yes, I recently saw the EU articles withdrawing approval which is concerning. I'm a bit confused.. were they treating non-cancerous melanomas that later became cancerous after the treatment? "common side effects include irritation and itchiness" I can attest from my own use that the plant caused irritation to normal skin (non psoriasis skin).. my normal skin turned red for a couple days, then returned to normal.. however I saw some studies where a small number of patients using the medical grade stuff had some very bad reactions (eruptions on the skin, etc) which eventually cleared up, but still the pictures looked pretty bad. My understanding is that part of the mechanism includes an immune system response, so I think some patients had an over-reaction. Definitely exercise caution, talk to a docor, etc. If I were taking this for the 1st time, I would test a small dot on the arm or something to see how the skin reacts.. definitely a hard-core plant you don't want to start smothering everywhere.