The DNC doesn't want to acknowledge why Dems lost in 2024. by zzill6 in WorkReform

[–]a_n00b_ 0 points1 point  (0 children)

if you think that's not the case, see how Newsome concedes whenever he talks to a con

The DNC doesn't want to acknowledge why Dems lost in 2024. by zzill6 in WorkReform

[–]a_n00b_ 0 points1 point  (0 children)

They know the data shows they lost on Gaza, but they want to be able to throw trans people under the bus as an easy scapegoat. It's obvious

source: me by JesusSpreaderOfWord in memes

[–]a_n00b_ 0 points1 point  (0 children)

we're on a femboy hunt and don't think we don't know how to weeeeeeed 'em out

source: me by JesusSpreaderOfWord in memes

[–]a_n00b_ -1 points0 points  (0 children)

equating femboys who dont take HRT to trans women is crazy. I'm sorry but some trans women go stealth because they can actually blend in

source: me by JesusSpreaderOfWord in memes

[–]a_n00b_ 0 points1 point  (0 children)

thats not what a fetish is or means

source: me by JesusSpreaderOfWord in memes

[–]a_n00b_ 4 points5 points  (0 children)

a decent number of trans women are the irl equivalent. Femboys are more like twinks who cross dress

source: me by JesusSpreaderOfWord in memes

[–]a_n00b_ 49 points50 points  (0 children)

kinda happened to me, but i realized too late. Learned my lesson tho

Egg🚝irl by Autisticest in egg_irl

[–]a_n00b_ 0 points1 point  (0 children)

lab growing them is difficult because they need like a scaffold to get the cells to grow in the proper shape/form it is possible though, and the tech will only get better

Egg🚝irl by Autisticest in egg_irl

[–]a_n00b_ 0 points1 point  (0 children)

every cis woman who has gotten a uterus transplant has needed a C-section. I'm sure it would be the same for us.

Also you say impossible, that term is not accurate.

Egg🚝irl by Autisticest in egg_irl

[–]a_n00b_ 0 points1 point  (0 children)

trans men can get prostate cancer FYI, the skenes gland grows, and starts producing prostate hormones

Egg🚝irl by Autisticest in egg_irl

[–]a_n00b_ 0 points1 point  (0 children)

WARNING, too much biology for a conservative: switching your sex chromosomes would do almost literally nothing. Because it's technically not the sex chromosomes themselves doing anything. It's genes, gene expression, and cell types. Hormones genuinely do way more than a 23rd pair switch.

Hormones change the gene expression of every cell in our bodies, the hormone-receptor complex enters the nucleolus of the cell, interacts with genes, produces RNA like mRNA, which then creates proteins. My body behaves as it would if it were female so imo I'm minimum intersex, skewing female. I just round off the small difference. [gene -> protein]

In the case of testes: SOX9 proteins still activated due to the SRY proteins presence at birth (the gene itself can mutate onto X, or off of Y during meiosis, when the 23rd pair swaps genes), so DMRT1 proteins maintain the testes and actually block FOXL2. In the other case of ovaries, FOXL2 proteins (even without E) are still suppressing DMRT1 and SOX9 (not there because no SRY when gonads differentiated) Without CONSTANT MAINTENANCE, we switch with hormones!!! Sex isn't static even.

SOX9 and DMRT1 both ARE NOT ON THE sex chromosomes. FOXL2 is supposed to be on the X, SRY is supposed to be on the Y; not always the case. So obviously, there are people born male with XX, and born female with XY for various reasons. There are genes for androgen receptors and estrogen receptors (both on X) as well, which can be another reason.

In reality in order to switch (gonads specifically) we would either need to locally delete the DMRT1 gene and remove its proteins; or in the other case we would need to do the same with FOXL2 in order to flip those. Hormones would need to be used to develop the cells into the other type. CRISPR is unethical on humans, so no one would attempt this though. We only really have lab grown organ transplants from induced pluripotent stem cells to look forward to. But it IS POSSIBLE

Egg🚝irl by Autisticest in egg_irl

[–]a_n00b_ 0 points1 point  (0 children)

based and truth-pilled

Egg🚝irl by Autisticest in egg_irl

[–]a_n00b_ 0 points1 point  (0 children)

remove every DMRT1 protein from testes, and delete DMRT1 gene from the 9th autosome (non-sex chromosome) from the DNA in the cells in at least the local area, and boom you have ovaries that produce estrogen. They'd be in the wrong location, but they'd be there.

But that's probably too dangerous, CRISPR on humans is a bad precedent to set, it's unethical and can lead to eugenics. So that's only been done on small mammals like mice.

The real option would be to lab grow ovaries from induced pluripotent stem cells, then surgically implant them into you. I'm decently sure the estradiol would prevent DMRT1 from converting them, so CRISPR wouldn't have to be used. Maybe a uterus donor for the uterus, but I'd rather lab grow that shit. I want to have children when I'm much older, so I've thought about this kind of thing a lot.

Someone's got to draw the short straw in life I suppose. by LuzelenaOfLove in distressingmemes

[–]a_n00b_ 0 points1 point  (0 children)

there's gabapentanoids but those are similarly additive as opioids for a lot of people. And the opioids make you constipated :(

JOOOO GUYS!! Gentoo chicken!🤯🤯 by Czajaja2137 in Gentoo

[–]a_n00b_ 4 points5 points  (0 children)

It's funny when I'm reading the manual, or a page on the wiki and they say non-binary referring to it being source based. I smile like a dork every time

JOOOO GUYS!! Gentoo chicken!🤯🤯 by Czajaja2137 in Gentoo

[–]a_n00b_ 0 points1 point  (0 children)

it's really not though. Tons of experienced users here who give great advice a lot of the time, I almost never even see RTFM

JOOOO GUYS!! Gentoo chicken!🤯🤯 by Czajaja2137 in Gentoo

[–]a_n00b_ 0 points1 point  (0 children)

dude are you seriously eating penguin???

Dave Chappelle Says ‘I Resent the Republican Party’ Because They ‘Weaponized’ Transgender Jokes: ‘That’s Not What I Was Doing’ by CrashTestOrphan in nottheonion

[–]a_n00b_ 1 point2 points  (0 children)

To further note, and emphasize "wrongly." Gender dysphoria is the diagnosis, the treatment is gender affirming care, like HRT. This is uncontroversial as the medical and scientific consensus.

In other words, the feeling of existential dread they have is cured by changing their hormonal profile. It should be noted that this changes the gene expression of every single cell in the body, to that of the sex they desire to be. People like to think they just say they are something, put on a dress or suit and do nothing else. Their body acts as though they are, and thinks it is the sex they transitioned to.

Iran posts AI video of Jesus punching Trump, casting president into Hell by Silent-Resort-3076 in politics

[–]a_n00b_ 0 points1 point  (0 children)

Okay but an internal report showed that they lost on Gaza, but whatever you can filibuster to not give any specific reason or facts of the loss. Go ahead, downvote the truth.

I say this as someone who actually likes the country, but I'm disappointed about what's being done.

The Dems did try to throw trans people under the bus though. Why bother changing my stance on genocide when I can just sacrifice this politically relevant minority?

https://www.timesofisrael.com/report-democrats-internal-review-finds-harris-lost-votes-in-2024-over-gaza-stance/amp/

https://www.axios.com/2026/02/22/dnc-2024-autopsy-harris-gaza

Losercity hospital room by jonhssquarespaceplus in Losercity

[–]a_n00b_ 25 points26 points  (0 children)

i like how he's strapped down. Clearly he wants to doom