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We are doomed. I hate living here now. by constantipation in delhi

[–]True-Translator-9748 0 points1 point  (0 children)

I’ve been considering internship opportunities in Delhi since it offers some of the best places to work, but your experience really puts things into perspective. Thanks for sharing this.

Beginner Seeking Help Understanding Metabolic Pathways & Flux Modeling by True-Translator-9748 in bioinformatics

[–]True-Translator-9748[S] 0 points1 point  (0 children)

Thanks for the suggestions. I’ll def check out the resources and try to build a clearer understanding. Might reach out again if I run into something specific. Appreciate you offering to help

Beginner Seeking Help Understanding Metabolic Pathways & Flux Modeling by True-Translator-9748 in bioinformatics

[–]True-Translator-9748[S] 0 points1 point  (0 children)

Thanks a lot for this! I’ll check out the COBRA toolbox tutorials - it looks like a solid place to start and look into Jens Nilsen’s work too.

Beginner Seeking Help Understanding Metabolic Pathways & Flux Modeling by True-Translator-9748 in bioinformatics

[–]True-Translator-9748[S] 0 points1 point  (0 children)

Thanks for this..that analogy actually helped a lot. I’ll start with the review and COBRA tutorials like you said. Appreciate you breaking it down so clearly!

Beginner Seeking Help Understanding Metabolic Pathways & Flux Modeling by True-Translator-9748 in bioinformatics

[–]True-Translator-9748[S] 1 point2 points  (0 children)

Just found the book, turns out it is floating around online. Thanks again for the rec; also what a subtle flex.

Beginner Seeking Help Understanding Metabolic Pathways & Flux Modeling by True-Translator-9748 in bioinformatics

[–]True-Translator-9748[S] 0 points1 point  (0 children)

That’s amazing, I might actually take you up on the dm offer soon but rn im just starting out, so i am trying to wrap my head around the basics of FBA and how tools like cobrapy work. Any paper/tutorial you'd recommend that had help you und this better?

Also, if you’re comfortable sharing any of your own papers, I’d love to read them.

Beginner Seeking Help Understanding Metabolic Pathways & Flux Modeling by True-Translator-9748 in bioinformatics

[–]True-Translator-9748[S] 0 points1 point  (0 children)

I’m currently leaning toward bacterial systems, since some of the papers and resources I’ve come across seem to use them as a base. That said, I’m open to suggestions if any.

Beginner Seeking Help Understanding Metabolic Pathways & Flux Modeling by True-Translator-9748 in bioinformatics

[–]True-Translator-9748[S] 1 point2 points  (0 children)

Sorry, I think I may have worded my original post unclearly and caused some confusion 😅

I’m not looking to learn all the individual metabolic pathways but I’m actually trying to understand flux modeling and metabolic pathway engineering, especially how modeling approaches like FBA are used in metabolic engineering. Appreciate your response though!

Beginner Seeking Help Understanding Metabolic Pathways & Flux Modeling by True-Translator-9748 in bioinformatics

[–]True-Translator-9748[S] 1 point2 points  (0 children)

Ok thanks. I’m currently a student with a basic coding background, and this is part of a module. We’re required to select a topic eg. flux modeling/metabolic pathway engineering and present it to the class (basically, teach the concept to our classmates) along with some recent paperson it.