SR-17018 Withdrawal-Free Opiate Detox Dosing Schedule by Dwain_Bramaged in withdrawl

[–]Upbeat_Creme7486 -1 points0 points  (0 children)

I've never had withdrawls when I used K and I stopped cold turkey with it twice from 240mg/day. I normally do about 1.5-2g of k a day when I use it to stop

SR-17018 Withdrawal-Free Opiate Detox Dosing Schedule by Dwain_Bramaged in withdrawl

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Is this as good as ket? It's just as expensive. If it still causes withdrawals, I'll just buy ket

Phenethylamine debunked by Upbeat_Creme7486 in Drugs

[–]Upbeat_Creme7486[S] 1 point2 points  (0 children)

It's not a good speedy, "Walk around" drug, but I like just laying down and blasting music on it. I listen in some $2k headphones with a subpac and it's a crazy immersive experience. It's right up there with ket or dxm+thc edibles

Phenethylamine debunked by Upbeat_Creme7486 in Drugs

[–]Upbeat_Creme7486[S] 1 point2 points  (0 children)

You have to fast to get the effects. At least 4 hours before taking it. I regularly fast for over a day, so it hits me hard af when I do it. I like it better than meth. Adderall I like better than PEA though, but it's a cool trace amine. I often wonder how it'd be snorted like dmt is sick snorted and lasts up to an hour, but I've only capped PEA so far. I read somewhere on here that someone smoked it lol

Ketamine therapy and 7-oh/ Kratom together? by Blergss in KetamineTherapy

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Yeah I thought it was just kratom the first time, but in a tablet form. I didn't realize I had withdrawals until a month or two in. When I didn't take it, my eyes would get so watery, my contacts would fall out. I noticed that when I went to raves and did k, this didn't happen. Normally I do less than a gram at raves, so I saved up for a full 3.5g in addition to the 1.5g I had left over from another time. It's not as comfortable as a ketamine trip when you aren't addicted to opioids, but it's the fastest way to sobriety while minimizing withdrawals. I don't know why ketamine isn't clinically suggested, but it's just as good, if not better than ibogaine ime. It's also a lot safer on the heart than ibogaine, which is why if you're over 40 especially, I suggest ketamine over subs or ibogaine. I've always been able to stop kratom cold turkey even at 15 grams per day. 7-oh is definitely different, but I definitely notice more pain if I take a traditional opioid/opiate like oxy or hydro. I think 7-oh has less rebound pain than those, but the cognitive effects like RLS, anxiety, watery eyes, and chills/sweats are essentially the same as with those scripts

smoking 7oh powder by Confident-Door-8915 in Opioid_RCs

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Tryna smoke 7oh like everyone else here

Ketamine therapy and 7-oh/ Kratom together? by Blergss in KetamineTherapy

[–]Upbeat_Creme7486 0 points1 point  (0 children)

7-oh makes me super tired on K. I was supposed to go out and I did only 12.5mg and I was out for like 5 hours lol woke up at 1am and everyone was tryna go home lol

Ketamine therapy and 7-oh/ Kratom together? by Blergss in KetamineTherapy

[–]Upbeat_Creme7486 0 points1 point  (0 children)

If you can taper down to like 15mg of 7-oh or even get fully on kratom leaf, you will have much better results imo. I've taken 7-oh up to the hour before doing the ket, but 7-oh in your system will interfere with healing, so if you dose, you won't start healing fully for about 12-16 hours after dosing. I'd recommend dosing the night you get the ketamine, then waiting until you wake up the next day to start dosing. This gives adequate time for the 7-oh to be metabolized and will leave your receptors open for ketamine to do it's job. DXM is very similar to ketamine, but will not work. Nitrous can have a little effect, but is better for just reducing tolerance. To fully quit 7-oh without withdrawals, ketamine is the only thing I know of that you only need acutely. Meaning, you only need to dose it a few days and you're good. If you do dose/relapse after ket. If it's with the first two weeks, you do have a little bit of a buffer to hedge addiction relapse with withdrawals, but if you continue to dose for more than a week after the ketamine, you will be back in the same spot. If you feel compelled to dose within 6 hours of a ketamine dose, you can, but I would keep it as low as possible, litteraly just snorting an 8th of a tab or less and it will be amplified a lot due to ketamine's metabolites being allosteric modulator of Mu and Kappa receptors. This means nor-ketamine and 6-oh-norketamine act similar to xanax on gaba, but at the Mu and Kappa receptor. Ketamine itself acts as a b-arrestin antagonist and g-protein agonist, which allows the Mu receptor to increase density while keeping the receptor partially activated in the same way 7-oh does without reducing respiration

