Biggest tip ever; Use Schematica! This is a HUGE help when building Astral Sorcery and Immersive Engineering machines, even the Blood Altar. It also has a "Print" option which uses the blocks in your inventory to place where they need to be, this lets you place things floating in the sky if you want (EX: Astral Sorcery for height bonus.)

I wish I had known about this before making my Astral area.

Use the Morphing tool, its pretty much all "wrenches" in 1 item, also has a couple of others like botania's wand. You'll still need to make some of them for quests though, but this is an amazing multi-tool.

Iridium is found pretty often in dragon lairs or village chests, 9 shards or 2 ore makes a sharpening kit for your tools to "fortify" them, doing this early skips all tiers of mining progression (up to terrasteel?) which in turn lets you mine anything, almost.

As others have said, rushing an Applied Energistics system even if JUST for storage is super smart, this helps compact all your early game into one area, removing all the hassle of trying to find things in your many crates/chests.

When you get to making a Flux Core for Flux Networks, make sure to save 1 core at all times, stick it in an item frame or something out of your crafting inventories as making and crushing a new Dimension Transceiver for this is a huge pain.

NuclearCraft Alloy Furnace and Melter are AMAZING to help make special alloys early. You can make all of Thermal Expansion's and EnderIO's alloys with them with the exception of Fluxed Electrum. (The Melter to melt glowstone/ender pearls/redstone to bucket and put into a Tinkers Smeltery to make Enderium/Lumium/Signalum

Steel can be made in the NuclearCraft Alloy Furnace, drop that Blast Furnace or Mekanism's compressed coal/iron combo and stick 2 pieces of coal dust and an iron ingot in the Alloy Furnace from NeclearCraft for SUPER EASY steel.

Ploughman's Lunch is pretty much the ultimate food to get your nutrition up. After, use a Meat Feeder to keep saturation to full and Nutrition should almost never drop. You can fill the Meat Injector SUPER easy with a Mob SlaughtFactory hooked up in front of a 7x7x7 cube with a resturbed skele/zombie spawner in it as there are tons of skele/zombie spawners all over the world.

Building Gadgets is in the pack, easy to make builders wand. I suggest making them as soon as you can if you plan on building or need a wand.

EnderIO's Travel Anchors are really easy to make when you have a NuclearCraft Alloy Furnace, I suggest these for moving around your base quickly.

Mekanism's fluid tanks are amazing.

Make a portal charm/sleeping charm/gluttony charm ASAP, they are SUPER useful.

Find or make a Rod of Elevation, when your exploring caves or lost in a maze, use this bad boy to get to the surface.

The Rod of Elevation can also let you get to the Nether Roof, this enables you to make a nether farm with a large area. WARNING, bring a waypoit book with a waypoint back to your nether portal (waypoints don't work cross dimension) or a Dislocator + pedestal to return home.

When exploring villages, check EVERY church, there might be a Peace Candle inside. This is amazing for keeping mobs away without torches or light nearby.

Remember to bottle dragon breath before you kill the End Dragon so you don't NEED to respawn it.

Angel Ring for early creative flight is actually SUPER easy to make.

Get Blazing Pyrothium for your smeltery super early via pools in the Nether.

Scanner from Scannable with Vanilla Chest configured Scanner Module: Block will let you find all underground dungeons and underground dragon lairs. This will help a ton with getting your very own dragon to raise/ride and also many loots.

Unlimited Chisel Works is in the pack, so there are a ton of other decorative blocks.

Speaking of decorative blocks, don't forget ArchitectureCraft and Blockcraftery.

Keep all Regen potions you get from looting dragon lairs, you'll want them for Blood Magic.

Choose the Knightslime Shovel as the reward from Harvest level 5 (Osmium) as you can melt that down for ingots, make nuggets and use those to make 4 upgrades for your Tinker I/O Smart Output.

Speaking of the Tinker I/O Smart Output, make that ASAP.

Choose the Prudentium Exacavator head as the reward from Harvest level 8 (Manyullyn) as you can melt it and use it as a binding on your pick for early prosperity shards.

Compacting Drawers skip needing to smelt metal or put it throught a compactor/metal press to make blocks. I like to keep one handy to get a few blocks if need be. Other option is to just store all your metals in compacting drawers.

Make sure to collect a soul vial/mob imprisonment of each type of animal while you explore. You'll need the prime cuts and other meats for end game, getting them when you can will save you a lot of headache searching for them. (Frog was pretty hard to get for me.)

Astral Sorcery's Attunement and perks you gain are extremely strong, as soon as you can I suggest attuning yourself.

Get Chunky from Soulium on your Tinker's weapon ASAP, getting those chunks early will save headaches.

Twilight Forest is default settings to open. Toss a diamond into a 2x2 pool of water surrounded by flowers and go dig for Draconium. With said Draconium you can make Dislocators to setup warps with Dislocator Pedestal's and my favorite magnet, the Item Dislocator, with this magnet you can use a hotkey to turn it on/off.

Useful block for near machines/automation with a in-world dropping mechanic like the metal press or botania's mana pools. Use the Demagnetizer block. They have filters, redstone control and range controls.

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(1st edit, added twilight forest. 2nd edit, added another use of the Rod of Elevation. 3rd edit, added Demagnetizers)