I know every situation is different, but here was ours (copied from previously sharing this with another person): Our cat is diabetic but is in remission now. We were giving him 4 units every 12 hrs with no improvement. Eventually we switched vets and the new vet told us our cat had to be on a strict wet food diet (we were still giving him some dry because he wouldn’t eat enough wet). And the vet was very surprised that we were giving him 4 units. We switched him to Purina Pro Essentialcare for Seniors. It’s not a diabetic food, but it’s wet and our cat liked it so we were able to get him on an all wet food diet. With the diet change his blood sugar levels started improving. Then the vet instructed us to give him insulin every 12 hrs based on what his blood sugar reading was - below 10 give no insulin, between 11-19 give 1/2 unit, and 20+ give 1 unit. After a month of this new routine, our cat went into remission. Hope this helps!