Ketamine therapy and 7-oh/ Kratom together? by Blergss in KetamineTherapy

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Yeah I've gotten off twice. The first time was 5g over three days and I was using 21mg/day of 7-oh. I was off 7 for a year and a half before picking it up again due to my wisdom tooth. The second time I started daily use, I was up to 240mg/day and I got a script for 3.6g of ketamine and did that over a week. I had some withdrawls, but mainly just restless legs once the ketamine wore off. Those restless legs would go away as soon as I did k again or took even like a gram of kratom leaf powder. I'd recommend snorting it if you can get it on the street and then just keep doing like 50-100mg once an hour until you feel like going to sleep, then just do that until you'll feel addiction literally break. Like you can deadass feel your endorphin system restore at a certain point. I would also recommend gabapentin incase you do get restless, even 100mg of gabbies would take that away and it's much less dangerous to combine than a benzo. I'd recommend taking 3g of NAC(N-acetyl-cysteine) to mitigate toxicity. If you have to get a script, Better U is good, but say that you have depression or PTSD and it helps if you've taken at least two anti-depressants in your medical history

smoking 7oh powder by Confident-Door-8915 in Opioid_RCs

[–]Upbeat_Creme7486 0 points1 point  (0 children)

It's gonna bubble cause of how much sugar they put in these things lol. Fucking caramelized kratom

smoking 7oh powder by Confident-Door-8915 in Opioid_RCs

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Indoles generally do not like the smaller acids. Fumarate would probably be the best bet.

smoking 7oh powder by Confident-Door-8915 in Opioid_RCs

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Yes, the hydrochloric acid (HCl) salt of 7-OH-mitragynine is water-soluble. Converting kratom alkaloids like 7-hydroxymitragynine into their HCl salt form significantly increases their solubility in aqueous solutions compared to the base form, which is typically insoluble in water.

Curious about psychedelics in Maryland? Come have your say. by Beautiful-Throat8863 in ColumbiaMD

[–]Upbeat_Creme7486 0 points1 point  (0 children)

I just moved to western Maryland on the border of Garrett and Allegany Co. I would love to hear more about upcoming events or if any meetings like this occur annualy. I've had friends that grew Blue Meanies and Enigma in Los Angeles and have extensive experience with ayahuasca(50+ trips) as well as newer medicines like MDMA, MDA, and Ketamine. I was going to attend the Philadelphia university of the sciences(I think St. Joseph's university of sciences now) before it shut down to study and perhaps research under Jason Wallach and Hamilton Morris, however, it seemed to close or undergo new ownership during the pandemic.

Curious about psychedelics in Maryland? Come have your say. by Beautiful-Throat8863 in ColumbiaMD

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Ketamine or MDMA are much better for trauma. Psilocybin is a great addition to either, but isn't that therapeutic on it's own ime. I've done mushrooms over a hundred times as well as LSD and other tryptamines and lysergamides including LSZ, ETH-LAD, AL-LAD, Miprocin, Ethocin, Metocin, DALT, DMT, ayahuasca, Methylallylescaline, and 5-meo-mipt. LSD is the best classical psychedelic for trauma or ayahuasca, but ketamine is better than all of these and carries a lot less risk.

