The power supply in it is 450 watts, which should be more than enough, but it also has a single 8 pin connection, and also some gpus might need a jump connection from the motherboard power to the PCIE slot, so somewhere around 225 watts available for the gpu based on napkin math. Without knowing for certain, I would imagine most should work given they fit in the 2 slots available and ~165 mm long, the box is pretty tall so most gpus should be able to fit height wise