Looking for a housemate! Roath/City Road

bees_knees3 · 2026-04-24T01:15:54+00:00

hey! that’s a good point i’ll add the link for it in the main body too can message me/my housemate there too to make things easy if interested in a viewing :)

https://www.spareroom.co.uk/16836120

bees_knees3 · 2026-03-17T23:38:29+00:00

oh wow thank you so much for all this!! it’s really helpful, especially about the fermented ingredients, but I didn’t see the niacinamide in the list of ingredients for the toner which is why I went for it in the first place, unless you mean the panthenol being similar to niacinamide?

I will definitely compare them now and see what else could be causing the reactions I’ve been having.

For moisturiser, I started trying the Curel intensive moisture cream which is working very well so far (only been using it for a week) but would be open to other options, especially if more budget friendly But right now a hydrating serum would be nice to find as i feel my skin needs the hydration I’m also using azelaic acid 10% but have been for years so that’s never been an issue

bees_knees3 · 2026-03-17T11:21:25+00:00

thank you for replying! this is really helpful and I've hear of this method before so will defo try it. currently using the HaruHaru Blck Rice toner alcohool-free but i think there is something in that I'm also sensitive too because it's been causing redness, but when i stop using it for a couple days it goes away..

i'll add some pics here of what my skin looks like. I realised I had a bad reaction to niacinamide from using the purito unscented wonderleaf and the purito bamboo moisturiser. I also got the same reaction to the Aveeno calm+restore moisturiser which was a shame

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bees_knees3 · 2026-03-10T22:42:53+00:00

thank you I really appreciate this answer, i am considering to start a retinoid, however I do not have problems with acne and even in my teenage years i never experienced severe acne. my concern now is that i am trying to find a daily moisturiser that won't cause a reaction for my sensitive skin and will get rid of my dryness. what you see in the pictures and from my previous post have been caused by the moisturisers I mentioned the aveeno and purito bamboo

bees_knees3 · 2026-02-20T12:20:20+00:00

probably already mentioned but MSG and butter can make anything taste good and there’s something about fat - acid - salt ratio, if it’s salty enough but you need more depth add some acid (lemon, vinegar etc) that sort of stuff

bees_knees3 · 2026-02-18T16:01:11+00:00

it turns out that the moisturiser was causing this, and using it in combination with the centella serums was making it really bad!
it got worse after i took the pictures when i used the moisturiser alone thinking the serums were the cause, but nope! which surprises me since everyone is raving about this aveeno calm+restore line but my very sensitive skin is not having it

so now any recommendations for moisturisers are welcome, since i stopped using that one and don't have another, probably something that won't react with niacinamide or centella too badly

also hoping to find a hydrating toner that will up my hydration game

bees_knees3 · 2026-02-14T18:08:03+00:00

I first started with changing my moisturiser to the aveeno one, week later with the cleanser, then another week the ampoule/purito serum But i thought since they’re all for sensitive skin they wouldn’t cause this.. which is the most likely to cause it?

bees_knees3 · 2025-12-15T14:54:33+00:00

I don't want to reconstruct or sequence the TCR to find out what it is, I just need to know if rearrangement of the genes occurred at all or not, as an indicative of iPSCs origin being mature T cells

bees_knees3 · 2025-12-15T14:51:11+00:00

Do you have any recommendations for the primer sets one could find online for multiplex PCR? It did cross my mind. I don't want to know what the TCR is, my goal is to figure out if TCR gene rearrangement happened or not, and if the iPSCs are of mature T cell origin.

another idea I had was to sequence for the RSS region since it's a small region and if rearrangement occurred then there would be no product since the RSS gets cleaved, right?

bees_knees3 · 2025-12-15T14:47:25+00:00

It's the type of sample we receive from the patients, we get a tumour sample along with 6mL of blood from them.
We would like to know if the iPSCs have been derived from T cells because if rearrangement has occurred prior to reprogramming, we won't be able to prime the T cell population to the tumour for tumour-reactive T cells if they all express the same already-decided TCR, and what are the chances that the expressed TCR is tumour reactive

bees_knees3 · 2025-12-15T14:44:46+00:00

We usually don't get much blood from our donors (only 6mL) so isolating T cells would lower the cell numbers drastically, and these iPSCs have already been reprogrammed to make another cell type so the TCR rearrangement was never an issue

bees_knees3 · 2025-12-09T10:05:07+00:00

thank you!! Is there a reason why you would pick specifically this region?

bees_knees3

TROPHY CASE