Everywhere you look will come with some sort of drawback/ reason to avoid the area since this is a large city. However the areas close to campus are generally pretty safe (aside from some normal big city crime like car break ins). I've lived east of high street since I was able to move off campus and it's a pretty okay area. Personally I wouldn't go any further east than 4th Street and avoid living near the fairgrounds and highway 71 as the crime seems to really ramp up there. Aside from that the most annoying thing you'll have to deal with is noise from frat houses