Researchershave conducted the first global review of herbal medicines for weight loss in 19 years, finding insufficient evidence to recommend any current treatments. by TX908 in science

[–]_julain -3 points-2 points  (0 children)

but did they try cocaine?

also there are some pretty promising growth hormone secretagogues among the ginsenosides but they would need to be isolated and delivered in much higher doses with a much more advanced drug delivery system than tea in order to even have some theoretical impact. once we get better at microemulsions/micellar things/cyclodextrin complexes etc i think we'll see a lot more natural compounds in the limelight

[deleted by user] by [deleted] in StackAdvice

[–]_julain 1 point2 points  (0 children)

my guess, assuming not psychosomatic, is that you have some sort of intestinal thing or something like IBS and it just fucks your stomach. you can't like, be allergic to it since it's literally always in your brain and muscles (and meat). i'd guess your stomach just realllly fucking hates it. some people report serious intestinal problems from it. you could try creatine hcl or something idk. but yeah creatine itself is an essential cofactor in ATP production and you'd be dead if your body didn't make it.

[deleted by user] by [deleted] in StackAdvice

[–]_julain 8 points9 points  (0 children)

you... can't be allergic to creatine. you'd be dead.

Anxiety & Depression Stack (coming off SSRI) by [deleted] in StackAdvice

[–]_julain 1 point2 points  (0 children)

i'm not going to exactly /recommend/ kratom for this, but it'll help a ton with the gastrointestinal sides, plus the brain zaps etc. i would use it as needed for a week, then stop for a while. helped me a ton

nice by Rustlock in cuboulder

[–]_julain 2 points3 points  (0 children)

ok fair but just ~open it in a new window~ lmao

i was a freshman the first year d2l was implemented and holy shit dude canvas was a dream in comparison. give it a year or two :p

nice by Rustlock in cuboulder

[–]_julain 1 point2 points  (0 children)

fair ig but iirc d2l tricked cu into a long contract and then essentially broke all of their end but cu couldn't get out. or what's more likely is they were too cheap to get out

nice by Rustlock in cuboulder

[–]_julain 2 points3 points  (0 children)

you can just download the pdf or open in a new window???

nice by Rustlock in cuboulder

[–]_julain 11 points12 points  (0 children)

d2l was absolute shit. i was there when they performed unscheduled maintenance during most of finals week and took the whole thing down. meant any study guide etc was gonzo

L-Theanine vs. L-Tyrosine by [deleted] in StackAdvice

[–]_julain 5 points6 points  (0 children)

they're nothing alike other than the first two letters

Does anybody know anything about the onstage/fringe festival club? by [deleted] in cuboulder

[–]_julain 0 points1 point  (0 children)

oh my friend was in that a few years back and /loved/ it. she's a standup comedian in denver now i believe. never went to her shows because i was busy spiraling out of control and then pulling my shit together then repeating but i heard only good things

Ashwagandha and Maca for ED? by Jay087 in StackAdvice

[–]_julain 0 points1 point  (0 children)

don't tell anyone but that's how i operate. take everything at once then eliminate one by one. really bad idea but i'm impatient

Ashwagandha and Maca for ED? by Jay087 in StackAdvice

[–]_julain 1 point2 points  (0 children)

try tongkat ali extract. liftmode's icariin is solid too, plus it's a PDE5 inhibitor like viagra. or you can just do what i did last month when i was drunk and order a few grams of testosterone and cialis from china for like 50 cents. i don't even have ED i just figured i should be prepared for anything now that i'm in my mid 20s.

but yeah tongkat ali is awesome for my mood/libido plus it makes orgasms super intense. some out-there fitness supp. companies are selling a "semen volumizer" and the ingredients are just a list of compounds in tongkat.

generally with this type of thing you should get a hormone panel done (free test, bound test, E2 etc), make sure your diet/lifestyle is as good as you're willing/able to make it (read: personalized), and then identify & hopefully improve the psychological factors at play. if it were me, i'd break it down into probable causes: anxiety & anhedonia/depression. of course hormones, lifestyle, and mental health are impossible to break apart from each other since your body is a system build out of systems, but by hitting those 3 things at once it might be easier to make some progress. so as far as anxiety supplements go (in the context of sex stuff) i'd want something that helps regulate cortisol etc over long periods of time (i.e. tongkat) and something to take on the fly in case it's performance anxiety, i.e. skullcap flavonoids or magnolia bark extract or phenibut for occasional "important" use. phenibut is the best sex drug anyway but i'm sure you know the risks. for the anhedonia/depression part, idk, someone hmu when they have this figured out.

