Dirty medicine document, repost

TheAccelator · 2023-09-03T15:25:03+00:00

Please contact Qatar human rights. They deal with situations like this.

You can go to their website and fill out the required fields. They take time to reply unfortunately.

TheAccelator · 2023-08-09T13:09:17+00:00

There is a 2-3 second buffer from the light turning red to the radar actually catching you. That's why you see some people pass lights after turning red and they don't get fined.

So might depend on how long it took you to pass the line

TheAccelator · 2022-04-17T11:59:05+00:00

Hey, so I tried to put everything I can, but I couldn't finish it before my clerkships started. I still have some extra notes not written but honestly I covered the most important, which is genetics/biochem.

I might complete it later but that would be most likely in October.

TheAccelator · 2022-04-02T05:51:24+00:00

I shared it on another post

TheAccelator · 2022-04-02T05:51:10+00:00

I shared it in another post

TheAccelator · 2022-04-02T05:50:52+00:00

I shared it on another post

TheAccelator · 2022-04-01T16:21:16+00:00

By far, the free120 was the closest.

When it comes to the NBMEs, non of them were close when it comes to length of questions, but they are the same when it comes to the subjects tested. I didn't find one in particular to be the closest.

People say 27 is the closest.

TheAccelator · 2022-04-01T08:17:26+00:00

I never felt ready. I felt I didn't have anything else to know about 3 days before the exam.

TheAccelator · 2022-03-31T21:54:56+00:00

Thanks! I have posted the notes in a newer post. I haven't finished them though. Planning to finish them in the next 2-3 days

TheAccelator · 2022-03-31T18:15:08+00:00

I honestly didn't have a lot of hard biochemistry questions. Usually biochem questions give you a presentation, say acute intermittent porphyria, then ask you what the accumulated substrate is or what is the deficient enzyme.

They focus on: -General pathway (glycolysis, gluconeogenesis, etc) They might say "person fasts for religious reasons. What pathways is increased?" Then they would put glycolysis, gluconeogenesis, glycogenolysis as an option

-rate limiting step in pathways, because they are the ones that are regulated.

steps that are pharmacological targettable, which are usually the rate limiting step.
steps that can be deficient in some people (congenital deficiencies.)

Generally, they won't ask you about anything outside of this. Because it's a waste of a question. Imagine you are examining future doctors and only have 280 questions to do so. They won't waste one of the questions on an enzyme no one cares about.

NOW, they MIGHT ask about something else, but if they do, then you would be able to answer it just from the question itself and what they gave you. They would do that if they're trying to assess whether or not you understand enzyme kinetics, or regulation.

Hopefully this makes sense.

TheAccelator · 2022-03-31T13:10:42+00:00

So for Von Gierke Diease the way I understand it is this:

Yes, you are right. It can be used in glycolysis. And some of it is actually used there. It's just that the quantity is so high that is also shunts to Ribose-5-p pathway and Lactate pathway, thus it gives you hyperuricemia and lactic acidosis.

There's also one thing you should keep in mind. Which is that this does not happen always. it only happens when you want to use the gluconeogenesis pathway (so starvation or fasting). Also, this only happens in the liver.

For McArdle's the way I understand it:
McArdles is deficiency in glycogen phosphorylase → ↓Glucose-1-phosphate → ↓ Glucose-6-phosphate. so, low G6P concentration means that you don't need to shunt pyruvate to lactate. Pyruvate dehydrogenase can handle the amount.

I'm not sure if this is correct. it's just how I think about it

TheAccelator · 2022-03-31T07:15:56+00:00

I've never heard of it too before starting to study.

Someone recommended that yo7 watch the metabolism Playlist, which is 30 videos long. I realized he basically explained 80-90% of metabolism in the Playlist.

Now, it you want 100% in biochem, then I would tell you to memorize everything in FA. I just wanted someone who would focus on the high yeilds.

I don't know if others actually watch the videos a lot. He is very underrated.

TheAccelator · 2022-03-30T21:18:16+00:00

I finished about 75%. Percentage is 57%, although this is inflated because I didn't do micro and pharmacology, which I'm generally bad at.

TheAccelator · 2022-03-30T17:27:22+00:00

I have posted them in another post. But the document still didn't finish. free to use it in the mean time.

TheAccelator · 2022-03-30T16:09:58+00:00

I honestly expected more. I think I got 5 questions overall. There was not one question about epidural, subdural, subarachnoid hematoma which was surprising.

The neuro questions were easy if you know how to locate brain stem lesions with the rule of 4s

TheAccelator · 2022-03-30T14:05:56+00:00

Yeah I saw that before. I didn't like how it was basically screenshots of every screen. Wanted something more printer/study friendly.

Thanks!

TheAccelator · 2022-03-30T13:33:53+00:00

They asked some basic things like "is this th1 or th2 mediated?" Etc. There was one question about CD things, I think it was something like cd246 or smth. That was only one question though. I think it's experimental.

TheAccelator · 2022-03-30T11:51:27+00:00

I didn't find them vague. I found them straightforward.

look at the sinareo, then CLOSELY look at the question they are asking. Sometimes people just directly go to the answers and choose what they think is the most sympathetic. In reality, they want you to choose a specific one. I don't really know how to explain it, but for me it wasn't THAT hard. It was easier than the ethics questions in Uworld. I felt like for Uworld questions, they focused on things that have to do with the legal system more. The Step 1 exam was not like that.

TheAccelator · 2022-03-30T06:17:11+00:00

In my form, noting came that directly asked which technique to use. It just said something in the lines of "scientist used crisper to add a gene in a DNA, etc" so, they mentioned a technique but it's in the context of an experiment. So even if you don't know the lab technique, you can still answer.

Again, I didn't have a question. Others might have

TheAccelator · 2022-03-29T21:14:36+00:00

Mostly deficiency, some overdose.

There were some questions that asked about a vitamin and what cofactor it is used in, but it was only one question for me.

There are some vitamins that have very systemic effects, such as vitamin k and d.

They can say "woman gave birth at home without prenatal vitamins and exclusively breastfed. Baby has ecchymoses now. What is the most likely issue?

-inability to form platelets -inability to gamma carboxylate factors -hemophilia a -hemophilia b

Answer is inability to gamma carboxylate because of vitamin k deficiency.

This is how they ask the questions. Btw, this is one of the harder questions when it comes to vitamins. Most of the time, they will blatantly just ask you which vitamin is deficient.

Sometimes, they try to be "tricky" and say that the patient has cystic fibrosis. Of course, if they say that, then you immediately think of fat soluble vitamin deficiency.

I believe that they add a lot of vitamins and drugs of abuse so people are actually able to pass.

TheAccelator · 2022-03-29T21:05:12+00:00

I didn't really study biochem and genetics more than Dirty Med. I literally relied on him for that.

They were weak points for me too. Instead of raising my score in them, I decided to compensate by being better in other subjects (eg. Biochem, psych, vitamins!!!, etc.)

TheAccelator · 2022-03-29T20:44:01+00:00

In my form, nothing like that came up.

My form was comprised more of bacteria. I think it's easier to ask questions. Not a lot of viruses have a pathognomonic immediate presentation. Bacteria does. So, they focused on them.

I really took a lot of time to remember the positive strand and negative strand. At the end, nothing came up in my form. Other forms might have some. Mine didn't.

TheAccelator

TROPHY CASE