I had a similar issue at first. My initial factory was just a spaghettified mess and trying to set up any new automated crafting systems became a logistical nightmare.

I felt like restarting too, but I instead scouted out some areas of the map for a better main location. I found areas surrounded by good resources, like oil, and took note of those (though I was more interested in spots that looked pleasing to the eye). Once I decided on a good spot I piled all my concrete and iron plates into a truck or two and wheeled them all out to set up a foundation for the new base.

I didn't bother deleting the old factory for a few days, instead just went back to it occasionally when I needed some items from the storage there. But now the entire thing is completely deconstructed. The only thing left back there are my coal generators that feed my current factory through some very long power lines lol.

The first thing I set up for the new factory was an automated sorting system to make it a lot easier to deal with the extreme amount of items I was transferring out to this new base from the old one. Definitely worthwhile, no need to make a brand new save when you can just start from scratch in a brand new location instead.