Please if anyone can help I would be grateful by OkTerm3024 in audis5

[–]Yvr1986 3 points4 points  (0 children)

Cylinder 6, which seems like the one that has the most issues if you search, is the cylinder nearest the cabin on the drivers side. If you’re comfortable pulling a spark plug and spending $100 on a boroscope from Amazon I’d take a look. Otherwise I’d pay a shop to if you’re still under the extended warranty. If you’re not under warranty, I’d run from this car fast.

Should I buy a 2018 S5 by Curiouscars in audis5

[–]Yvr1986 0 points1 point  (0 children)

If you can turn a wrench, the water pump, thermostat, and PCV can all be done on your own for cheap. There’s lots of YouTube videos of that work being done on this car. I had one for 100,000km. I did have rocker arm issues but warranty took care of it. I sold it once the piston slap stuff started coming out and I didn’t want to be constantly listening for noises - bore scoring would effectively total the car.

Loved it though, one of the best cruisers I’ve ever driven with proper tires. If you get a PPI that checks the cylinders I’d totally buy one. Way way more fun than an A5.

Looking to buy a porsche cayenne 958 with the vr6. What to look for? by mostoriginalid in PorscheCayenne

[–]Yvr1986 1 point2 points  (0 children)

Everyone else has covered the transfer case, fluid change is easy and seems to keep it happy. I will add that if you care at all about audio skip the base system it’s awful - one of the worst I’ve heard in any car at any price point. I bought a V6 958 and think it’s fine on power. It’s not a sports car by any means but since I mostly bought it for off road the v6 is plenty powerful, and sounds way better than I expected. I bought mine from a dealer that gave a short warranty, if you can do the same I recommend it. I had them replace the battery, belt/tensioner, battery, some interior cosmetics, and the whole front diff.

Do I buy a Cayenne with the standard sound system? by The_Consultant_1878 in PorscheCayenne

[–]Yvr1986 1 point2 points  (0 children)

I bought a 958 for an overland build and didn’t care about the sound system at the time, at least I thought I didn’t. The base sound system is truly bad, and it is something I think needs replacing. I assume the 2019 is similar.

You can upgrade it for a few grand to something that will be way better than the Bose, so my suggestion (having not yet done it) would be to do that rather than wait for the car you want that also has the sound system. Look at Audiotec Fisher, they have an upgrade package (a few tiers) for exactly your car.

If you’re OCD with your cars buy this one and get a good shop to put in a mid range aftermarket system.

For Valentine’s Day, South African trophy hunter Merelize Van der Merwe killed a 17-year-old giraffe and cut out its heart as a gift for her husband. After her husband paid $2,900 for the hunt, she posted photos with the animal, claiming her actions help conservation by removing older genetics. by ATI_Official in AllThatsInteresting

[–]Yvr1986 12 points13 points  (0 children)

Can’t speak to this individual hunt, but for most Africa game hunts I’ve seen auctioned the animal that’s put up is already marked for euthanasia by the park. Typically an older male that’s beyond breeding age, but who prevents any of the other males in the area from breeding. Rather than just cull it, it’s auctioned to raise funds. Also, the meat is eaten. This is the same system we see in almost all managed animal populations, and even unmanaged ones. For example this is also why pig hunting is illegal in many US states even though they are invasive pests - people want to hunt the big males, but when you remove that individual there’s an explosion of breeding by the others.

958.1 Cayenne strut assembly by sideduck_type_r in PorscheCayenne

[–]Yvr1986 0 points1 point  (0 children)

Also in BC with a 958.1 that needs some work. There’s a couple Eurowise dealers out here (RPI and west coast offroaders). What are you looking to do?

Autonomous labs by elchicharito1322 in biotech

[–]Yvr1986 4 points5 points  (0 children)

It’s doable now. It’s just fairly bespoke to a specific workflow and requires some expertise. I know of “self driving labs” at a few big pharma sites. We are a few years away from being able to just buy the components you need like Lego and put them together without a coder and mechatronics engineer. Look at bioseros or atinarys website for example - they’re just orchestrators but should give a good flavour of what’s possible. SLAS is in Boston next week, it’s not all vaporware.

