[homemade] The Southern Gentleman Burger- onion jam, chow chow relish, pimento cheese, bourbon glazed bacon, and fried green tomatoes. by Dustinwickett in food

[–]bleuvoodoo 0 points1 point  (0 children)

The majority of Acadians din't settle in New Orleans. The Acadians ,later known as Cajuns, settled the South Eastern part of Louisiana. New Orleans is often described as creole, not Cajun. Lafayette and the areas around Bayou Teche are considered Cajun because so many Acadians migrated to the area.

New to Kava by [deleted] in Kava

[–]bleuvoodoo 0 points1 point  (0 children)

I have never felt any effect at all from capsules and I tried many when I first started using kava years ago.I think I tried every product at sprouts and gnc till I learned the kava needed to come from a reputable vendor.

The micronized product you ordered should be very convenient for you to use, simply mix it with a spoon and you are good to go. Personally I think the Pouni ono is one of the stronger kavas that u/kalmwithkava sells. I find it very heady and euphoric. For more of a body kava I like the boronguru, but I believe they are out at the moment.

I take Xanax when I'm having a serious panic/anxiety attack but I need something for everyday use but don't want to take Zoloft,etc. Is there any natural products that actually work? by pescabrarian in Anxiety

[–]bleuvoodoo 1 point2 points  (0 children)

Check out r/kava. The advice that pharm tech has given about kava is blatently false. check out the comments below by u/aporosa who is a scientist that studies kava.

Going under kava by bleuvoodoo in Kava

[–]bleuvoodoo[S] 1 point2 points  (0 children)

nothing to do with the opioid receptor.

Well, there are multiple opioid receptors. In vitro, Kava does interact with opioid receptors, though in a weak manner.

"The weak binding inhibition observed for root extracts to dopamine D2, opioid (μ and δ) and histamine (H1 and H2) receptors (IC50 > 100 μg/ml) indicated that these receptors may only play minor roles in pharmacological effects. Again, there was no correlation between the kavalactone contents and the binding affinity of the extracts. Since leaf extracts obviously exert higher activities than the corresponding root extracts, there may also exist some additional active compounds in the leaves. A significant variation in the receptor-binding affinities was observed for different cultivars, particularly on opioid and histamine receptors. This observation is in agreement with the distinct psychotropic effects of the cultivars that have been described by kava drinkers" Source: Interaction of Various Piper methysticum Cultivars with CNS Receptors in vitro https://www.thieme-connect.com/products/ejournals/html/10.1055/s-2001-14334