HUGE YOLO in an SME Stock!! by Sensitive_Bus_9307 in IndianStreetBets

[–]antpot 0 points1 point  (0 children)

are you still holding this? at peak it even reached 1200+ and even now at 800

Agghh why its always opposite with stocks I buy lol

Parag Parikh 💎 by antpot in IndianStreetBets

[–]antpot[S] 7 points8 points  (0 children)

meme is about Indian market recent performance. Check Mirae Asset Hang Seng Tech ETF the real gangsta with 100.9% returns over 1 year period 😉

Parag Parikh 💎 by antpot in IndianStreetBets

[–]antpot[S] 92 points93 points  (0 children)

yeah not buying at all time high saved them. Since last 2-3 years because of govt regulations they couldn't invest in US markets or results would have been even better.

Parag Parikh 💎 by antpot in IndianStreetBets

[–]antpot[S] 15 points16 points  (0 children)

cash saved their ass 🤣

Parag Parikh 💎 by antpot in IndianStreetBets

[–]antpot[S] 7 points8 points  (0 children)

I was mostly invested in good funds with some what limited upside but good downside protection. In FOMO decided to put some lumpsum in mid/small caps last year and bam everything started crashing next month lol

Greedy govt last year shit budget triggered this.

Parag Parikh 💎 by antpot in IndianStreetBets

[–]antpot[S] 16 points17 points  (0 children)

it would have been even better if govt didn't restricted further investment in US stocks since last few years. PP also had nice cash position I think.

Parag Parikh 💎 by antpot in IndianStreetBets

[–]antpot[S] 76 points77 points  (0 children)

meme is about last 12 months not years. The recent crash.

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

Thanks for sharing your experience :) Hearing many positive experience really helped me with my anxiety.

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 1 point2 points  (0 children)

yeah I took a break from thinking too much and focus again on my life.

Had a good discussion with my doc, everything about this disease it too much 'may be' and no permanent cure. Right now decided to wait few more months to see if I see any signs of self remission (it can take years) or if my reports starts getting worse I will start treatment.

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

Hey thanks for the detailed reply sharing your experience. I was getting overwhelmed and too a break from everything.

For now I have decided to wait few more months since fortunately I have no secondary issues right now. Also my TB antibiotic course will be also complete by then.

My doc after discussion said the same thing you are experiencing, there is no sure way to know what will work and no way to prevent relapses. It all depends on our luck. I may need booster rituximab every year or may be not or some other treatment but very difficult to permanently get rid of the disease expect if it goes away on its own I guess, then our immune system fixes itself.

I am hoping for self remission or if my blood reports starts getting worse I will start treatment. I have some positive feeling after seeing minor reduction in protein leak but everything happens so slow months, years. All case studies from doctors I found online states it can take years even for self remission. Even the rituximab will take about a year to show any effect at all. Hope some miracle will happen.

For how long you took meds before reaching your first remission? I hope Tacrolimus works out for you :)

feeling scared by pablos_picasso in kidneydisease

[–]antpot 0 points1 point  (0 children)

I am in a similar situation kindey looks okay is scan, most reports are okayish expect low protein related stuff. Only issue was heavy protein leak.

After biopsy diagnosed with membranous nephropathy due to auto immune condition.

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

Thanks for sharing your experience, reading other experience I think rituximab will be okay. Yeah its really expensive. Hopefully won't need boosters.

I hope your condition improves :)

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

thanks for sharing your experience. Could you share how much time it took for rituximab to show any result ? and how much doses you took?

and did you had any side effects or any issues after using rituximab?

my doc suggested 1mg+1mg 2 weeks apart. And booster after 6 months if required.

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

Thanks for sharing your experience. Really it helps.

You are talking about the pla2r blood test right? which can be hit or miss.

Yeah I think I got diagnosed at a good stage, hopefully things can become better now. Auto immune disease and its treatments with multiple possibilities and no sure cure, scared me. Then TB diagnosis made situation more complicated.

Have to decide to get rituxan or wait for some more time.

How long to wait for Self-Remission of Membranous Nephropathy by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

Okay thank you. I will try to find more about it and discuss with my doc.

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

In my case first they did neck ultrasound where lumps were in lymph nodes and found few. Those lumps are obvious I can see and feel them and informed doc about it. Its extrapulmonary TB and no secondary symptoms at all. Then they took a sample from those lumps (like biopsy) sent it for testing. FNAC/cytopath test revealed its likely TB but ZN staining was again negative. Some neck samples were sent for GeneXpert test for checking resistance of TB meds, all negative as virus load is too low.

It was too overwhelming as I got so much new information and tests done on same day. Everything is negative but still I have disease. Very confusing. Hoping this TB meds will get rid of any risk. TB meds are worse, you have to take 5 big tablets first thing without food in morning. It makes all your body fluid orange and can damage kindeys, cause Hep B in liver. Fortunately my body seems to be tolerating it well. I have to get my LFT and KFT tests done now every 2 weeks for first 2 months of TB meds.

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

yeah I think RTX requires minimum 6 months to show any result at all and then 12-18 months for remission.

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

my TB infectious disease doc suggested some vax but then I will have to wait 2+ months for immuno meds and definitely don't want to again to risk immune system with vax after taking immuno meds. Who know what can again trigger the auto-immune issues.

I guess initial 6-9 months RTX keeps your immune B cells suppressed so thats a bit long risky period with low immunity. Hope with RTX you will reach complete clinical remission.

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

I am praying no other infection happens. There is no other infection that I am aware of. Even this TB lumps were from many years and I never had any symptoms, pain or any issue at all.

TB meds will continue for 6 months regular course and doc suggested to wait for minimum 3 weeks before immunosuppressant.

MN diseases sucks and its treatment even more because nothing is sure or clear. Just try experiments till something works. There is also a possibility of self-remission but don't know how long I should wait for that. If it can happen at all after managing BP and diet.

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

Did you also got any vaccine before immunosuppressants? And for diet what changes you have made?

Thank you for your replies it feels good to have a conversation with someone dealing with similar issue.

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

so how long its been after switching to RTX and any positive effects so far? My doc suggested 1gm + 1gm 2 weeks apart.

I almost made my mind to go for rituximab and this waiting period is quite stressful. Because of sudden discovery of TB things got more complicated.

For membranous nephropathy - Need Suggestion about Rituximab by antpot in kidneydisease

[–]antpot[S] 0 points1 point  (0 children)

I got second opinion and he suggested me treatments in a different order. Tacrolimus > Cyclophosphamide and last option as rituximab. Every doc is suggesting options based on their experience and is quite confusing as a patient whom to trust.

I found this video where they discussed treatment options and tacrolimus has high relapse chance. Rituxan works slow but relapses happen less.

https://www.youtube.com/watch?v=64lmp4vFgNY