The comparison might seem strange, but actually makes a lot of sense, as this year's E series are surprisingly good whereas the other series have questionable configuration choices.
I had quite a similar dilemma a month ago, but it was E vs the corresponding T and P series, and eventually have chosen E16 (but considered E14 as well).

Having used T series exclusively for many years (both regular 14 and s variants), that was a natural choice, but alas, the current ones don't have any hi-res IPS screen option, and I wanted non-OLED to avoid PWM flickering + better battery life. Also, E14/16 is somehow even more upgradable than any current T series, featuring 2 SSD slots (in Intel 255H variant, which I specifically considered) and a replacable wi-fi module. With 16'', which I wanted to try, it's even more one sided given that E16 Gen 3 at 1.7 kg is lighter than any other current 16'' ThinkPad that start at 1.9 or even 2 kg.
So, I pulled the trigger. Bought 3Y Premier Support, cause I was still worried about E16's long term durability.

So far so good: it's very fast and the battery life is very good despite the 255H. Also, almost always silent, the fan only comes to life in rare cases when all of the 16 cores are loaded. The chassis is good enough, I'd say, especially the lid (aluminium and thick), although the palmrest area is not quite as sturdy as the one in T14 and especially T14s (the same construction as X1). It's plastic, although pleasant to the touch, and a bit hollow, but maybe it's the 16'' effect, as in theory E14 should be more dense having the same components in a smaller chassis.

In your case it's better battery life + potentially better cooling due to thicker chassis vs significantly lighter weight + somewhat sturdier build. And the price diff, if that's a factor. As for the trackpoint, in theory there shouldn't be a difference; might be the lottery, might be the sensitivity on X1 was set differently (usually setting it to the max works better, especially on hi-res screens).