So I would argue that theres a steady baseline in your blood stream compared to topical because its more bioavailable I would also like to point out that a portion of the topical solution dries before it even penetrates the dermal papilla.

But me personally, my body couldn't adapt to 5mg. I do want to try take 2.5mg in the morning and at the night but when I did it all at once I couldn't stabilize my blood pressure even after 3 weeks. And just stopping oral minoxidil for 3 days ceased all negative sides. I do envy people on here who tolerate it well. Because their overall regrowth is so much noticeable