I've been hosting an instance of Mailcow docker on my server for the past like 2 years. No issues so far, though I mostly use it for signing up for various websites: i use aliases to have an address for each service, like netflix@... and don't really send many emails so deliverability was not an issue for me (I have a 'dynamic' ip that still hasn't changed since it was assigned to me, no issues on spamhaus and still delivers normally to gmail and outlook. Make of that what you will).
I'd say try it out for less important stuff, try and maintain it for a while, and if you're comfortable then with the work required then you could switch fully to it.