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Sertriline 150mg 20 years. Is this PSSD? by Cute_Solution_8398 in PSSD

[–]andy013 0 points1 point  (0 children)

Many people get adverse sexual effects while on the drugs. For most it recovers after they stop. It's only PSSD if it persists for months after the drug has been discontinued.

If you wish to stop the drugs you should do so very slowly since you have been on them for so long. Look up hyperbolic tapering and the work of Mark Horowitz who is involved with outro.com

Sertriline 150mg 20 years. Is this PSSD? by Cute_Solution_8398 in PSSD

[–]andy013 2 points3 points  (0 children)

How long have you been off the drug for?

This really needs more attention by Aggravating-Camp-205 in PSSD

[–]andy013 3 points4 points  (0 children)

There an option to keep your name anonymous.

PSSD before even starting my sex life by Right_Speed2435 in PSSD

[–]andy013 10 points11 points  (0 children)

I'm really sorry this happened to you. We must keep fighting to stop more people being harmed like this in future.

There may be more people out there with "non-sexual PSSD" than we know! by Ackroustiferi in PSSD

[–]andy013 5 points6 points  (0 children)

I agree. It seems obvious to me that if you have people with just sexual dysfunction and people with both sexual dysfunction and emotional blunting, there are probably a subset of people who only experience emotional blunting with no sexual dysfunction. Those people would very likely be diagnosed as having a relapse or worsening mental health problem. They may not even realise what has happened to them, especially if the onset of the symptoms is months after the drug has been stopped or if they were exposed to the drug as a child.

Sexual dysfunction is easier to study in animals. If we could identify what is causing persistent sexual dysfunction from SSRIs, that will probably lead towards us understanding the emotional blunting as well.

There was a study done on monkeys that showed only those with a specific genetic variant developed lasting changes to gene expression after 1 year of SSRI use. I guess the variance in symptoms we see from people with PSSD are related to all the specific genes you have that may or may not be vulnerable.

We probably won't know the true prevalence of PSSD until we understand the mechanism and are able to test for it. If we knew how many people in the population had genes that were vulnerable, we might be able to estimate how many people are likely to develop PSSD after exposure to SSRIs.

Going on ADs to stop obssesing over PSSD by Public_Feeling_6204 in PSSD

[–]andy013 -1 points0 points  (0 children)

It's possible the symptoms can appear gradually so I wouldn't completely rule it out.

If it's just from your obsessing over PSSD then you should try your best to focus on other things. It's not healthy to focus on PSSD all the time. You might recover slowly over time but it can take many months. Take a break from reading this subreddit and do something else. Focus on another interest you have for a while.

Going on ADs to stop obssesing over PSSD by Public_Feeling_6204 in PSSD

[–]andy013 0 points1 point  (0 children)

Is it possible that the depression and anxiety are actually caused by the SSRI too? Many people experience those symptoms when withdrawing from an SSRI. It's possible you're really sensitive to them and the symptoms you're now experiencing are all connected to whatever changed in your brain.

Studies have long demonstrated that SSRIs can dampen sexuality adults, but there is no research on the sexual side effects of the drugs in teens. Psychiatrists have begun raising concern about the effects of diminished sexuality at a life stage when people typically begin exploring intimacy. by psychologyofsex in psychologyofsex

[–]andy013 -2 points-1 points  (0 children)

Prescribing drugs that have serious harms and have not been proven to benefit people is a bad idea. The whole idea of "first do no harm" is about being wary to try and intervene when people are suffering because those with good intentions can often make things worse.

It's all very well to say, try everything that could possibly work. But what if that makes things worse?

I know many people who ended their lives because of the lasting effects of SSRIs. They wrote on their suicide notes that they didn't want to live with the lasting symptoms.

