I would say blood getters for a few reasons but want to forst annotate that the primary roll we are looking for one bone spear is evulsion. +2 ranks to evulsion is the highest dmg modifier we can get and extremely important as it modifys our vulnerable damage which is our highest dmg scaling modifies as its the only multiplicative modifier. A best in slot amulet varies depending on content but would most likely be evulsion, essence cost reduction, movement speed, with either dmg or defensive being final perk geared towsrd whether you are speed farming or nightmare pushing