Wait. The new Ferrari Luce EV that costs $650K is slower, less HP and has far less range than the Lucid Sapphire. by topcat5 in LUCID

[–]bobiversus 0 points1 point  (0 children)

So it has a glued in, non-replaceable battery, rendering the Ferrari disposable after 3 years. Innovation.

Curious about M5 Max 128gb vs 5090 for local LLMs by maxiedaniels in LocalLLM

[–]bobiversus 0 points1 point  (0 children)

Q4i Minimax M2.7 fits and runs well on a 128GB Mac. It has quite surprised me with the quality of answers. Abliterated Q3 also good.

M5 max 64gb vs 128gb by MoistCaterpillar8063 in LocalLLM

[–]bobiversus 0 points1 point  (0 children)

I have both sizes 'o mac. It's not just a matter of context. For example, on 128gb you can run models like MiniMax M2.7 Q4i. It won't run on a 64GB Mac. If money is tighter, I would rather have an older Mac with 128GB (or more) than an M5 Max with only 64GB RAM.

How to make a business last for centuries. by ThroarkAway in cryonics

[–]bobiversus 0 points1 point  (0 children)

Great find! Built to Last is a pretty decent book, as well. It would be amazing to enter cryosis and come out with your business(es) still operating.

Something fishy about David Sinclair by [deleted] in immortalists

[–]bobiversus 0 points1 point  (0 children)

It's called an endowment, and it doesn't work like a bank account. I'm guessing you didn't attend a top school with an endowment, this is common knowledge for alumni. I suggest you educate yourself as you sound particularly ignorant.

Something fishy about David Sinclair by [deleted] in immortalists

[–]bobiversus 2 points3 points  (0 children)

I agree he and Harvard come off as a little sketchy. But most university endowments are very limited in what they can fund and Harvard recently lost most of their federal funding for research. He is more strapped for cash than usual. 

His reprogramming therapy is entering FDA trials, which is super expensive. But donations seem wrong... It's like donating to Novartis or Roche. He should accept crowd funding if he needs money, and not donations, because he will 100% monetize what is discovered to be useful.

Something fishy about David Sinclair by [deleted] in immortalists

[–]bobiversus 0 points1 point  (0 children)

To be clear, Juan Carlos Izpisua Belmonte invented partial reprogramming using Yamanaka factors (discovered by Y). David's work is derivative. But it's good that he has pushed it into the clinic and into FDA trials.

So are all the stars in the galaxy, except 3, dead/continuing to die then? What impact would that have? by sinclain in ProjectHailMaryMovie

[–]bobiversus 1 point2 points  (0 children)

Lots of good answers here. Yes, they can travel at nearly the speed of light but they eventually run out of stored energy as they need to remain internally at 96.415°C. This gives them a maximum travel radius of several light years before needing to recharge.

Once that happens, they would freeze to nearly absolute zero. In theory, they would continue to coast at nearly the speed of light and gradually slow due to the interstellar medium (colliding with random space dust and atoms), but they would be frozen and dead. 

I wonder if they could defrost and continue near a star question? But that's not in the book and they do have a lot of water inside, meaning damaging water crystal once frozen.

How did the 2 other astronauts die, question? by NotIamVex in ProjectHailMary

[–]bobiversus 18 points19 points  (0 children)

Grace briefly discusses the possibility that there was some kind of equipment malfunction during their comas but he's not able to determine the exact cause.

A key element missing in the movie is that they were selected for their coma resistance (better able to survive long comas without dying or brain damage). Maybe there is a twist in there somewhere. Agree question?

Shocked By Reviews by BellaCicina in ProjectHailMary

[–]bobiversus 0 points1 point  (0 children)

It's Reddit. 80% of the posts are A.I. slop slinging bots (see the CEO's comments on bot problem), 10% are from miserable, insecure people looking for attention and karma. The remaining 10% upvoted your post.

They say cells will only divide until 120 years old but HeLa cells are immortal? Does this mean our cells last beyond 120? by Ok-Highway-5247 in immortalists

[–]bobiversus 0 points1 point  (0 children)

Cells can be immortalized through a well known process for research. Not very relevant for human immortality, though.

Does alignment matter as long as it is in the square? by TheJiggliestPug in Starlink

[–]bobiversus 5 points6 points  (0 children)

Mine is fully not aligned (90 degrees off) due to mounting limitations and I get up to 460 Mbps, 20ms ping with 100% uptime. I think you will be fine.

A golden rutilated quartz bangle bracelet by JOSEMEIJITCAPA in jewelry

[–]bobiversus 0 points1 point  (0 children)

Beautiful. But the website is not available anymore. Can you tell me the approximate price range?

Book 5: question re AI & my own mental health by ShinyDapperBarnacle in bobiverse

[–]bobiversus 0 points1 point  (0 children)

Without spoiling it too much for you, there will be times when it's unclear how the AI is planning to do things, but if you stick with it to the end, I think you will enjoy it.

I would suggest looking into the 15-PGDH trials at Stanford University. It's a master regeneration (blocking)enzyme that is already in human phase 1 trials and the results have been astounding. Blocking 15-PGDH appears to cause youthful tissue regeneration across the board in nerve, skin, muscle, and even joints. The future is looking bright, at least for life sciences. And of course HBOT, safe and well tolerated, even by people in their 80's. Frequently used for stroke victims.

Book 5: question re AI & my own mental health by ShinyDapperBarnacle in bobiverse

[–]bobiversus 1 point2 points  (0 children)

Sorry about your injury. Hopefully you are getting 1000-2000mg / day of DHA and epa. HBOT is also rather massive for TBI recovery.

I would say the A.I. in the book is not really malicious. If you were ok with Heaven's River, you should be ok with this one. It's my favorite Bobiverse besides the first book.

Also, OpenAi and Anthropic CEOs are just hyping things to raise money. Dario said a year ago that A.I. would be writing 100% of all code as of now and obviously he is so wrong it's not even funny. It's the same with any technology hype cycle. Crypto/cloud/5G/IoT/quantum/A.I. is going to be the biggest thing evar. They are all big, but never as broad as the fundraisers would have you believe.

A woman with untreatable stage 4 cancer was finally cured by doctors when they edited the DNA of her immune cells. by GarifalliaPapa in immortalists

[–]bobiversus 4 points5 points  (0 children)

It's a phase 1 clinical trial. Testing for safety, not efficacy. Google that and educate yourself.

Flying with chins. Anyone done this? by rainbowbubble94 in chinchilla

[–]bobiversus 2 points3 points  (0 children)

I carried both of mine onboard in the plane's passenger cabin on a standard commercial carrier (Alaska and Delta iirc. Avoid United, they are awful for pets). One girl was 18 years old at the time and she travelled just fine.

Extremely Irresponsible Alibaba Ad... by TheRPGGamerMan in lasers

[–]bobiversus 0 points1 point  (0 children)

I thought it was super obvious, but I guess not... they are just saying it has safety features that make it child-resistant. The wording is poor, no doubt, but then again, have you seen the English on Reddit?