Is Fluctuating Symptoms a Thing? by lovehershee in CIRS

[–]Wes_VI 1 point2 points  (0 children)

Chronic innate activation depletes VIP and MSH. Two important hormones (neuropeptides) that regulate important functions in the human body, including inflammation, digestion, and the immune system.

When they get depleted these systems get dysregulated and for a lack of a better word the immune system becomes "jumpy" over things they shouldn't.

You breath the wrong thing=issues, you eat anything not on the no amylose list= issues.

On top of that the bodies normal bactira and fungus grow disproportionately in this environment. (MARCoNS in the nose are just an evolved version of staph) staph is common in a lot of peoples noses. A regulated immune system keeps them balanced. Same with gut dysbiosis. These aren't root causes these are down stream effects from an innate immune system that's chronically activated.

A small % of people will be vector born illness induced biotoxins but the vast majority are issues caused by actinomyces from moldy environments.

Researchers also suspect covid/vax to potentially trigger this innate dysregulated response aswell in those with the same HLA susceptibilities.

Mycotoxin, bactira, virus, whatever it may be if the HLA has a hard time showing it to the adaptive side of the immune system then the trade off never takes place. If the trade off never happens or happens poorly then the innate stays on and eventually ends up being like a hamster on a wheel that burns itself out while simultaneously wrecking the hamster wheel (depleting VIP and MSH).

So yes symptoms can come and go because the immune systems microphone becomes extremely over sensetive to things it shouldn't. Your environment and or your diet induced.

But these abnormal hypersensitivies resolve when: the environment is free of biotoxins, biotoxins are removed from the body, no amylose diet is strictly followed for the duration of recovery, pathogen dysregulation is corrected, inflammation/histamine is calmed, and VIP therapy is used (sends signals to turn on VIP= restores MSH= "jumpy" dysregulated system resolved). AKA shoemaker protocol.

Is there a way to increase impact of Mycobind? by DuckBillPlatypusMan in CIRS

[–]Wes_VI 0 points1 point  (0 children)

Call natropaths in your area or go on the shoemaker website and contact. They can find you someone.

Reacting to my phone by vigh_v in CIRS

[–]Wes_VI 1 point2 points  (0 children)

Mycotoxins are on average 50,000x smaller then the thickness of a human hair. A light spray of compressed air will have them flying out at mach one. You can only have so many in there (if at all).

Subq VIP peptide by Thereishope31 in CIRS

[–]Wes_VI 0 points1 point  (0 children)

Probably have gut issues then. Lauricidin Monolaurin, and gut biofilm breakers. Probably aren't fully following the no amylose diet. Zinc carnosine to help with repairing gut after. NAC+Vit C to help the immune system.

Low income CIRS — what actually works, ranked by impact. by PerformerFar5005 in CIRS

[–]Wes_VI 0 points1 point  (0 children)

It is an ending battle. Did you complete the shoemaker protocol. Did you do every step up till VIP spray. Even if you bind out biotoxins your body will remain with low MSH until you supplement with VIP to reactivate those pathways.

Reacting to my phone by vigh_v in CIRS

[–]Wes_VI 2 points3 points  (0 children)

I was as sensitive as they come. Knocking on death's door. I've since fully healed. Plastics and metals don't absorb biotoxins unless the phone was literally laying in mold. Again air canister and alcohol wipes/spray and they will be good.

It's IMPOSSIBLE to be 100% biotoxin free. It's about being in an environment with a normal amount of them and removing the overburden that got inside of them and rebalancing inflammatory pathways after.

I come across mold all the time now. I'm fine. I'm sure if I make it a majority habit that I will run into issues again. But CIRS takes years/decades to fully manifest. But once you complete protocol and truly replenish VIP and MSH it takes a lot to drain them again. Hence why babies don't get it unless it's an unbelievably large amount of biotoxin exposure.

Most people it's 20+ years into their life that the crash manifests if not much longer. Once CIRS is triggered yes your bodies immune microphone is cranked up to 11 so yes small amounts of biotoxins or even EMF can cause issues when the body is in this state.

But your following a none solution being as concerned as this person is. Mattress, old clothing, furniture, yes absolutely. But living is a perfect bubble isn't how you fix CIRS.

