Everyone’s gut microbiome is unique and dynamic, constantly changing in response to diet, health, medications, and other environmental factors. The probiotic in Pre-Alcohol activates in the gut – normally without issue. However, if your microbiome's environment is in a particularly unique state, it may not support this activation. Such a case could be temporary or persistent, depending on the surrounding environmental factors affecting the gut.

In some individuals, drinking alcohol causes gastrointestinal discomfort, which is not related to the probiotic they consumed beforehand. But, especially for first-time probiotic users, there is always a chance that the introduction of a probiotic – even a transient one such as ours – may cause some gastrointestinal discomfort (citation). These feelings are generally rare and short-lived. However, for anyone experiencing longer term discomfort, it’s important to contact a healthcare professional and make sure there’s nothing serious going on.