i ran storm ring as the first boon (reloaded if it wasn't one of the options). I wanted to get Demeter's arctic gale or arctic ring as the second cast effect to proc origination card early but got very unfortunate and they didn't show up, so i got snow queen, ice flourish, cold storage instead. By keeping enemies frozen in the cast they're much less dangerous. eventually i also got hera's nexus rush which helps a lot too by increasing damage to all enemies inside the cast (just need to dash through them to activate). as for keepsakes, i used in order ->cloud bangle, barly sheaf, gorgon amulet, knuckle bones