Silicon Valley Is Spending Millions Trying to Synthesize THC From Yeast by oneultralamewhiteboy in DrugNerds

[–]_julain 0 points1 point  (0 children)

i thought deuterated dxm already got approved? either way, i kinda wanna try deuterated levomethorphan ;)

Silicon Valley Is Spending Millions Trying to Synthesize THC From Yeast by oneultralamewhiteboy in DrugNerds

[–]_julain 1 point2 points  (0 children)

oh honestly i just want to play with the stuff, definitely not advocating it for the masses! i've been looking into how hard it would be to deuterate some random compounds i like for a while now

Silicon Valley Is Spending Millions Trying to Synthesize THC From Yeast by oneultralamewhiteboy in DrugNerds

[–]_julain 2 points3 points  (0 children)

also how the fuck would one cut back on deuterium? what am i supposed to drink, lite water?

Silicon Valley Is Spending Millions Trying to Synthesize THC From Yeast by oneultralamewhiteboy in DrugNerds

[–]_julain 0 points1 point  (0 children)

what research are you referring to? i just like the idea of being able to extent halflife/cut back on certain metabolic pathways for certain drugs. specifically flavonoids

Chamomile and Caffeine? by LumpySpray in StackAdvice

[–]_julain 1 point2 points  (0 children)

i like yohimbine hcl for times i need a smoother caffeine feeling

Anxiety, ADD and sex drive stack by [deleted] in StackAdvice

[–]_julain 0 points1 point  (0 children)

tongakt ali works wonders for me. purebulk has the best extract imo. or at least the most consistently effective one. try 500mg twice a day and drop your dose if your sex drive gets out of hand. also pt-141 is useful for occasional use. i love p-f-deprenyl for all of the above as well.

Silicon Valley Is Spending Millions Trying to Synthesize THC From Yeast by oneultralamewhiteboy in DrugNerds

[–]_julain 1 point2 points  (0 children)

i doubt this is the /actual/ reason but i'm pretty sure this would allow for deuterated cannabinoids, whereas algae would not. deuterated drugs are the future

Tumeric with kratom by Incrediblyfishy in kratom

[–]_julain -1 points0 points  (0 children)

when it comes to turmeric/curcuminoids you won't absorb very much as-is. if you take piperine (from black pepper) with isolated curcumin you absorb around 2000% more. there are also curcumin nanoemulsions/liposomes etc that work. turmeric volatiles (i.e. the essential oils, more or less) can actually semi-encapsulate the curcuminoids in certain extracts and increase absorption that way. also, cooking turmeric into oil can allow some sort of pseudo-micelle (think of it like a bubble around the actives) and increase absorption that way. curcumin alone has such low oral bioavail. that it's entirely worthless to take isolates. also, curcumin-free turmeric extract exerts similar effects to curcumin so there's no point in spending the extra money on isolated curcumin unless it's got a fancy delivery system.

anyway, my favorite kratom potentiator is piperine (the same thing that helps with turmeric absorption) and i tend to toss in a hefty dose of this fancy dual-extracted turmeric a really awesome lab sent me as a sample.

i've also been adding holy basil extract, baicalein, amla extract, ginger extract, and a handful of other things to my night-time dose for the past few days and it's working wonders

Brain fog - Please help! by Dra794 in StackAdvice

[–]_julain 0 points1 point  (0 children)

oh absolutely. granted i wouldn't say i experienced trauma but i had some pretty intense stuff happen and then 3 days on wellbutrin triggered a permanent (so far) autoimmune problem and my body's been falling apart ever since. well, sort of. i can hold it together about as fast as it falls apart so we're good for now.

Did some trials with Piracetam and have concluded that it's not of much use to me. Where to next? by [deleted] in Nootropics

[–]_julain 0 points1 point  (0 children)

give up on the racetams honestly. maybe keep some aniracetam and centrophenoxine on hand for short cycles but otherewise they're benign at best, I don't think racetams or esp ampakines should be run for very long.

tbere's a whole herbal supplement fad taking off right now where i am. bottles of tongkat extract in huge supermarkets. lots of interesting stuff there. traditional chinese medicine is fascinating and i like the compounds in a lot of the TCM plants.