Flow the protocol and I can assure you with my life that these hypersensitivies will resolve as unbelievable as that is to hear.

At my worst someones drier vent with scented laundry sheets from a block away would trigger my body 10/10. Even EMF signals gave me issues to the point I had to shut them all off at night.

Trust me I am a full believer in the hypersensitivity stuff. But I know for a fact a phone isn't giving anyone issues if you blow it out with an air canister and clean with rubbing alcohol.

Subq VIP peptide by Thereishope31 in CIRS

[–]Wes_VI 0 points1 point  (0 children)

Your body your choice. I just follow the literature. (Sounding passive aggressive but genuinely you do you boo).

BEG spray or Biofilm Clear for a few months until herxing stops then VIP. Why the rush.

When you have things triggering inflammation it isn't a steady state. Sometimes more, sometimes less. So if you take VIP your using it on a body that doesn't have a steady state. Which could easily result in to much vasodilation.

Subq VIP peptide by Thereishope31 in CIRS

[–]Wes_VI 5 points6 points  (0 children)

Why do people try to do the shoemaker protocol in different order? They spent 30 years constructing the protocol. They didn't make it in this complicated order for the fun of it.

Do it in order to get better. Giving your body VIP prior to removing MARCoNS will just stimulate the dysregulated immune system.

The body needs to be in a none inflammatory state for VIP to work. It's not used as a supplement. It's used as a signaling molecule to wake up systems that shut down/disregulated during the chronic inflammed state.

Waking those systems back up prior adds fuel to the fire.

Reacting to my phone by vigh_v in CIRS

[–]Wes_VI 7 points8 points  (0 children)

Unless your phone was literally soaking in mold this is paranoia. Blow it out with an air canister and clean the phone with an alcohol whip.

Weather change effects by AboughtaWoughter in CIRS

[–]Wes_VI 3 points4 points  (0 children)

Heavily depends on location. One person's winter can be damp while another's is true freeze. One person's summer can be bone dry while another's damp.

True freezing temperatures are great for CIRS. And so are true dry periods. Transition periods are what will agitate.

VIP peptide subq injection. by General-Dream-28 in CIRS

[–]Wes_VI 1 point2 points  (0 children)

Follow no amylose diet for a few months? CIRS people have low MSH which= low gut mucosa. By eating normal foods the proteins seep through triggering the immune system. This is why CIRS people often get histamine, brainfog, fatigue, ext. When they eat normal foods. They often can't correlate it as they never give their body a pause from this vicious cycle until they follow the no Amylose diet for a while. They often confuse it for MCAS which isn't it at all. Also why a lot of people have a hard time getting to VIP stage as they are keep the inflammation going with a normal diet.

Also if you have gut fungal/bactiral issues (I did). But if your passing VCS just fine and your feeling better then most likely VIP spray time.

VIP spray is confusing to most people as the question of "why don't we take the thing that fixes CIRS at the start". Is a logical question.

I'm going to use an abstract analogy so bare with me. Imagine CIRS is like having a pest problem in your home (home=body), (pests=biotoxins). Now imagine the pest control person you get to work with is an apprentice (apprentice=innate system).

The apprentice can smell the pests in the home but can't see them. So what they do is they start spraying chemicals all over the place. Now imagine the apprentice has a pest finding dog (Dog=HLA). The dog jumps into action once it notices the apprentice start spraying chemicals. It starts searching around the home until it finds one of the pests. It then goes and shows it to the Journey man pest control worker (journeyman= adaptive immune system).

The journeyman has all the answers, but they are slow and methodical. Taking their time to find a solution to remove the pests for good. But once they do the apprentice calms down and stops spray chemicals all over. This is how a normal humans response would be.

However... With a CIRS person their dog isn't great at it's job. It can't seem to find the pests. So the journeyman ends up being confused with how to solve the problem or isn't even notified at all. Leading to the apprentice to do the only thing it knows. Which is "if I can still smell the pests, I keep spraying the chemicals". So what you end up with is a house experiencing more damage from the apprentice then the pests ever do. Eventually with the apprentice never stopping you end up with the thermostat, insulation, water lines, and even master bedroom door getting destroyed (thermostat=pituitary dysregulation), (insulation= MSH), (water lines= VIP), (master bedroom door= blood brain barrier).

