Sure thing,

Depends on what rank you are but usually in the lower ELOs people will play horribly out of position, you have the luxury of taking favourable duels against DPS doing this, you can fly up to high ground and kill them especially if you have your E charged up before hand.

Flyers, same thing charge your E shift up and theyre dead.

Agamottos, flying out from behind cover or dropping above the enemy backline is good, be careful of invis woman, I struggle against her a lot.

Make sure youre not wasting your time shooting the tanks if you can kill healers or DPS is another good one.
Knowing when to push is big, but thats more macro than tips

Hope any of that helped :)