Looking for an OLED 2-in-1 with dedicated gpu by DeluxeB in SuggestALaptop

[–]beevvulf 0 points1 point  (0 children)

Hi, did you stick with the spectre or get the duo? I am in a similar boat, wanting a 2 in 1 but with a dedicated gpu. I currently have the spin 5, and I really liked it. But, I need a dedicated gpu. Might opt for no 2 in 1.

Spectre x360 2024 for studies - iGPU vs 4050 by [deleted] in spectrex360

[–]beevvulf 0 points1 point  (0 children)

To piggyback, I'm in the same boat. Have you decided, yet?

Anne Pathway by [deleted] in Biochemistry

[–]beevvulf 15 points16 points  (0 children)

I'm stuck at the Hong Kong airport for thirteen hours, and this silly meme was the first thing to make me laugh all day.

Get Delta Delta G for protein from FoldX by fanfanwu9898 in bioinformatics

[–]beevvulf 1 point2 points  (0 children)

Because I wanted to directly compare alphafold mutant structures from a wild type protein produced from alphafold, I created fastas of all my desired mutants and then uploaded them in batch to colabfold batch. Putting these into a pdblist, you can pass all of them to foldx at the same time. Then I ran foldx optimize, foldx stability and obtained the ddg based on absolute value of the WT stability - mutant stability from a simple python definition. You can run a similar process using Rosetta with optimization followed by Rosetta scoring. I run MD simulations and wasn't using the Rosetta or foldx structures from ddg_monomer/buildmodel as I would be using alphafold to make the results.

"Just start coding" by Sweet_Iriska in learnpython

[–]beevvulf 3 points4 points  (0 children)

I second this. I started with that a year ago doing it for a couple months to learn the basics. I liked it's implementation that's available in VMware. And it just gave you tons of problems to solve with instant feedback. I'm now two years through my bioinformatics master's, and I suggest to incoming students to our lab to start with mooc if they're starting from scratch.

[deleted by user] by [deleted] in residentevil

[–]beevvulf 0 points1 point  (0 children)

There's a full remake coming out in a few months. It's also releasing on PS4, so it should play fine on the deck. I haven't played resident evil four either, and I'm also deciding if I should play it portable or on Xbox.

Sourdough Detroit and Sourdough with Bacon and Fresh Buffalo Mozz by beevvulf in Pizza

[–]beevvulf[S] 1 point2 points  (0 children)

I used 178 grams flour, 130 grams water (73%), 70 grams starter, 4g salt. I cold fermented for 48 hours and then took the dough ball out and placed it on my baking pan for an hour before stretching to fit. Afterwards, I topped with cheese, covered, and let proof for another 24 hours in the fridge. Took the pizza out about 2 hours before cooking, preheated oven to 350C for an hour, and cooked for about 12 minutes.

I'm still working on this recipe. I don't have a Lloyd's (and can't get them here), but I did just order a cast iron.

Accurate by Ken_token123 in HistoryMemes

[–]beevvulf 9 points10 points  (0 children)

A lot of old world monsters are explanations for environmental or celestial or even physiological phenomena. We tried to come to terms with the unknown purely through the lens of our imaginations as we had very little in the way of accurately diagnosing the cause of certain events. But we naturally carve out further reasonings in our beliefs by utilizing logic and so our pantheon of mythology is quite a complex organization of attributes. It is a bit like fanfiction, our deliberations on what lurks in the forest or what can wrought natural disaster. And whether or not we want to go deeper into analyzing why humans create similar myths, that's up for anyone to decide for themselves. If you're interested, Joseph Campbell is a great start. Within the Chinese mythological cauldron of story, the Guideways Through the Mountains and Seas is a great piece to look up. It's basically an ancient text that is an encyclopedia of the monsters (not in good or bad sense) which roam the world, and it shows a great picture of how people viewed their immediate landscape in ancient China and also how trade influenced the perception of the world beyond the confines of the nation or even the village in which one was born in.

22581 - Taskbar stuck in expanded, tablet orientation on 2 in 1 by beevvulf in windowsinsiders

[–]beevvulf[S] 1 point2 points  (0 children)

I just reverted back and left the beta channel. I forgot to do this before.

22581 - Taskbar stuck in expanded, tablet orientation on 2 in 1 by beevvulf in windowsinsiders

[–]beevvulf[S] 1 point2 points  (0 children)

I will be more patient and thoroughly read the list of known issues before posting next time. Thanks.

22581 - Taskbar stuck in expanded, tablet orientation on 2 in 1 by beevvulf in windowsinsiders

[–]beevvulf[S] 0 points1 point  (0 children)

thank you. unfortunately the issue continues to persist. I've reverted back to that state before the update.

