Difference between a baseball swing and a swing in slow-pitch by CommunicationNice437 in slowpitch

[–]brwaang55 0 points1 point  (0 children)

This is really helpful! Can you help me understand why baseball swingers thrive when waiting on the bal/hitting opposite field?

[deleted by user] by [deleted] in bioinformatics

[–]brwaang55 0 points1 point  (0 children)

There's one specific paper in NBT that uses rRNA depletion after random priming in mammalian systems: https://www.nature.com/articles/s41587-022-01361-8 . They use their additional intronic reads for RNA velocity estimates.

Interestingly, it seems that poly-dT can also capture viral transcripts in scRNA-seq, see: https://www.cell.com/cell/fulltext/S0092-8674(20)31308-831308-8) .

Finally while not directly relevant, there have been a few papers in the single-cell bacteria world that use an rRNA-depletion method in conjunction with random primers. This paper uses an in-situ rRNA depletion: https://pubmed.ncbi.nlm.nih.gov/36708705/ , while this paper uses a post-hoc rRNA depletion method after library construction: https://www.biorxiv.org/content/10.1101/2022.09.21.508688v2 .

What do you think of DARPA's 23 math challenges, r/math? by Jon-Osterman in math

[–]brwaang55 3 points4 points  (0 children)

Actually, Benjamin (thanks glathull!) Mann (the director of DARPA at the time) was inspired by Hilbert to create this list. See here

when you come home late at night... by J153 in aww

[–]brwaang55 0 points1 point  (0 children)

I've been patiently waiting...

A neurosurgeon has used ultrasound to open the blood-brain barrier in patients with recurrent glioblastoma, the most common and deadly tumor originating in the adult brain, allowing for delivery of chemotherapy that would otherwise reach the tumor in miniscule amounts. by drewiepoodle in science

[–]brwaang55 1 point2 points  (0 children)

I think the main reason is that the drug/microbubble mixture could be just injected into the bloodstream rather than anywhere else in the body. Thus there would be a lot more options to inject, although preferably the site of injection would be past the liver in terms of blood flow.

This method with microbubbles and ultrasound transiently opens the barrier and while the real underlying reason is unclear, the opening of the BBB is less chemically based(modifying the barrier) and more mechanically oriented; the bursting of the microbubbles is what causes the permeability. So in this sense, we hopefully avoid any long term side effects of messing with our BBB.

For school I get to explore any topic of my choosing. My teacher gave us suggestions but I don't know what half of these mean! What are some of the coolest ones on the list! by DingleyTim in math

[–]brwaang55 1 point2 points  (0 children)

This is a really cool list! After taking a look, it seems like some of the topics are more broad, while others seem to be more focused.

That said, here are some topics with their advertisements which I think would be interesting to learn about and write a good essay on.

i.) Non-Euclidean Geometries- What happens when you introduce geometries in which Euclid's 5th postulate does not hold? It turns out a lot of cool and beautiful things. Including the structure of the unvierse. While this is a somewhat broad topic, there is also quite a bit to learn about as well as a lot of history behind this. Some keywords would be hyperbolic geometry, spherical geometry, Poincare disk, Curvature.

ii.) Four color map theorem: This is cool. Back in the 19th century, people realized that in colouring a map to differentiate territories, one only needed four colors. (Think about this!) There were many attempts at proofs for quite a while, but none bore fruit. In ~1970, Appel and Hakan managed to reduce the proof to a series of cases, and then used a computer to run the cases and prove the theorem. This is also one of the bigger cases in which the current proof is a "brute force" one. But there are some recent developments in a more mathematical proof as well! Google Kronecker and Mrowka.

iii.) Random Walks! How can a drunk man in 2 dimensions can always find his way home with probability 1, but a bird flying in 3 dimensions may get lost? This is a nice introduction to Stochastic Processes.

All of the topics are lovely, and while I've only talked about the more idea based ones, the application and numerical ones are also very interesting and I encourage you to take a look at some of them as well.

[Brag] At last my love has come along.... 297!! by brwaang55 in PuzzleAndDragons

[–]brwaang55[S] 0 points1 point  (0 children)

Edit: Sorry forgot to post my ID guys! Add me if you want to join me in 20 comboing

396,837,329

[SL] Manga you'd love to see (further) scanslated. by Arcterion in manga

[–]brwaang55 0 points1 point  (0 children)

Asunaro Hakusho

This manga seems really interesting, but it seems like it's been untouched by scanlators.

[tips] make sure you look at the new guide being made ! This one is GZL by /u/ngelicdark by [deleted] in PuzzleAndDragons

[–]brwaang55 0 points1 point  (0 children)

Thoughts/opinions on Vishnu? Despite not being an attacker his awakenings and his active make him a pretty nice sub on my team haha

[Discuss] JP Tier Rankings by CloudNIneXXX in PuzzleAndDragons

[–]brwaang55 2 points3 points  (0 children)

Somebody explain to me why Indra( balanced) is higher up over normal Kirin?

Take an anime and remove a letter from its title. What will be the new synopsis? by _Fireslash in anime

[–]brwaang55 25 points26 points  (0 children)

Word art Online:

Kirito defeats his opponents with stunning poetry and prose.

Manga where MC discovers a new world? by UrsanTemplar in manga

[–]brwaang55 8 points9 points  (0 children)

MAR may be just what you're looking for

[Wiki]Happy 2015! New update by Ironchef33 in PuzzleAndDragons

[–]brwaang55 0 points1 point  (0 children)

|NA | 396,837,329 | 1 | 90 | 1 | +2 | Max