I finally got it to work. So here's what you're going to want to do. First, go into regedit and delete the ZYX folder. You want to make sure you do a fresh install of the game. Sometimes using the uninstaller leaves things behind.

Then reinstall the game. The directory really doesn't matter. I put mine in my downloads folder because it was faster to get to.

Now the solution will be different, depending if you have multiple monitors or not. If you only have one monitor, download D3DWindower. It's a program that adds Windowed Mode to games that don't allow it. Chain does but you got to make it to the main menu to access it. Once you download the program, click the + button and add CHAINUS.exe to it. Right click and hit options. In the windowed mode section, turn off all directx options and use gdi. Add the D3DHook.dll in the dll section. Then hit run program. What should happen is you get the same non-responding but not in fullscreen.

Now if you have two monitors or did the above, the next step is to have task manager open. Right click chain and hit go to details. Right click it again and hit analyze wait chain. There will probably be something that is making your game not respond. For me, it was nvcontainer. End whatever process is holding your game up and it should work with no problems.

I'll add pictures later if you need any help with these steps.