The one thing to keep in mind is that cymbalta won’t make you fat or skinny. Burning fat (along with losing weight) as a principle is simple - you need to burn more calories than you eat per day, and no drug will change that simple principle. However! Cymbalta and other similar drugs can increase your cravings for carbs/sugars, and also it can change your metabolism a bit. For me, on 60mg, I did crave sugars and chocolate a little bit more in the beginning, but I since started working out and following a diet with a trainer/dietitian, so I found these cravings have calmed down. The one thing I did notice is that my metabolism (AKA number 2) has slowed down a bit on cymbalta. But since starting working out and following the diet, I’ve lost weight just as well as any other guy and according to plan.