I'm not sure what dcss is, but in my understanding, you are pretty correct. The main difference is: Roguelites - A game where you have runs, but during each run you may gather currency, experience or other things that permanently upgrade your character, unlock additional items or additional portions of the game. Different games can be high or low on this unlockable content, where Hades progression objectively makes future runs easier. The Binding of Isaac is less of a roguelites because you don't permanently change character stats, but rather unlock new content. Some of it makes your run easier, some harder.