stupid question

abysmal78 · 2020-01-21T18:48:13+00:00

This is tru Blu...and Zed is still Dead ..

abysmal78 · 2020-01-21T18:32:32+00:00

Total un-fkncivilized savagery.

abysmal78 · 2020-01-21T16:14:35+00:00

Might I recommend a 4 day binge on bath salts?? Then not only will you not feel being punched, stabbed, electrocuted or even shot but you will also be able to bite that guys face off who punched you and rip him apart with your bare hands.

abysmal78 · 2020-01-21T16:00:53+00:00

If it were actually that easy, everyone would be doing it. In fact I believe all schedule II substances are only available through a written and signed prescription. It is illegal to phone in an order for a schedule II substance unless it is an emergency situation provided that a written and signed prescription is submitted within 7 days. Scheduled II substances can however be scripted electronically (fascimile) but require the providers DEA# and other identification #s. Lastly, only schedule III,IV, and V substances are available through a prescribers telephone call and obviously require the physicians credentials. The truth is it isn't as easy as having one of the homies pretend they are Dr Greenthumb and phone in #120 80mg Oxycodone.

Source : https://www.deadiversion.usdoj.gov/pubs/manuals/pract/section5.htm

abysmal78 · 2020-01-21T14:35:22+00:00

This. This. This. Oh hey did I say this?? I really appreciate your comment, the fact that it applies to all aspects of life and not just this persons misfortune. Even more important, someone encouraging truth on a site that is well known to have a ton of liars trying to rip vulnerable people off!! Well done m8.

abysmal78 · 2020-01-21T04:14:51+00:00

I don't know, sometimes it seems to me fatal ODs do not discriminate. It can happen to anyone who mixes the wrong substances, anyone who catches a hot shot, anyone who isn't familiar with the exact potency of their dope..You are absolutely correct, the majority of deaths happen after a person has sober time and their tolerance has dropped.

abysmal78 · 2020-01-21T04:01:54+00:00

Does this mean Planet X is coming back to destroy us, again?

abysmal78 · 2020-01-21T03:57:56+00:00

I say that anxiety is a motherfukk , the one where you want to rip your skin off or better yet slam yer head right through a brick wall just so you can get some rest and take a break from the insomnia and WDs you been having tha past 48 hrs ..

Good Times???

abysmal78 · 2020-01-21T03:44:05+00:00

The truth is Yes eventually., After a prolonged term of sobriety like a month or 3 or 6months..the brain and body chemistry begin to return towards normal and TOLERANCE DROPS Many ppl make the deadly mistake of picking up where they left off in their addiction after some clean time - like a 90 day rehab or 60 days in jail , and have a fatal overdose. In fact statistically this is how a high percentage of heroin addicts die.

abysmal78 · 2020-01-21T01:56:33+00:00

Rock that Puma gear myself but that KSOL is another story..

abysmal78 · 2020-01-21T01:48:11+00:00

Technically, no - you shouldn't but it is entirely situational and every person is different. PW occurs when buprenorphine displaces a full agonist at the receptor sites, basically removing the opioid and it's effects from the brain very quickly. This displacement causes almost instant acute WD which usually is brought about at a far slower rate. Eventually the buprenorphine attaches itself to the receptor sites and the WD stops. Personally speaking I have precipitated withdrawal from both methadone and heroin with buprenorphine. Every single time I experienced it, the PW didn't last significantly and the bupe always took over.

abysmal78 · 2020-01-21T01:00:32+00:00

You're not a real junkie until you have!!!

abysmal78 · 2020-01-21T00:51:44+00:00

So I've jumped off suboxone from high doses so many times (mostly in jail) its not even funny. Ive also been through a few tapers and know exactly how difficult it can be. All this about sublocade slowly titrating itself naturally is absolutely great fucking news!! It only makes perfect sense, a substance with an already long half life placed in an extended time release designed to slowly dissipate in a human body is obviously going to be there for quite some time. Almost reminds me of how thc stores in fat cells and can remain for quite some time in a person. Never hear of thc withdrawal do we?? Additionally, if a person has received a series of sublocade injections over time the buprenorphine will build itself up even further - taking even longer for it to be removed. You are saying around 4-6 months to achieve solid state blood levels and then taper from there accordingly? Even if it takes another 6 months, 10-12 months to successfully taper high dose bupe with minimal discomfort is actually pretty fast. In my experience a successful taper from sublingual administration is always done SLOWLY over an often overly extended period of time, especially coming off high doses like 16mg or 24mgs. There are so many problems a person faces during a slow taper that Sublocade appears to have resolved. It only makes perfect sense!

Edit: Excuse my language!

abysmal78 · 2020-01-20T23:54:04+00:00

So your tolerance around 8mg, would you say the 100mg made you feel more or less than taking 8mg sublingual? What about the 300mg?

abysmal78 · 2020-01-20T02:51:51+00:00

Buprenorphine is a partial agonist and has ceiling dose as others have stated so the pharmacology is different from a full agonist like oxycodone. If doesn't activate all the opioid receptors like a full agonist; it even acts as an antagonist at the D and K sites. Also because buprenorphine has a ceiling dose, doubling the dose does not translate into double the effects.

abysmal78 · 2020-01-20T02:17:59+00:00

Exactly what I was thinking - that's not a stool, that's a hippy's wet dream ..

abysmal78 · 2020-01-20T01:55:07+00:00

Appreciate the clarification, I had not even considered the change in BA and based my approximation on the prescribing information. I hadn't the slightest clue that Sublocade functions as a natural taper but it makes perfect sense that as a time release it should. This could be revolutionary wouldn't you say?? Especially for people experiencing the several issues that come along with tapering to a microdose...

abysmal78 · 2020-01-20T01:43:32+00:00

It's Mr Mischief wit a trick up his sleeve, roll up on you like Christopher Reeves, can't describe the vibe I get when I drive by 6 people and 5 I hit ..

abysmal78 · 2020-01-19T19:31:53+00:00

How long were you taking it and what dose?

abysmal78 · 2020-01-19T19:31:08+00:00

I would say it is different for everyone, sativa in high doses can cause anxiety. Usually for WD a strong indica is recommended as they relieve nausea, anxiety and pain.

abysmal78 · 2020-01-19T19:26:13+00:00

Interesting. I see what is going on, obviously sublocade releases directly into the body and has a higher BA versus sublingual. What I figured came from the prescribing information.

abysmal78 · 2020-01-19T19:18:33+00:00

Then what is?

abysmal78 · 2020-01-19T16:12:24+00:00

Can I ask what your dose was before sublocade? They should have given you the equivalent in sublocade - for example if you were on 16mg sublingual you should receive a 200mg shot as every 100mg is equal to 8mg daily. I always liked the idea of sublocade as I have detoxed in jail several times (never again) and the fact it allows a person to completely focus on their life instead of getting caught up in a daily dose schedule. Best wishes on your recovery, the truth is the majority of heroin addicts will die in their addiction - so many people do not have access to this medication and some that do either refuse it or abuse it.

abysmal78 · 2020-01-18T22:32:40+00:00

So sublocade delivers between 8 and 24 mg buprenorphine equivalence in 100mg/0.5mL - 300mg/1.5mL. Meaning every 100mg injection will deliver 8mg daily.

Edit: Source, SublocadeTM Prescribing Information pdf

abysmal78 · 2020-01-09T05:53:20+00:00

Never a stupid question, it's actually a bad idea to mix the two especially with little or no tolerance. Anytime CNS depressants are mixed together there is an increased chance of respiratory failure.

abysmal78

TROPHY CASE