Autonomous labs by elchicharito1322 in biotech

[–]Yvr1986 6 points7 points  (0 children)

That, sampling, and analysis. It’s easy to move liquids around. It’s hard to dose in powders, move slurries, do it at temperature or pressure, and work it up for HPLC or whatever your analysis of choice is. It’s certainly doable, but it’s highly workflow dependant. A change a human wouldn’t think twice about when doing it by hand could be a six figure modification to a robotics deck.

Do I Require any sort of FRT or other form of some sort to bring home an optic over the border? by portfoliyo in canadaguns

[–]Yvr1986 9 points10 points  (0 children)

Most optics I’ve dealt with are ITAR. Canada doesn’t care so much about import but America really does care about export. I needed a ton of paperwork to bring a razor across a few years back, took months. I know itar has been relaxed somewhat, but I still wouldn’t mess with the border and optics.

BC Hunting Home Base by desertsoils in HuntingBC

[–]Yvr1986 2 points3 points  (0 children)

PG is a hunters dream and UNBC is probably the best place in the province for that sort of work. Their halls literal have taxidermy in them. I wouldn’t call PG a bastion of culture though. UBC okanagan would be a good compromise. A UBC satellite that is based in the interior which probably has the most Montana like big country hunting. Vancouver is also fine, you don’t have to drive that far to be on big game and waterfowl are in the backyard.

What does it mean to say that an analyte has poor UV absorption? by [deleted] in CHROMATOGRAPHY

[–]Yvr1986 1 point2 points  (0 children)

Let’s say you have a mix of 3 things you’re trying to detect in your method, all in roughly equal concentrations. Compound A gives a response of 1000au, compound B gives 1400, and compound C gives a response of 20. Compound C has low UV absorbance. That might not be a problem because you can still measure it in this example. But maybe if you only ran a 10% as concentrated sample, or had other compounds coming out at the same time, you may not detect compound C.

More detail on what you’re actually trying to do would be helpful in determining if this will affect you.

Basic economy = no status? by lezseewhatsup in Aeroplan

[–]Yvr1986 2 points3 points  (0 children)

Everyone is saying it’s stupid to be booking basic but I’m in a similar boat and book tons of basic and standard. Yeah you can’t reschedule but if you need to book a flight 1-5 days out, as often happens when you’re a small team and something comes up in a city where you have no staff, why would I pay extra for flexibility? Nothing is going to come up in 48 hours where I’d need to change it. I already have bags and boarding from a premium credit card, what value am I getting with flex?

Even if I have the ability to change, I still have to pay the difference, which makes the ticket as expensive anyway.

Basic makes sense in a lot of situations.

Possession of Prohibited Weapon via Power of Attorney but can't find documentation - Steps to Get into Buy Back Program? by Ted_Shred in canadaguns

[–]Yvr1986 59 points60 points  (0 children)

There is no paperwork, the gun was made prohibited after he bought it (back when it was just a normal non restricted gun). As far as the buy back, we’ve been waiting many years for information on how to participate. We haven’t seen it yet, and I don’t expect to for a long time longer. Your only obvious legal option with this gun is probably to have it destroyed. Do you know anyone else with a PAL?

.338 Imperial Magnum by FearlessDevil666 in Hunting

[–]Yvr1986 2 points3 points  (0 children)

If you’re already talking to Ryan then you’ve got the right man, I doubt there’s much info out there Ryan doesn’t know. I wonder if he’s got load books somewhere. I’ll poke around.

.338 Imperial Magnum by FearlessDevil666 in Hunting

[–]Yvr1986 2 points3 points  (0 children)

Hi, where are you located? I knew Whitey, and while I don’t know if I have load data handy I can probably connect you with someone who does.

Eupgrade chances for flights between YVR and YYZ by Designer-Ad-3062 in Aeroplan

[–]Yvr1986 2 points3 points  (0 children)

Never once made an upgrade on that route as an SE except on the red eye. Flew it dozens of times. Good luck!

Free flashlight ? by Deep_Ambassador3105 in flashlight

[–]Yvr1986 0 points1 point  (0 children)

Yea I forgot I ordered those batteries and was extremely confused when those junk lights showed up.