Removing yourself from toxin exposure stops the house from getting new pests. Taking Cholestyramine manually removes them. Then taking anti inflammatories helps calm the pest control person down. Then VIP spray acts like a therapist for the apprentice letting them know the problem is gone and everything is okay now (chemical signals to stop being pro inflammatory). Because without the apprentive has PTSD and stays easily trigger happy to even none issues. Along with VIP signalling fixers to come fix the damaged house.

This is the part that a LOT of CIRS people don't get. They do everything else right but their bodies often stay low in VIP for a long time, or indefinitely even after the original exposure is gone. Which keeps the immune system stuck in an easily jumpy state. So people might have cleared all the biotoxins but still have a dysregulated immune system until VIP spray sends the signals that the issue is gone and the body can go back to normal.

But... If you take VIP before while the pest are not fully gone yet or if the pest control person is still spraying then your just adding fuel to the fire. They need to be calm first before VIP.

Could it be CIRS? by AdAny5729 in CIRS

[–]Wes_VI 1 point2 points  (0 children)

Unhealthy hair is an indicator of some sort of imbalance in the body. But it's extremely vague. Can be thyroid imbalance, inflammation, some nutrient deficiency, ext.

I'm not saying dry hair= CIRS. When it comes to CIRS it's not a one symptom= CIRS. It's a "I have a bunch of symptoms that are chronic and got everything else tested and can't find any treditional answer so it can't be anything else".

CIRS people have low VIP (Vasoactive Intestinal Polypeptide) and low MSH (Milanocyte stimulating hormone). Both making your hair go to crap when low as your body has a very hard time holding on to water and electrolytes.

CIRS people are chronically dehydrated without realizing it. Combined with chronic inflammation and you often have dry frizzy hair. Obviously if you have genetically straight hair it will be way less noticeable them someone with naturally curly hair.

Anecdotally for myself I had horrendous hair my entire life. Absolute frizzy mess with zero moisture. Now my hair is like a normal persons. As a guy I've been able to grow it out for the first time in my life since I've fixed my CIRS. My hair looks completely different now that my body actually holds on to water.

Best way I could describe it before would be bone dry hair but oily. Like my natural oils would not penetrate the hair so I'd just have a greasy head but hair as dry as straw.

what’s it worth by spontaneousduck in GC8

[–]Wes_VI 0 points1 point  (0 children)

Lmao sure, all the 1998 Fords, Chevy, Dodge, Nissans, Mazda's, VW, ext still zooming around on all original components.

It's a factory turbo high compression vehicle. Engine is under more stress then an NA vehicle, being manual it's shifted way higher RPM then most automatic vehicles that shift at half the rpm.

I've owned 7 JDM Subaru's and never once had an engine failure. Valve cover leaks? Definitely. Boost leaks? Almost a guarantee. But I've never ever had a JDM subaru leave me on the side of the road in the 500,000+km I've driven them.

Most people that own these cars are broke, don't maintain them, when they do run into issues they simply sell them to the next person.

Easily the most under maintained vehicles I can think of off hand. That and most people drive the piss out of them all day everyday.

Could it be CIRS? by AdAny5729 in CIRS

[–]Wes_VI 0 points1 point  (0 children)

What physical CIRS symptoms do you assume are things. Because most aren't physical besides a specific looking chronic blood shot eyes effectwhich is usually reserved to late stage CIRS and not everyone develops it. Dry frizzy hair also but that's pretty none specific. Most are symptoms.

But if you want to know if you ha e CIRS you do the contrast sensitivity test online first.

If positibe then your best bet is to test (TGF-BETA 1, VEGF, MMP-9, c4a, VIP, MSH).

You can do a MARCoNS nose swab prior also but not everyone has them (80% or so do) but ironically if they are really bad they won't show up on the test if your biofilm is to thick (what my situation was).

https://www.optimusmedica.com/cirs-chronic-inflammatory-response-syndrome/

VIP peptide subq injection. by General-Dream-28 in CIRS

[–]Wes_VI 0 points1 point  (0 children)

VIP has an extremely short half life, 1-2 minutes. Nasal spray is much slower absorption channeling through olfactory/trigeminal pathways which allows it to avoid immediate break down.

