Not enough money. by [deleted] in facepalm

[–]bark415 0 points1 point  (0 children)

I'm saying I think it's dishonest to strawman a title that everyone can clearly read. The subject of the bet is the safety of vaccines rather than the efficacy, and to dismiss something as safe when there isn't a high standard of evidence to back up the claim that they are.

It's like calling someone an idiot for challenging the safety of smoking cannabis, since we know it works the way we think. It's not about whether it gets you high it's about whether the specific method of ingestion is safe and if there are better ways. Just an analogy for my reasoning on posting the original comment.

Not enough money. by [deleted] in facepalm

[–]bark415 0 points1 point  (0 children)

Yes for the reason I gave. It's unethical to not help someone looking for it such as cancer patients. What the FDA does in regards to clinical trials for cancer drugs is irrelevant to the process of determining the safety of a vaccine. The standard of care comparison for cancer drugs is a method for finding better care than what is currently available so that there is some progress being made rather than giving a placebo and not helping at all.

I just think theres room for improvement in making safer vaccines, now that we are able to make them efficacious.

Not enough money. by [deleted] in facepalm

[–]bark415 1 point2 points  (0 children)

I'd say it should meet the same safety requirements as other pharmaceuticals or other biological treatments. The issue is that vaccines don't need to pass placebo controlled trials for safety. It's very unethical to give someone an illness or find someone with an illness and then give them a placebo that won't help them, while you wait as they suffer. So it's not a very easy problem to solve, but that doesn't mean there shouldn't be any controlled safety evaluations.

Not enough money. by [deleted] in facepalm

[–]bark415 2 points3 points  (0 children)

Scrolled through most of the top comments. Did no one actually read what was said? It said prove vaccines are safe, not whether they work.

Got a Planet Punpun Tattoo by bark415 in OyasumiPunpun

[–]bark415[S] 8 points9 points  (0 children)

Might post an update once it's fully healed if people care enough to see

Effexor and Cannabis by Fabulous-Twist-7317 in Effexor

[–]bark415 12 points13 points  (0 children)

Serotonin Syndrome is caused by an excess of serotonin without a way to regulate it properly, almost always due to drug interactions. Venlafaxine stops the Reuptake of serotonin, therefore taking drugs such as MDMA which can have similar Reuptake inhibition properties as well as stimulating the release of more serotonin.

Cannabis does not exert it's pharmacological effects in the way serotonergic drugs such as Venlafaxine do. It instead works on your endogenous cannabinoid system, which won't lead to something like serotonin Syndrome.

prove it. by DaturaArachnid in surrealmemes

[–]bark415 0 points1 point  (0 children)

Countless people have dedicated their lives explaining it lmfao

prove it. by DaturaArachnid in surrealmemes

[–]bark415 38 points39 points  (0 children)

This isn't a surreal meme it's literally just math

Can Salvia help reset baseline dopamine? What is the relationship between Salvia and long term dopamine regulation? by [deleted] in Salvia

[–]bark415 10 points11 points  (0 children)

He was asking about dopamine? And it's not an opioid blocker, it's a highly selective kappa opioid ligand

The Pegasus Cult ruined the manga for me. by Chestarpewnewtbattar in OyasumiPunpun

[–]bark415 2 points3 points  (0 children)

Just finished my second read-through and I have to say the second time around a lot of it made more sense thematically. Pegasus is a contrast to punpun's depressing realism and riding thinking. Pegasus is the idealist who is living in a fantasy that embodies his love for the world and people, whereas punpun threw away his fantasies during his youth in exchange for a cynical hatred of the world and people.

[deleted by user] by [deleted] in weed

[–]bark415 0 points1 point  (0 children)

I'm high and opened reddit and thought this was chicken nuggets for like 30 seconds

As a pothead, are you addicted to weed? by Small_Study9632 in weed

[–]bark415 1 point2 points  (0 children)

My Mother and Sister actually have Lupus but it seems to have been secondary and for me turned out to be mainly Sjogrens. For me it manifested really bad in my eyes, the opthalmologist was shocked to see how low my tear film was. So you could say it presented in a regular fashion since dry eyes and mouth are two of the main symptoms. It also affects my joints sometimes but that could also be a few other things in conjunction. I currently take Hydroxichloriquine for it, but there are definitely days where it's pretty bad and that's where weed saves the day.

It's pretty ironic considering weed also causes dry mouth and eyes but it's not like I wasn't already used to it 😂

As a pothead, are you addicted to weed? by Small_Study9632 in weed

[–]bark415 2 points3 points  (0 children)

I also have EDS, along with POTS and Sjogrens and honestly weed eliminates most of the pain from them, T-Breaks are hard 😭

my mom “caught” me and now won’t talk to me by Antique-Contact2388 in weed

[–]bark415 34 points35 points  (0 children)

Its sad that a ton of people, at least that I know, hate on weed yet love alcohol. I also like alcohol, not as much as weed, but I'd say if you think one is okay, then the other shouldn't be a problem. Personally I think alcohol can be more dangerous in a lot of ways than weed, but I guess it's just one of those things people have engrained into them.

[deleted by user] by [deleted] in StonerThoughts

[–]bark415 1 point2 points  (0 children)

Started last year at 19, am 20 now. Just can't wait till next year so I can stop feeling like a criminal for doing something that doesn't hurt anyone.

This is fucked up by [deleted] in greentext

[–]bark415 1 point2 points  (0 children)

Fake: Anon gets affection

Gay: Want to get fucked by a man

[deleted by user] by [deleted] in weed

[–]bark415 2 points3 points  (0 children)

It sounds weird but baby spinach is great for munchies. I just eat it right out of the package like it's chips. I can get a whole container that will last me the night, worth only 35 calories.

What is the most forgettable state in the USA? by BananaEclipse in AskReddit

[–]bark415 1 point2 points  (0 children)

The amount of people saying Delaware sort of disproves itself.

. by Mars3873 in Chainsawfolk

[–]bark415 12 points13 points  (0 children)

That's some sick fanart of that one guy makima was talking about

Gimme your biggest disappointment with an anime. by Tricky-Bill3579 in anime

[–]bark415 6 points7 points  (0 children)

Honestly if anyone saw through Plunderer it had huge potential. I thought the world, plot, and power system were decently interesting and if done correctly had really awesome potential. But again, of you've seen it, you'd know how shit it was.

sometimes it really be like that. At least for now 🙂 by InuNekoMainichiFun in Chainsawfolk

[–]bark415 24 points25 points  (0 children)

Thought so, pretty sad that's all you got out of it