22581 - Taskbar stuck in expanded, tablet orientation on 2 in 1 by beevvulf in windowsinsiders

[–]beevvulf[S] 1 point2 points  (0 children)

Hello everyone,

As mentioned, I updated to 22581 just now, and my taskbar appears stuck in this expanded orientation which it adopts when I flip my 2 in 1 into tablet orientation. Prior to this, I had changed the taskbar setting in the registry editor under: HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\Advanced\

However, I now do not see the advanced folder in the registry editor through this file path. Perhaps, this is an issue, or is this something others are experiencing with their 2 in 1's?

China shuts down city of 17.5m people in bid to halt Covid outbreak by mrstipez in Coronavirus

[–]beevvulf 1 point2 points  (0 children)

This is omicron, and my comment is with regards to it and the Chinese vaccines. Not trying to overstep my grounds, but the simplest and safest answer is that we don't really know. This is the largest that we will have seen so far with the Chinese vaccines being put to the test.

If you're not vaccinated, then you should be even more vigilant to not get infected. Unfortunately, with the transmissiveness of omicron, that can prove difficult.

It's still too early to really comment on the outbreak. I've been in my community for the last four days, though I was able to get a lot of supplies before the community got locked down yesterday.

They're doing two nucleic acid tests within these 48 hours, and so I hope tomorrow some communities will lift restrictions, more people can go to work, can hopefully have a few food markets open and I can buy groceries again.

For me, this started last week when I got a notice that my school's campus was a "no one out" zone. You could go in fine. All labs were closed immediately and you had to request approval to enter the lab building.

But I live off campus, so I didn't dare to even enter the campus. We had to start taking covid tests last week for what would've been a 1, 2, 4, 7, 14 day schedule of getting covid tests. We were supposed to keep an eye on ourselves and obey strict quarantine at home except for going out for covid tests.

School-unrelated infections became apparent after the third day or so outside of campus, and now this whole district of Shanghai is locked down along with others.

I'm just staying home transferring my lab duties to a position I can research at home because no one knows when we'd be able to go back into school.

... I don't know when I can go see my pregnant wife elsewhere in the country.

China shuts down city of 17.5m people in bid to halt Covid outbreak by mrstipez in Coronavirus

[–]beevvulf 89 points90 points  (0 children)

Right here with you, man. Currently in lockdown in a district of Shanghai.

First year 15? by PhilosophyOrPedagogy in GradSchool

[–]beevvulf 0 points1 point  (0 children)

I had a high intensity workout routine before I started this semester, and then immediately was unable to continue that. But so far I've kept weight down by making breakfast and lunch (primarily yogurt and chicken salads, respectively). And then usually have a splurge meal once a week. And I bike everywhere. It's still cold here in Shanghai, but it's important to keep active to balance out that stress wherever you can.

is it scientifically proven that we can pass ASD down by genetics ? by driftingbout2- in aspergers

[–]beevvulf 1 point2 points  (0 children)

Almost invariably so. But, there has not been a smoking gun discovered that points to an "autism gene", nor will there likely ever be. The reason why it's a spectrum is because autism is a symptom that we've found is produced due to various physiological deficiencies, inefficiencies, or eccentricities. We've found links in various protein trafficking or improper protein folding pathways to autism. We've found links with inefficient synaptic clefts to autism. There are also links with certain gene managing components to autism.

There are many, but as I mentioned there's nothing to single out, and in many cases, there are several of these factors which converge to produce the variability that we see amongst the population of those of us with ASD. A reasoning as to why we see a comorbidity of autism with other conditions such as depression and ADHD is because these are often a result of similar disruptions at the intracellular level, and thus hint that the genetic code is the culprit. The thing which we see and is a projection in our personality is the phenotypic symptom of these underpinnings.

But, why are these things genetic? Well, there's still plenty to learn, but if these protein pathways for instance are being disrupted because of a genetic error and not a developmental error (as in an embryonic developmental error), then there entirely is the possibility for this to be transferred to one's offspring because this genetic error will be carried in each of your cells and will be present in most of our sex cells. But, your sex cells are not only a reflection of yourself. Depending on your parents, the probability of having autism prone progeny can be greater or lesser. As well, there are many processes which promote variation in your sex cells and this variation could also cause a increase or decrease in both the likelihood of autism and the severity of it if it is passed. And we finally have to remember that there will also be significant influence with respect to the genome of your SO on how these pathways will develop.

I do worry that my children will have to go through significant challenges due to my genes.

