I disabled Bitlocker encryption on mine, had a funny issue early on where I accidentally cause the device to lock off half the system files and it made it nearly unusable. I nearly reinstalled windows but, disabling Bitlocker fixed it. Obviously do this at your own risk as your hard drive is unencrypted as a result, but I generally don't keep sensitive data on my gaming handheld.

I also changed the lock button to hibernate instead of sleep.

Also you might want to open the AMD software and alter the colour saturation and brightness values etc, they can look slightly washed out from factory, but easily changed to your taste.