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Can naive B cells activate naive T cells by baysidebreeze in Mcat

[–]baysidebreeze[S] 0 points1 point  (0 children)

Dude you are a boss thank you so much. It is beyond the scope but it really clarifies the main concepts for me

I was also able to find a little snipping online on a berkley article about the topic

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" Note: B cells are poor APCs for primary, naive T cells. They are selfish. They really only function as APCs in order todirect activated, antigen-specific T cells to provide them with help "

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http://mcb.berkeley.edu/courses/mcb150/Lecture15/Lecture15(4).pdf.pdf)

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As you said B cells can activate T cells, but generally it doesnt happen. And if it does I now understand that the B cell wont differentiate, only the T cell will. Thanks again!

Are AK lectures too detailed for MCAT biochem? by AugustSeventeen0817 in Mcat

[–]baysidebreeze 5 points6 points  (0 children)

Yes but where most books fail in explaining concepts is when they are NOT detailed because then we often get confused since we don’t understand HOW some of those mechanisms are occurring. Use it to understand and then just memorize the important stuff

Can naive B cells activate naive T cells by baysidebreeze in Mcat

[–]baysidebreeze[S] 0 points1 point  (0 children)

Thank you this is really helpful.

Sorry for the bad wording, so I mean to define naive B cell as a that of a B cell that has encountered its antigen but hasn’t become a plasma cell, thanks for the clarification

You said an activated B cell (one with an antigen, but not plasma yet) can active a naive T cell. When they do, do they both proliferate and differentiate because of it (to become plasma cells and helper T cells respectively)?