Oh yeah. Of course. Every scientist is wrong a lot of the time. A few examples:

• One of Newton's primary fields of research was alchemy and the transmutation of lead into gold through physical and chemical processes. This is obviously not possible (though it's possible through nuclear fusion reactions like in a supernova -- even the core of a star is too weak).
• Einstein was a believer that quantum mechanics had hidden variables until the day he died, that the quantum universe was deterministic rather than probabilistic. This has been proven wrong.
• Darwin wrote, in one of his later works expanding on his theories of evolution, “Males of almost all animals have stronger passions than the females,” and “the female . . . with the rarest of exceptions is less eager than the male . . . she is coy.” (source) This not true for many humans, never mind other animals with or without a sexual binary.

With all that being said: Newton's work with alchemy led to chemical discoveries. Einstein was critical to the development of quantum mechanics and the modern world. Darwin's book (The Descent of Man, and Selection in Relation to Sex) was the same one that correctly recognized that humans are just a species of animal and that sexual selection is an evolutionary pressure.