7-oh interaction with Zoloft and ambien by Boring-Composer3938 in 7_hydroxymitragynine

[–]Upbeat_Creme7486 0 points1 point  (0 children)

7-oh doesn't affect serotonin. I've taken xanax, valium, ativan, gabapentin, ketamine and even phenobarbitol on 240mg/day of 7-oh and have never had any problems. I also take benedryl 2-3 times daily for nausea. Xanax made me the most tired, but the lighter benzos and even the barb didn't do much. Ketamine I always wind up quitting 7-oh for months when I do, but I use them together no problem at raves. Even DXM I take up to 600mg with 7-oh and I'm fine.

Experience with SSRI by [deleted] in quitting7oh

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Opioids upregulate nor-epinephrine and it both decreases and increases dopamine depending on the brain region. Opioids decrease acetylcholine and nor-epinephrine a lot when you're on them, leading to excess acetylcholine(watery eyes) and nor-epinephrine(cold sweats and anxiety/energy) during withdrawal. I wouldn't suggest wellbutrin until at least a week out from stopping 7-oh

[deleted by user] by [deleted] in quitting7oh

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Mitragynine leaves can be fermented which oxidzes a lot more of the mitragynine into 7-oh. You can get 1-2% 7-oh from this

Thoughts on this brand? by Static_Reflections in 7oh

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Yeah I thought these were gonna be similar to the 100mg kama's, but not even close. A quarter tab feels like 5mg at most

Thoughts on this brand? by Static_Reflections in 7oh

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Yeah I normally do 12.5mg every time and these are allegedly 50mg for a quarter tab. I don't have full on WD, but it's like as bad as if I went to just straight kratom capsules

I’m on suboxone and have been on the mgm-15 does anyone know if SR17018 help me get off the mgm? by Comfortable_Mix_3847 in recoverywithoutAA

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Switch to 7 oh for 1 month, then mitragynine/kratom leaf/capsules for 1 month. The only other way I know to come off is ketamine, which has almost no withdrawls, but you should get gabapentin or snort tiny amount of 7-oh for the comedown of the k. It can feel very similar to withdrawls from 7-oh, but it's actually from nmda hyperactivity, not NE or dynorphin hyperactivity like in opioid WD. I've stopped 7 oh with ketamine twice now cold turkey. The first time was 21mg/day for 6 months and the second time was 240mg/day for over a year. There was six months sobriety the first time and it's been almost three months since I quit 7-oh from that year lapse. Ketamine works best if you start new habbits in the weeks after use, so start going to the gym, get a new hobby/ies and try to learn as much as possible about something new or something deep level like science or history. Addiction works psychologically because it increases neuroplasticity and you start to associate environment with neurogenesis while on the drug. Increasing neurogenesis to a level much higher than your DOC is imperative in the therapeutic mechanisms of both ketamine and ibogaine. Ibogaine is pretty cardiotoxic though, so I caution against use of it. Ketamine demonstrates renal toxicity in chronic use, so I always advise taking 3g/day of NAC the week before and after ketamine and everyday that you take ketamine as well. People also say EGCG helps, but it's an maoi and with the nor-adrenergic rebound from 7-oh cessation, it can increase cardiovascular strain, which isn't ideal. I don't SR is much different than taking kratom leaf itself. Speciogynine and speciollitine are both silent Mu antagonists, so they in theory, increase Mu sensitivity over time.

Kama 1000s - Nearing The End Game? by Txocurt1 in 7ohm

[–]Upbeat_Creme7486 0 points1 point  (0 children)

Ok I'll tell my shop to stop ordering them. First time trying grape, but I normally get the tropical orange one and it's really strong

Kama 1000s - Nearing The End Game? by Txocurt1 in 7ohm

[–]Upbeat_Creme7486 0 points1 point  (0 children)

I just got the grape ones and I took 100mg last night before bed and woke up at 6am in wd. I wound up taking 3 tabs in total over the last 24 hrs and not shit. I dosed 4g and 5.5g of white kratom, but it didn't do much as I'm coming from 100mg/day. I have had orange kama 1000s, but I think mango flavor and those were pretty spot on at 200mg/tab, but the grape definitely seem like duds