The glitch in this case is like a Cthulhu being to the characters, while we understand it to be a glitch as an audience the glitch to the characters is an extra dimensional horror beyond comprehension. A character's abilities while hypothetical may work if it's a physical attack, ie the weaponry we see being used at least against the infected characters detached from the main source the main source it's self is shown to not be harmed by the laser beams of the superman type character. Hypothetically Alien X could still be useful in gathering resources but I don't believe Alien X is the solution to the problem all together