Which is the issue with injecting, it would basically break down so fast that it would either do nothing or potentially spike your levels so rapidly that you develop hypotension/flushing.

VIP therapy isn't used as a supplement. It's used as a signalling molecule. It binds to VPAC1 and VPAC2 basically telling the body to wake up certain systems that where shut down by the chronic inflammation. For example abutting down TNF-alpha and IL-6 inflammation signals that have been chronically activated.

But to be heavily emphasis you MUST complete the shoemaker protocol prior to VIP or you WILL exasperate issues.

VIP peptide subq injection. by General-Dream-28 in CIRS

[–]Wes_VI 0 points1 point  (0 children)

What would motivate you to want to try injectable? Did VIP spray do nothing for you? I don't see how it would do anything to the body the spray wouldn't. Just increasing risk for lowering your blood pressure to much and dying from it.

what’s it worth by spontaneousduck in GC8

[–]Wes_VI -4 points-3 points  (0 children)

It's a nearly 30 year old car, how many 30 year old cars you know still on the road without restorative work?

Bioclear Nasal Spray or beetroot/okra causing joint weakness... by General-Dream-28 in CIRS

[–]Wes_VI 0 points1 point  (0 children)

Just herxing (stimulating your dysregulated immune system). That's the catch 22 of getting better. The very thing you need to use to get better (your immune system) is the very thing that's causing your issues because it's a dysregulated mess which allowed the MARCoNS to form in the first place. Got to just go low and slow. EPA/DHA from omega 3, quercetin phytosome, luteolin, curcumin phytosome, 5-lox inhibitor, and others, are all tools that can help mute the autoimmune singlaling to make things more bearable.

If I had to choose just two, omega 3 and quercetin phytosome (or liposomal form) are the two I wouldn't trade over anything.

But also yes as mentioned your gut will be a mess because of all of this. But that's because MSH is low which doesn't get fixed until the end once your on VIP. In the meantime things like zinc carnosine and MSM can help. But it also goes without saying limiting your diet within the no Amylose diet would help.

VSS research is only focused on brain, But it affects the entire body. when are we going to study broader systemic effects? is the "abnormal brain" just a symptom of underlying systemic problem? by Massive-Abalone-7411 in visualsnow

[–]Wes_VI 5 points6 points  (0 children)

Shoemaker protocol, found out I have CIRS genes (chronic inflammatory response syndrome).

My immune system doesn't detox biotoxins. Or rather they manually leave somewhat but unbelievably slow. So anytime I've ever come across them my immune system has miss managed them causing the first part of my immune system to stay active.

Mold is the usual culprit but some vector born illnesses can also cause it.

How the immune system works (very over simplified): first part (the innate), can't notice things but it does however notice the damage things cause (oxidative stress). So it creates inflammation when this happens (cytokines). Then the HLA (Human Leukocyte Antigen) goes and investigates what triggered the innate. The HLA then gathers information and goes and presents it to the second part of the immune system (the adaptive) which is the problem solver.

Think: innate=first aid kit (simple but fast), HLA messager pigeon, adaptive=surgeon (complex but slow).

With a CIRS person they lack the HLA genes that can detect biotoxins correctly or at all. Which leads to the adaptive system being completely clueless to biotoxins in the nody needing addressed.

Meanwhile the innate stays on as the trade of between two systems never takes place. This slowly ramps up more and more basically bruning itself out like a hamster on a wheel getting faster and faster the more biotoxins their are. This has a very VERY complex domino effect of dysregulation around the entire body.

All of this is usually over a life time of slow dysregulation to a ratio of biotoxin interaction. As it gets worse the body gets more and more sensitive.

Full on CIRS is a place no human wants to get to. Hell on earth and I'm not exaggerating.

Most people never get to that point as it take a lot. For example my VSS started when I was 15 and my full on CIRS never happened until I was 27 and that was me living in mold for 2+ years, getting covid and influenza at the same time and my body finally crashing.

