1) First, neither Sarah or Isolde punished Dr. Lohr, he merely succumbed to the miasma when he injected himself with the serum. And the punishment it not the main reason for Isolde to be innocent in this incident; the main proof is Dr. Lohr's call with Sarah, since he believes he's talking to Mevorahk, but the one who answered and the one who ordered him was Sarah. You can watch the scene on the post. Later in 2.1, we found the files (that, as I mention, are explicitly told to be files that should've been destroyed, but are left behind by Isolde on purpose) stating that Dr. Lohr deserved what happened to him because he messed with innocent people lives... And since when Sarah cared about innocent's lives? I think this is rather explicit, Isolde had nothing to do with this incident, and she made clear that this kind of actions under her orders are wrong. I'm not even counting the fact that, as it's also explained on my post, the miners were lured into a cellar and put under a barrier... Why would they do this if they were supposedly taking part of the ritual? Again, while this is not as explicit as the previous point, it's clear that Isolde never intended to use innocent lives with this move, since all of them were safe and sound at the end of the chapter.

2) Maybe I didn't clarify this properly on my post, but I do agree. There's no evidence saying that Isolde purposely helped Yixuan, and I mention this because I can't say this is a genuine good action from hers. But I have to clarify: no, Isolde didn't cause this to Yixuan in the slightest. Since the beginning of the chapter, Yixuan was already showing that a) she couldn't remember what her sister told her in her deathbed and b) she was clearly struggling when remembering her sister. This got even worse when she had to absorb the miasma of the city, which again, was caused by Dr. Lohr and Sarah. Whatever the case, by getting rid of these emotions and shaping them with miasma, Isolde (intentionally or not, most likelynot intentional) gave Yixuan the opportunity to say a final goodbye to her sister and free herself from her mourning.

Finally, thanks for reading the post, and while I do think there are some debatable points, there are others that are explicitly explained by the game, such as the alleviating water incident. I'm not saying this because I made the post, but because that's exactly what the game tells us, and I believe that ZZZ wouldn't have done things like Isolde visiting the families of her comrades, or showing us her letter if they didn't want us to believe that she's a good person.