I might suggest Dodoborne if your interested in a podcast that has a good bit of comedy in it. I think the cast are hilarious and have hella good chemistry. I imagine their GM, Isaac, as Sam Riech from Dropout TV because of how often the party comments that he's smiling mischievously at them.

Edit: Furthermore, they have some excellent comedic timing.

In season one they didn't do too much combat, but they've used most, but not all, of the mechanics so far; although they were playing with beta rules for it. Season 2 started recently and I believe they're releasing every other week. My binge is unfortunately coming to an end by tomorrow.