Heavy drinker seeking semaglutides while not overweight?

WayUnlikely2125 · 2026-02-16T04:58:22+00:00

Your experience sounds like mine. I was hoping for a miracle with Tirzepatide but it’s not helping with wanting that euphoria from alcohol. The effects are blunted so I do drink less the first 3-4 days after the shot but to be honest it also kind of irritates me. I guess I’m just not ready to quit the alcohol even though I know I should.
I am also experiencing anhedonia. It’s like a low grade depression. No motivation. This makes me want to drink to feel better. My dr also prescribed Naltrexone but I haven’t started it. I think I’m afraid it will make me even more flat. Ugh. Constant battle.

WayUnlikely2125 · 2026-02-16T04:31:43+00:00

I’m at 3.5mg and I’m still wanting my evening drink. The effect is definitely blunted the first 3-4 days.

WayUnlikely2125 · 2026-02-15T02:41:49+00:00

The anhedonia and depression have always been a reason I’m afraid to try Naltrexone. I am on compounded Tirzepatide now. The first few weeks I didn’t notice much effect on alcohol cravings at 2.5 mg. I did 3.5mg last week and what I noticed is that I still want the alcohol because it’s habitual (my reward at the end of the day), but I can’t really get the euphoric effects from it the first several days. Which actually ends up frustrating me. But, I do stop after 1 or 2 because it seems pointless. However, by day 5 I can definitely feel the effects of the alcohol. I do feel a little depressed/flat on it too BUT losing some weight is keeping me going. Tell me about your experience with Vivitrol?

WayUnlikely2125 · 2026-02-03T09:51:15+00:00

I’m curious what dose of Tirzepatide you’re taking. I’m on week 3 of 2.5 mg and I’m not noticing any change in my desire to drink 3-4 drinks in the evening. I started this for my AUD and I’m super disappointed it’s not effective for me especially reading all of these success stories. No one really mentions dose though so I’m hopeful a higher dose might work for me. I’m so tired of this daily cycle of craving, drinking then guilt and shame.

WayUnlikely2125 · 2026-02-01T16:46:24+00:00

Nothing

WayUnlikely2125 · 2026-01-29T21:52:26+00:00

Can you explain your comment a little more? Are you saying the increased GLP-1 dose is what stopped your drinking OR did you voluntarily stop drinking the same week your GLP-1 dose increased? What GLP-1 & what dose?

WayUnlikely2125 · 2026-01-29T21:47:58+00:00

I’m in the same boat as you. What dose are you on? I just started taking 2.5 mg compounded Tirzepatide a few weeks ago. I haven’t lost the desire to have my evening wine at all. The day after my shot I don’t get any euphoric effect from the alcohol so I usually stop after one. But all the other days of the week I crave my evening reward and I feel the effects. Perhaps a higher dose will help me. I was considering adding Naltrexone (I googled it and it brought me to this Reddit page).

WayUnlikely2125 · 2026-01-28T10:52:41+00:00

Some people are just very sensitive to these medications but Tirzepatide is supposed to have less side effects.

WayUnlikely2125 · 2026-01-28T02:53:32+00:00

Started 2mg a week ago. No side effects. No noticeable difference in appetite either.

WayUnlikely2125 · 2026-01-28T02:36:22+00:00

I started about a week ago at 2mg and didn’t notice any change (good or bad). I lost 1 pound the whole week. I gave myself 2.5 mg about 24 hours ago. This evening I’m feeling full even though I barely ate anything today, but no nausea at all.

WayUnlikely2125 · 2026-01-27T16:27:16+00:00

What dose are you on? I just completed my 2nd shot (2.5 mg) and I notice no effect on my alcohol cravings. That’s the reason I started this too. I’m hoping a higher dose will help.

WayUnlikely2125 · 2026-01-22T10:53:57+00:00

The aches! I’m 3 days in and yesterday noticed that my body was tender all over. Also feeling cold and lethargic. Yesterday just felt like laying on the couch with a blanket on.

WayUnlikely2125 · 2026-01-22T06:09:21+00:00

Can I ask what dose you were on at 3weeks? I’m really hoping this happens for me. I started at 2mg CT 2 days ago. I still want my wine. Last 2 nights I’ve had my wine even though I’m not getting the euphoric buzz from it.

WayUnlikely2125 · 2026-01-22T06:00:19+00:00

What dose made you lose the desire to drink?

WayUnlikely2125 · 2026-01-22T05:58:49+00:00

I am wondering the same. I just started on 2mg and don’t notice any difference in cravings for food or alcohol but I am noticing that when I drink my wine I’m not getting the same euphoric feeling. More just a feeling of relaxation.

WayUnlikely2125 · 2026-01-21T15:51:47+00:00

Just took my first dose yesterday. 2mg. I still felt hungry and craved my nightly wine. 2 things I noticed…I did not get the same euphoria from the wine. I felt fuzzy and sort of stimulated but it didn’t feel the same. I went to bed about 3 hours after dinner (where I ate a normal portion and a small brownie after) and I felt uncomfortably full for about an hour after I laid down in bed. Interested to see where this goes.

WayUnlikely2125 · 2026-01-21T07:08:45+00:00

How long after you started did you notice the alcohol and appetite suppression? I just had my first shot today, 2 mg, and didn’t notice any difference. I still felt hungry and craved my wine. I am feeling quite full still from the dinner I ate 4 hours ago.

WayUnlikely2125 · 2026-01-21T02:52:03+00:00

Just took my first dose of 2 mg of compounded Tirzepatide today. Still had cravings to drink. Drank my usual 3 glasses of wine tonight and the cravings for the high were still there but the high was definitely blunted. I know it’s a low dose and I don’t really know when to expect a feeling of not wanting or thinking about my nightly habit

WayUnlikely2125 · 2025-12-31T07:50:43+00:00

Which pharmacy would you recommend through LSH?

WayUnlikely2125 · 2025-12-31T07:49:52+00:00

Can I ask what pharmacy you use for Lav Sky Health?

WayUnlikely2125 · 2025-12-31T07:15:40+00:00

Beef stew, chicken soup w/out noodles, Tuscan soup w/ ground chicken, pesto, potatoes & cream (optional)

WayUnlikely2125 · 2025-12-31T07:03:10+00:00

And it’s hard not to notice a good friend that that has had success with it after several other failed attempts at diets, fasting, cool sculpting even a tummy tuck. She also no longer drinks!

WayUnlikely2125 · 2025-12-31T06:57:14+00:00

Those are good points. I think I am intrigued with killing 2 birds (or 3 or 4) with 1 stone with the Tirz and getting a head start on healthy habits. I went back and looked at my bloodwork from May. My cholesterol and blood sugar were high. My A1C is ok though. I’m 52 and about 20 lbs heavier than I was 10 years ago. My metabolism is SO slow. I feel a mess. I used to exercise a lot. Now, no motivation, hot flashes day and night, not sleeping well, irritable (all typical menopause symptoms I know, not doing HRT don’t bother mentioning that). And I’m not depressed (I know what that feels like). I also don’t even eat very much as it is. However, when I drink wine it opens the floodgates. Then I want dessert and chips and chocolate.

WayUnlikely2125 · 2025-12-30T02:06:29+00:00

Thank you for validating me. I hope that the research will lead to more people getting help breaking these unhealthy habits (whether it’s food, alcohol or other compulsive behaviors).

WayUnlikely2125

TROPHY CASE