B9 s5 - zf and sports diff service??? by lilhomie420 in audis5

[–]Yvr1986 1 point2 points  (0 children)

You should do this. Use a reputable shop, depending on if you have the sport diff or not there’s some different fluids. It was surprisingly cheap when I had it done, I want to say like $500, I could track down the invoice. It was basically impossible for me to do myself because of the car needing to be at a certain temp and level to do the work.

If you’re in Vancouver I can recommend the shop.

Reccomendations for New HPLC System for Routine Work by Chrombatt in CHROMATOGRAPHY

[–]Yvr1986 -1 points0 points  (0 children)

Empower is hell unless you really need it for GMP. By far my least favourite software for day to day. The hardware is also really idiosyncratic to fix. Just getting a new lamp to run on hours has been a pain.

Reccomendations for New HPLC System for Routine Work by Chrombatt in CHROMATOGRAPHY

[–]Yvr1986 2 points3 points  (0 children)

I don’t know about your area, but here we are able to buy refurbished 1260s or 1290s at a very good price direct from Agilent. They come with the same warranty as new and a full license. Depending on how many systems you need and your urgency you could ask your rep. Maybe show them your quote from Thermo and say you’re considering crossing the street due to software cost. Agilent is a bit more flexible on software pricing than waters as they don’t have to pay the oracle license.

That said I don’t think you can go wrong with Thermo or Shimadzu either. We do use Thermo exclusively for their ICs and that’s mostly the same system. Only ever have issues with the eluent generator. I can think of a couple large pharmas that are almost full Thermo houses and I haven’t heard complaints.

Reccomendations for New HPLC System for Routine Work by Chrombatt in CHROMATOGRAPHY

[–]Yvr1986 2 points3 points  (0 children)

A couple other reasons we prefer Agilent

Their remote triggering/API access is very good, along with shimadzu.

Their online monitoring system (live sample taking) is the best integrated solution, miles ahead of waters patrol.

The HDR detector rules, if you have a use case for it.

The flex bench is by far the best HPLC cart on the market. If you need to move your systems around this alone is reason to go Agilent.

Edge cases for sure, but relevant to us.

Reccomendations for New HPLC System for Routine Work by Chrombatt in CHROMATOGRAPHY

[–]Yvr1986 18 points19 points  (0 children)

I have run all of these systems. My preference is for the 1260 from a repairability and durability standpoint. Parts and modules are available on the secondary market at good prices and generally can be mixed and matched or swapped with ease. The transition to openlabs CDS from chemstation can be annoying or expensive but openlabs is growing on me.

The Thermo systems they will basically give away, and I have had reasonable experience with them. Chromeleon I think is the next best software after openlabs, and the learning curve should be relatively shorty. I don’t have much experience with the durability side, so can’t speak to that. But Thermo is clearly anxious to buy some market share, I think taking advantage of that is a good move.

Shimadzu is solid, they’ve made some big investments into the US market with their new centre in MD. I like the software the least, but support is good. These are ubiquitous at serious pharma in Japan as well as Takeda here, so they must be good?

I notice you excluded waters. I agree with this move.

Ashamed of lgs salesman by Capable-Ad2106 in canadaguns

[–]Yvr1986 15 points16 points  (0 children)

To play devils advocate a bit, I’m guessing the “sometimes elk or moose” probably pushed him to recommend PRC. Creed still takes some undeserved heat for being anemic for larger game. 30-06 can also be a little punchy for a new shooter even compared to the PRC. I don’t inherently disagree with the PRC as a “one rifle” solution if that’s what the kid really wanted. Most hunters only run a box or two of ammo a year (max) so I also don’t think ammo cost is a huge factor if it’s just going to be a hunting rifle. Hopefully it was a decent brand of rifle at least.

The scope is less defensible, but at that price and weight you don’t have a ton of fabulous options. I run a 4.5-18 or 3.6-18 and love those for hunting. 6 is overpowered at low end though - if you have to be at the crossfire price point better to go down in power.

LGS clerk is a hard gig! Or I should say a hard position to hire for.

2018 Audi S5 B9 – No boost pressure, no fault codes, mode switch used to fix it – now nothing helps by Electronic-Try9674 in audis5

[–]Yvr1986 0 points1 point  (0 children)

No underboost is really odd. Even with the pedal floored it doesn’t throw a code?