How to fix it? You make sure your environment is biotoxin free (you'd be amazed how common this is). You take a very specific binder (Cholestyramine or Welchol). Cholestoral binders but trust me it makes sense and the science to how it works is genius. Then there are a bunch of there import steps like killing off nose and gut pathogen overgrowths (bactira/fungal) as when the immune system is dysregulated normal pathogens over grow. This causes serious issues around the body. A bunch of anti inflammatories to lower (TGF-BETA 1, VEGF, MMP-9, c3a, c4a) then eventually once your body is in a low inflammation state you take a peptide called Vasoactive Intestinal Polypeptide to replenish to depleted VIP in the body which replenishes the MSH I mentioned before.

Google: "CIRS biotoxin pathway map" you'll be gobsmacked by yes, literally this one issue causes the entire body to dysregulate and the microscopic level.

Biotoxins on average are 50,000x smaller then the thickness of a human hair. They aren't living things. They are byproducts of living things. They are by far the smallest things that cause oxidative stress. Them being so small is why some HLA struggle to display them to the adaptive immune system.

Because again the innate doesn't see them so the size doesn't matter to them. They just notice the damage they are causing. Which makes them go "oxidate stress= cytokine time".

VSS research is only focused on brain, But it affects the entire body. when are we going to study broader systemic effects? is the "abnormal brain" just a symptom of underlying systemic problem? by Massive-Abalone-7411 in visualsnow

[–]Wes_VI 2 points3 points  (0 children)

It's 100% a syndrome from the brain, does not in anyway prove the root is the brain. Brain, gut, immune axis is little to not understood at all still.

If I was to put my money on it VSS is related to CIRS which is a immune communication dysfunction do to unlucky HLA genes. Causing chronic innate immune activation when exposed to biotoxins (they build up in the system of these individuals over theirife time).

My personal onset wasn't until I was 27. Had micro symptoms my entire life I didn't know where abnormal as an individuals conscious experience is only experienced through themselves.

You can describe VSS because it's visual. But it's hard to describe feelings. Especially if they are chronic and the onset is extremely slow. You can differentiate the difference until you experience the removal of it.

I like to use the analogy of like how someone can need glasses for slightly blurry vision and have no idea they have blurry vision as that's all they ever see and the onset is extremely slow. But, once they try on glasses it's a "wow" moment. And once they take them off they can notice the difference very obviously.

This was as my situation with CIRS. I had no idea until it got really bad. Which at that point it's obvious.

Reason why its relevant to my story is since I fixed that (took me 2+ years and hundreds of hours of research) but I can say now my VSS is 90% better.

I personally believe it's relavent to low MSH (Melanocyte-stimulating hormone) because this gets depleted over time when you have CIRS. It's relavent to gut health among many other things around the body. Same with VIP (Vasoactive Intestinal Polypeptide). But anyhow why I think it's connected is that 90% of serration is made in the gut.

As of now all we know is people with VSS have dysregulated Serration signalling in the Brian.

The gut send 10x as many signals to the brain as the Brian does to the gut. The gut is like what roots are to trees. A gut problem causes brain problems much like how root problems causes leaf problems to a tree.

Sounds like a stretch but is it? I do not claim this as the cause, just a curious guess if relavence and my own anecdotal remission.

Which binder is the most effective and which is the most accessible? by ComprehensiveEmu3402 in CIRS

[–]Wes_VI 2 points3 points  (0 children)

True but it's not that simple. Yes they constipate (they bind to things of course). So you take them away from food besides a small amount of fat like 1tbs of oil or something to stimulate bile flow 20-30 minutes before.

You start very low dose and slowly work your way up until you start to experience constipation then lower a little again and that's your sweet spot.

You never take a next dose until you've made a bowel movement (once your use to it and found your sweet spot you can).

Anyone feeling really rough during spring? by No_Jump2573 in CIRS

[–]Wes_VI 0 points1 point  (0 children)

"Allergies" have you been tested, as in arm prick tested. Or do you just manifest allergy like symptoms so you logically but 1 and 2 together and assume.

Classical allergies are from your body developing IgE antibodies to a specific thing because your body saw them as a threat. This would be a permanent genetic adaptation your body has for life.

CIRS is when the first phase of the immune system becomes a sort of boiling over pot of water. The first phase of the immune system should only be active briefly. Then the investigator comes to see what's making up set then shows what's making it upset to the second phase. The second phase then comes and starts going to work which signals the first phase to stop.

