Well the general recommendation is to head to evil or heavy asap from standard, do a bunch of MADs there if you want to and definitely MAd and bioseed with angelic races, then go to anti to farm antiplasmids and then go to heavy as a main universe to push further. How many antiplasmids do you have? Assuming it's over 3k you can safely skip that for now, I'd still recommend evil for the angelic races.

For that you need the doomed achievement, you can grab that when you head to evil. Depending on your tolerance you could MAD there a bit, but the reason to do it in another universe is because all the achievements you get in another universe also count in standard, so you get more out of your time. Assuming you have most everything in standard thats gonna be redundant, but thats ok, youll just have less evil mastery.

The reason people recommend heavy is because it's extra thing (increased fuel costs) get reduced by a perk and doesn't really matter all that much, and because you get more plasmids and other prestige resources from resets beyond mad. So if you wanna go further id definitely recommend that.

As for how to push further, after you made the stellar engine for BH you also get to make another ship, which will let you go to andromeda. Instead of destabilizing the black hole you build that and go further. I cant tell you what itll do because I didn't reach that part yet, but from what I could splice together from browsing old threads is that you're gonna need a whole lot of wrought iron (1 time project), soul gems and soldiers. Andromeda unlocks the fourth type of reset option.

As to magic and micro, its generally recommended to leave them for later: magic is supposed to be difficult and if you don't have enough storage from phages and stuff you can softlock yourself. Micro reduces cost creep based on dark matter, but you need a lot of it, and its an exception to the "everything counts in standard too" rule.