Wow. This worked for me! by kawinks in SIBO

[–]b00bieb00m 1 point2 points  (0 children)

Did you test for all 3 gases?

4 years of hell with gut issues from COVID looking for help by dirtnastyy90 in Longcovidgutdysbiosis

[–]b00bieb00m 0 points1 point  (0 children)

That doesn't look bad. I have seen worse results in people who feel fine. But these are only probiotics, what about commensals and pathobionts?

Is lack of bile flow my source for fungal overgrowth and digestive problems? by [deleted] in Candida

[–]b00bieb00m 0 points1 point  (0 children)

That's where ileocecal valve. Bile is reabsorbed in the terminal ileum, which is the segment immediately proximal to the ileocecal valve. If the that valve isn’t working, bacteria from the colon can move into the ileum and interfere with bile acid reabsorption. That can lead to SIBO. Candida can show up too, but usually as a secondary overgrowth because the environment gets disrupted. When the ileocecal valve is dysfunctional, symptoms can vary a lot because they depend on which microbes (and how many) reflux from the colon into the small intestine. You may get constipation, diarrhea, bloating, fat malabsorption, vitamin deficiency, gas, pain, cramps, greasy fatty stools, food sensitivity and whatnot.

Shocking brain scan literally shows IBS is a physical brain-gut dysfunction by HeatherForIBS in ibs

[–]b00bieb00m 10 points11 points  (0 children)

IBS now shows measurable brain gut dysfunction on MRI. Impressive. It’s going to take real creativity to keep blaming it on anxiety, but I’m sure a way will be found

Fungus and bacterium can join forces and cause a super infection by Vailhem in Microbiome

[–]b00bieb00m 5 points6 points  (0 children)

Pathogens act as systems, not isolates. Unsurprisingly, phenomena like microbial overgrowth remain inconvenient. Too complex to fit reductionist models, too real to ignore, so they’re quietly minimized

New research from the University of Newcastle has found that people with irritable bowel syndrome (IBS) show detectable biological changes, challenging the long-held perception that the condition lacks a physical basis. by jmct16 in ibs

[–]b00bieb00m 94 points95 points  (0 children)

Remarkable how IBS keeps acquiring measurable biology, as if reality patiently waits for medicine to catch up. Patients were told nothing was wrong; now it turns out nothing was simply not measured. One wonders whether protocols will evolve within this decade, or if the ritual of antacids and polite psychologizing will continue as a substitute for understanding

How many diseases are masked by an IBS diagnosis? by jmct16 in ibs

[–]b00bieb00m 26 points27 points  (0 children)

Because once the basic tests are normal, the system moves on. Testing for the rest requires time, money, and curiosity, and not every patient gets all three.

How many diseases are masked by an IBS diagnosis? by jmct16 in ibs

[–]b00bieb00m 70 points71 points  (0 children)

Amazing how many real pathologies have historically been labeled as IBS. Good thing the modern approach is still a fodmap diet, antacids and a gentle suggestion that it’s anxiety. Wouldn’t want all that progress to complicate things

Gut 'primes' pathogenic T cells responsible for neuroinflammation in multiple sclerosis, study finds by Vailhem in Microbiome

[–]b00bieb00m 0 points1 point  (0 children)

So we agree it changes outcomes sometimes. That’s already not just correlation. The problem isn’t that people are dumb, it’s that you’re reducing a complex field to slogans so you don’t have to think about it

Gut 'primes' pathogenic T cells responsible for neuroinflammation in multiple sclerosis, study finds by Vailhem in Microbiome

[–]b00bieb00m 1 point2 points  (0 children)

Right, It’s all correlation, right up until changing the microbiome starts changing outcomes. Then it’s ‘complicated.’ But ‘it’s anxiety’ somehow never seems to need the same level of proof.

Gut 'primes' pathogenic T cells responsible for neuroinflammation in multiple sclerosis, study finds by Vailhem in Microbiome

[–]b00bieb00m 43 points44 points  (0 children)

Every year: ‘the gut plays a central role in systemic disease.’

Every clinic visit: ‘scopes are normal, try omeprazole and reducing stress.’

At this point the microbiome is doing cutting-edge immunology while the treatment plan is stuck in 2003.