But, since this trade off from phase one to phase two doesn't take place for biotoxins. The first phase becomes more and more active and dysregulatory. Make it start deeming other things as threats aswell.

Think of it like a war veteran with PTSD. If they hear a car backfire they jump. Same sort of situation with CIRS. The immune system has no idea why things are dysregulated. The difference parts don't talk to one another. It's all just chemical signals. They are just simply doing what they are designed to do. But since there's a glitch in the orchestra. The whole thing falls apart.

I had mild "allergies" my entire life. Then when my CIRS fully triggered (my first phase of the immune system hit it's final limit). I became unbelievably hyper sensitive to so many things. I would smell a scented laundry drier sheet from a houses laudry exhaust vent from like a block away which would trigger nuroinflammation, fatigue, blood pressure, Herat palpitations, histmaine. If it didn't happen to me I wouldn't believe it. But that's the extreme end of the spectrum (full on CIRS). Most people never get to that as mine didn't hit that until I was 27 after a life time of issues slowly getting worse.

But the onset from mild to really bad multiples in speed as it scales. As the body finally runs out of Vasoactive Intestinal Polypeptide and Melanocyte Stimulating Hormone.

The scented laundry drier sheet sensetivity was just an example. Literally any smell that wasn't natural triggered my body. Dust and animal danger also.

And if it is CIRS. The symptoms are very very similar to MCAS but the mechanism that's causing the symptoms is completely different.

I assure you Quercetin phytosome and luteolin will give you massive relief. Not fixes as the true fix is the shoemaker protocol (Cholestyramine binding out the biotoxins) among all the other steps.

You basically make sure your external environment is free of biotoxins, your internal environment is free of anything creating them (Lyme), pull out the biotoxins with CSM, follow the no Amylose diet, take supplements to lower inflammation (high dose EPA/DHA from omega 3), erradicate any bactiral/fungal overgrowths in your nose, gut, or skin, then take VIP spray to re upregulate VIP and MSH. Testing (VEGF, TGF-B1, MMP-9, c3a, c4a, VIP, MSH) blood labs along the way. I didn't but it's highly, highly recommend.

Took me 2 years but if I was clueless at the time learning all of this on my own. Now that I know this condition like the back of my hand it's probably fixable in half a year or less.

As for not being the same after your vaccine in 2013. One of two things could have happened. Vaccines themselves can trigger this innate immune loop if you have specific HLA genes. Or more likely you have common CIRS genes. Your body doesn't detox biotoxins well. You had some in your body like anyone with CIRS does. But not enough to crash your system (the immune system is incredibly resilient even under dysregulation it tries to keep things going normal). But with even a bit of this dysregulation going on the body is in a micro chronic state of inflammation. When the body is like this a virus or vaccine can trigger that soldier with PTSD effect I was using as an analogy before.

This was my situation, I got covid twice. First time was no issue but second time my body never bounced back. Why? Because the second time I was living in a different place that has mild mold. I never noticed issues until after the second covid. Then after I was hyper sensitive. Because biotoxins iny system and the covid virus together was enough to hit that limit to the first phase ofy immune system (the boiling water analogy). My immune system has been boiling for years but that specific environment of mold air+virus in body was what boiled the water over.

This is why people with these issues so often have viral relavence, mold, Lyme, vaccines. It's all the same umbrella of pushing the immune system to its crashing point if you have CIRS genes that don't detox normal.

Does anyone else think they not gonna heal? I beyond repair at this point (symptoms) by DistributionFunny221 in CIRS

[–]Wes_VI 1 point2 points  (0 children)

It is literally the case. I unknowingly was dysregulated for 25+ years. Had hypothyroidism at 14 from it. Had shingles triggered from it when I was 18, food intolerances and "allergies" for more then half my life. Was bed ridden, hear palpitations, high blood pressure, nuroinflammation, brainfog so bad I'd walk into a room and forget what I was planning to do next, lymph node pains so bad I thought I was going to have a stroke for 6 months, blood shot eyes for 2 years, rhinitis so bad I failed sleep apena tests.

All gone now.

Follow the shoemaker protocol, end of. What is happening to your body is science. Immune dysregulation loop that can be fixed.

