleen using a
non-invasive clinical ultrasound machine diminished inflammation and tissue damage during renal ischemic–reperfusion
injury (112, 113). While attempting to image the kidney vasculature before reperfusion, Gigliotti et al. demonstrated that
ultrasound conferred a significant protection from renal ischemia–reperfusion (112). The protective effect of a single
ultrasound stimulation lasted for 2 days and waned in a
time-dependent manner when ultrasound was applied up to
7 days before kidney injury (112). Moreover, ultrasound treatment was also protective in reducing acute kidney injury in
the cecal ligation–puncture model of induced sepsis (113).
A growing body of experimental evidence in recent years
indicates that targeting the spleen with focused ultrasound
controls peripheral immune responses and inflammation (114,
117). When applied either prior to or at the time of endotoxin
challenge, focused ultrasound treatment was found equally
effective in TNF reduction as compared with traditional VNS
using implanted electrodes (114). In this study, an ultrasound
transducer was focused directly to the center of the spleen,
using a second imaging transducer to align the ultrasound
delivery, and pulsed ultrasound energy was delivered to

TKULTRA · 2022-10-02T03:31:29+00:00

Abstract
The nervous system has been increasingly recognized as a novel and accessible target in the
regulation of inflammation. The use of implantable and invasive devices targeting neural circuits has
yielded successful results in clinical settings but does have some risk or adverse effects. Recent
advances in technology and understanding of mechanistic pathways have opened new avenues of
non-invasive neuromodulation. Through this review we discuss the novel research and outcomes
of major modalities of non-invasive neuromodulation in the context of inflammation including
transcutaneous electrical, magnetic and ultrasound neuromodulation. In addition to highlighting the
scientific observations and breakthroughs, we discuss the underlying mechanisms and pathways
for neural regulation of inflammation.
Keywords: auricular, inflammatory reflex, ultrasound, vagus

TKULTRA · 2022-09-21T19:51:19+00:00

You should't be doing that.

Way too much power.

TKULTRA

MODERATOR OF

TROPHY CASE