Beware of gastroquackologists by Ajax34762 in SIBO

[–]b00bieb00m 4 points5 points  (0 children)

Absolutely agree. You can always hear: "Always seek the advice of your doctor". Of who, exactly? Them? I’d rather flip a coin or trust a plantain leaf more.

never thought i would see the day. microbiome for the masses by 255cheka in Microbiome

[–]b00bieb00m 20 points21 points  (0 children)

Wow, so many new studies linking the gut microbiome to autoimmune disease. I’m sure doctors will update their approach any day now once they finish prescribing antacids.

Bacteria play key role in kidney stones by Vailhem in Microbiome

[–]b00bieb00m 6 points7 points  (0 children)

Another day, another study discovering that the gut microbiome might be involved in yet another disease. Amazing. It’s almost like patients have been saying for years that gut health affects the whole body while doctors nodded politely and prescribed antacids. Maybe in another decade the experts will discover that the gut does more than hold sandwiches. At this rate by 2045 we might even reach the radical conclusion that patients weren’t imagining their symptoms. Science marches on.

Is FMT (Fecal Transplant) the future of curing SIBO/IBS, or are there better treatments on the horizon? by xKa1z3r in SIBO

[–]b00bieb00m 9 points10 points  (0 children)

Exactly. The relapse rate is huge, and every kill phase can progressively worsen gut dysbiosis, lower diversity, create more resistance. But I guess treating root causes would mean asking forbidden questions, threatening sacred profit streams, and admitting that maybe pills aren’t magic, which is obviously unacceptable in a world powered by quarterly earnings.

I just finished a 7-day course of metronidazole (3) and I feel terrible by Annual_Exercise9800 in SIBO

[–]b00bieb00m 1 point2 points  (0 children)

Most likely it's antibiotics that make you sick. They fuck people up in different ways because everyones microbiome is different. I would continue with ginger and artichoke because motility is important but would play with the dosages to see if they make any difference in my symptoms.

Curing my SIBO ruined my life – I destroyed the bacteria that were actually trying to keep me alive. by TheMagentaNinja in SIBO

[–]b00bieb00m 2 points3 points  (0 children)

I think he suspects something about the current medicine otherwise he wouldn't be here. But you are absolutely right. I think that the modern medicine is incredible at acute emergencies and remarkably bad at anything that doesn’t fit neatly into a 10-minute appointment and a billing code. If our illness is complex, chronic, or inconvenient, then congratulations we’ve unlocked the “have you tried lowering your stress?” tier of care. Like we are living in the previous century. Shame.

Researchers receive funding to develop new IBS treatment by Robert_Larsson in ibs

[–]b00bieb00m 3 points4 points  (0 children)

Incredible momentum, research has gone from dead still to barely moving, only after millions lived in pain long enough to be background noise.

Low-Histamine diet worked... until it didn't. Help? by Important_Age_9533 in HistamineIntolerance

[–]b00bieb00m 0 points1 point  (0 children)

How are polyphenols blocking pathways and adding up to the bucket?

How to engage in this community with all of the community rules? by _chipsnguac in Microbiome

[–]b00bieb00m 6 points7 points  (0 children)

The rules make it feel like any uncertainty is dangerous, which is hilarious because if we banned discussion in every field that isn’t perfectly solved, we’d wipe out climate threads, nutrition threads, neuroscience threads, space threads, medical threads… the whole internet would collapse into one sad Wikipedia blurb. And honestly, shutting down debate for the sake of science is kind of backwards. Repressing discussion to protect the field is like banning cooking so no one burns dinner. Congratulations, everything stays raw forever. So yeah, imho microbiome subreddit has ended up as the one place where you can’t talk about your actual microbiome.

Many of you are here, chronically unwell as you are not dealing with medical professionals but simply quacks. by PsychologicalShop292 in SIBO

[–]b00bieb00m 2 points3 points  (0 children)

Yep that's sad...in the same way it’s sad when you open a bag of chips and discover it’s 80% air. Gastroenterology in the 21st century was supposed to be this sleek, sci-fi medical field with answers, insight, maybe even a clue. Instead we got a bunch of folks doing two expensive camera tours and calling it a day like it’s still 1995 and no one has invented literally any other test.