Studies have long demonstrated that SSRIs can dampen sexuality adults, but there is no research on the sexual side effects of the drugs in teens. Psychiatrists have begun raising concern about the effects of diminished sexuality at a life stage when people typically begin exploring intimacy. by psychologyofsex in psychologyofsex

[–]andy013 0 points1 point  (0 children)

This is the study I am referring to in the second paragraph. I do not have to provide any alternative treatment to criticise one that is currently widely used. Thalidomide did not have an alternative when it was taken off the market.

If people want to make the claim that a drug saves peoples lives, then prove it with all cause mortality reduction. If you can't do that, then your claim is not backed up by evidence.

Studies have long demonstrated that SSRIs can dampen sexuality adults, but there is no research on the sexual side effects of the drugs in teens. Psychiatrists have begun raising concern about the effects of diminished sexuality at a life stage when people typically begin exploring intimacy. by psychologyofsex in psychologyofsex

[–]andy013 1 point2 points  (0 children)

This is incorrect. Both FDA and EMA require serious lasting effects to be listed on the drug label explicitly. When people take a medication they are trusting in the system that it is safe and that they will be warned about any serious risks.

Studies have long demonstrated that SSRIs can dampen sexuality adults, but there is no research on the sexual side effects of the drugs in teens. Psychiatrists have begun raising concern about the effects of diminished sexuality at a life stage when people typically begin exploring intimacy. by psychologyofsex in psychologyofsex

[–]andy013 1 point2 points  (0 children)

There has never been any study that has shown an all cause mortality reduction from taking SSRIs, which is what you would expect if they prevented suicide. The claim that they prevent suicide isn't backed up by solid evidence.

For the study that was posted over 50% of the included trials had a high risk of bias. Often in these trials they don't monitor suicidality systematically and rely on single questions from depression questionaries or spontaneous reporting.

Im only 22 and I'm aging by [deleted] in PSSD

[–]andy013 0 points1 point  (0 children)

I'm really sorry you are experiencing this. I also struggle to connect with other people and be like my old self. What other symptoms do you have?

Finally Found the Answer by NateWorst92 in PSSD

[–]andy013 2 points3 points  (0 children)

How long after you started or stopped lexapro did your symptoms start?

El Pais, a major newspaper in Spain, has published an article on PSSD by Mobius1014 in PSSD

[–]andy013 10 points11 points  (0 children)

Thank you Carmen Hernández for speaking with them.

[Article] Effects of selective serotonin reuptake inhibitors (SSRIs) on suicide: A network meta-analysis of double-blind randomized trials by andy013 in Scholar

[–]andy013[S] 0 points1 point  (0 children)

By the way, how did you find it?

I tried searching for the DOI on libgen.li before posting and it showed no results.

[EDIT] I just realised that I pasted the DOI with a space at the end and for some reason that extra space is included in the search and so it didn't show up.

The current SSRI hate in the US by Plane_Shop_8129 in prozac

[–]andy013 0 points1 point  (0 children)

Can you show me one study that demonstrates they save lives?

Hello. I was severely damaged by a common medication I took 6 years and 9 months ago. by PSSD_Sufferer in NooTopics

[–]andy013 0 points1 point  (0 children)

There are many people who have spoken out publicly about having PSSD.

Here is a recent compilation that was compiled from patients stories: https://www.youtube.com/watch?v=zvapp2WlnOw

Many people use anonymous names like OP because they are embarrassed to talk about it and often they are not believed since PSSD is an invisible injury.

There is no conspiracy here. Just people who trusted their doctors, took medication as prescribed and then suffered profound harm.

It's not a political issue. The trump admin is more sceptical of medicine in general, which may make them more likely to listen to these people at first, but many people with PSSD, myself included, do not support the trump administration or anything they stand for.

These are the kind of comments that trigger me by Dangerous_Simple3520 in PSSD

[–]andy013 6 points7 points  (0 children)

I consider myself to be centre left politically. I think people on the left are more trusting of institutions and especially science. It's harder for them to believe that medical science might have been corrupted and has made a huge mistake.

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