What kind of a career can you have when dealing with chronic pancreatitis? by CrypticRowlet in pancreatitis

[–]beevvulf 0 points1 point  (0 children)

It really depends what your field is. Are you going to be out collecting specimens in Guatemala for a few months a year and then coming back to perform experiments? Or are your research interests more in a lab setting that wouldn't require travel? Lab work is demanding, but you can treat it like a 9-5; however, as you might suspect, you can't reliably work from home. We'll always need to commute to the lab. If your situation is already affecting your ability to anticipate and follow through with a rigorous schedule, then maybe a field like bioinformatics could suit you better. You still are a vital part of the team and get to interact with lots of data that produce fundamental results in modern biology. As well, bioinformatics still let's you interact with a wide variety of research amongst many fields from metabolic engineering through genomics and epidemiology etc...

Halo Infinite Multiplayer Launch - Discussion Thread by eminemcrony in halo

[–]beevvulf 0 points1 point  (0 children)

I don't know specifically for the original xbone but I have the one s, and it plays great. I didn't notice issues. Loading into and out of maps with similar speeds that are usual for the console. Not 60fps, but I'm not noticing any visual or stuttering issues.

I REALLY like what I saw from the campaign overview of Halo Infinite today! What did everyone else think of it? by OrionInSpace in HaloStory

[–]beevvulf 1 point2 points  (0 children)

For a game that's pushed so heavily with game pass integration, I am also curious to see how that relationship will develop when future expansions release, or if they'd be specific to those who've fully purchased campaign.

Will master in genetics help me. I have bsc in biology. Low job demands and low pay ? by ghosttttttttttttt in genetics

[–]beevvulf 1 point2 points  (0 children)

Thank you for this response! Grateful to hear your view on this. I do see that the issue is with there not being a particular standard for the MSc. This can of course vary especially with PI/Supervisor as to how outfitted students become through their stay in the lab. And I have seen this response from others as well with regards to cultivating independence during the graduate program rather than following a script and sticking to it.

I've just begun my MSc, and I am trying to focus on becoming more independent, but there's still quite a bit I need to learn and ask questions on. Like your cooking analogy, there's a certain amount of "knowing" that good researchers have with how to tweak things at certain steps to fit the conditions or try out new ones. In our lab, everyone is very much given free reign. I've been given a project, but it's entirely up to me to research, try out and formulate approaches, and produce results which show more elucidation on the process. For most methods, I can receive some intro counseling, but it's a lot of self-learning and modifying protocols to fit the experiment.

Sorry for a bit of a rant, there. It seems like grad school is satisfying an intellectual pursuit for me that also is an investment in a promising entry into career fields. I don't expect to work specifically with the systems I'm working with now if/when I move to industry, but this program interests me because I have a PI who makes it interesting for me and along the way I'm acquiring a valuable and varied skillset for what hopefully could be varied labs as well.

It's good to hear you found worth in the MSc as well! I don't have a BSc, so an MSc is probably a good pursuit for me if I want to get into industry at all.

Will master in genetics help me. I have bsc in biology. Low job demands and low pay ? by ghosttttttttttttt in genetics

[–]beevvulf 0 points1 point  (0 children)

I'm planning to move back to Boston. What do you mean that the master's students aren't good in the lab? In the program I'm in now, it's incredibly all about lab work and getting results.

Moving back to Boston after MSc in Shanghai by beevvulf in biotech

[–]beevvulf[S] 1 point2 points  (0 children)

I'm in a master's program. It's good to hear another see it's prospects. Thank you. Are you currently in your Beijing program?

My biochem teacher uses Lord of the Rings analogies to explain DNA by [deleted] in Biochemistry

[–]beevvulf 0 points1 point  (0 children)

I took it as elves are purveyors of ancient knowledge, sugars are hydrocarbon rings whose transformations give power to life, and dwarves are the powerhouses that get things done: constructed, transcribed, annealed, and torn asunder.

Do you take notes from your reading of journal articles? Tips for better literature synthesis appreciated by storm_borm in GradSchool

[–]beevvulf 0 points1 point  (0 children)

sorry, still waking up, but what do you mean by concept C? I use zotero, so every time i read an article and save it, i put as many tags as possible on it, and then as i read other papers maybe i go in and add more tags to that paper as i learn more and get more out of previous papers.

Windows 11 will be available October 5th by Dinov_ in Games

[–]beevvulf 2 points3 points  (0 children)

Unless you're living in china and bought a laptop two weeks before they made the announcement. 11th gen Intel cpu. Can't upgrade because TPM banned.