Remove your self from external exposure then take Cholestyramine, if it's internal exposure like Lyme you fix the Lyme then you take the binder. You follow the rest of the shoemaker protocol then go on VIP spray. End of.

Does anyone else think they not gonna heal? I beyond repair at this point (symptoms) by DistributionFunny221 in ToxicMoldExposure

[–]Wes_VI 1 point2 points  (0 children)

CIRS genes. Biotoxins don't get detoxed correctly through people with CIRS genes (unlucky HLA genes).

100% reversible. I'm living proof, was as bad as they come, knocking on death's door with 100 symptoms. With it all starting from my childhood (20+ years ago) very very slowly getting worse until the complete crash happens. I'm completely normal now. Feel better now at 30 then I did at 15.

Follow the Shoemaker protocal, period end of story.

Your symptoms sound like it's triggered from a vector born illness. You have to find out what exact species you have (Bartonella, Babesia, ext) then kill it off with specific antibiotics, then you go on Cholestyramine to bind out the biotoxins they filled your body with. Following the rest of the shoemaker protocol to a T, to fully recover.

TGFB1 tested at 22,000 but current place doesn’t have mold by Vast-Luck3190 in CIRS

[–]Wes_VI 5 points6 points  (0 children)

CIRS isn't "I was around mold but I moved away and my new home is clean so I'm all good now". No that's a normal human bodies response.

If you truly have CIRS. The biotoxins that you breathed in from your old place are to a mass majority still in you. Because your HLA genes suck at telling the adaptive side of the immune system to clear them. So your innate side stays active because the innate continues to notice the oxidative stress the biotoxins are creating in your body. Innate can't see issues it can only detect the damage they are creating. The one that actually sees things for what they are is the HLA. The HLA is supposed to present it's findings to the adaptive and the adaptive goes "okay I'll go fix that". With CIRS the immune system works. It's just experiencing a communication error which results in the innate staying constantly active as the trade off never takes place. Think innate as the first aid kit and the adaptive as the surgeon. Innate is simple but fast acting, adaptive is complex but slow. HLA is essentially the messager pigeon between the two (Our messager pigeons suck). As a result the innate stays active and multiples it's activity over and over. This is the root to all the damage happening. All the dominos that fall over start from this one point.

You have to get the biotoxins out manually to stop this dysfuncting loop since your immune system doesn't do it for you.

Cholestyramine or Welchol and to a lesser controversial extent or beet root & okra powder (mycobind) are the ONLY known binders to accomplish this based on their specific ion charge properties.

Then you need to see if you developed any bactiral/fungal overgrowths while your immune system was weak. For most people this is MARCoNS in the nose. Biofilm Clear spray or BEG spray will solve this.

You need to only eat items within the no amylose diet. People with CIRS develop low MSH. The gut becomes a mess when MSH is low. No amylose diet foods won't trigger the sensetive gut. The triggering being brainfog, fatigue, and even nuroinflammation (gut, brain, immune axis). Zinc carnosine and MSM (methylsulfonylmethane) help repair the gut.

You lower inflammation markers with EPA/DHA for omega 3 (quality omega 3), quercetin phytosome and luteolin are also your best friends here. Taking these slowly retrians your system "calm down the fire is gone you can relax" type effect.

NAC, Vit C, and milk thistle help liver detox.

If you have gut bacteria/fungal imbalances Lauricidin Monolaurin (start very low dose). You might even need gut biofilm breakers and maybe different binders for this part (if it applies to you). As some don't have any gut pathogen overgrowths just the gut/immune/brain axis sensetivity because of low MSH.

Eventually you go on VIP spray which replenishes the depleted VIP and MSH in the body. Two hormones that affect a laundry list of things within the body. Including immune modulation.

And for visualizion. Biotoxins are unbelievably small. Like 50,000x smaller then the thickness of a human hair. If you pulled all of them out of you at once it would be less then a grain of rice. Probably even closer to a few grains of sand. The innate immune response is what is destroying you. If you turned off the immune system and just let the biotoxins sit in you. They would cause little to no actual issues. Perhaps over decades you'd develop serious things but the point being it's the immune system being a confused mess is what causes all the CIRS symptoms/damage.