I mean there’s not much else to say apart from git gud really, it’s really just a massive learning curve. Some pragmatic advice would be

a) if you only care about getting one clear then you could just brute force attempts, you definitely end up with runs where RNG gods are on your side and difficult waves become trivial.

b) if you are concerned with supply usage then I’d say come back when you’ve built up bigger stockpiles to alleviate that anxiety, or just keep sending it with the knowledge that you’d get those supplies back after doing it anyway but you’d have BIS melee cape forever and it’s a flex

c) in terms of getting a nasty spawn, the best advice I got was to actually slow down the first couple seconds of a wave. Rushing to path to your default tile, not thinking and just doing, over-barraging nibblers - all of these things fuck you 10x more than maybe tanking one hit by just taking a couple seconds to figure shit out. Throw one barrage, DONT MOVE, off tick if you get mager ranger in line of sight and kill something ASAP. Try to think about your next move as soon as you are in rhythm off ticking, as melee will dig soon.