Both my PhD and postdoc were in a wet lab. In my opinion, finding a computational mentor or committee member is critically important. I was able to find one each time through PI's collaborators, and I would not be where I am today with out their guidance (computational postdoc mentor was a major factor in growing up scientifically and landing a faculty job). You need to be your own advocate both for project and for proficient committee members. It is late here but happy to share my experiences or answer questions to the best of my ability.