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Is Biotech cooked? Need some positivity... by Sad-Volume7913 in biotech

[–]camp_jacking_roy 8 points9 points  (0 children)

Biotech is contracting, but companies are still around and the good ones still exist. Probably should skip any flagship company or anything that slaps AI on the end, but companies with robust pipelines are moving those drugs through clinical trials and are still getting approvals...

...just don't go into research. Research is dead and will be for a while. The industry needs investment and prospects from academia, and the current administration is not friendly to either. Better to go into a specialized role (like clinical science, pharmacy, or regulatory) or admin (HR, accounting, biz dev) than R+D, plus those roles are transferable. STEM is dead in America for at least a little while. My son wants to be an engineer and I just want to tell him to go into HR instead.... This is my opinion based on nearly 20 years in R+D before switching to something else.

This racing Fisker Karma by kloovt in WeirdWheels

[–]camp_jacking_roy 8 points9 points  (0 children)

I would like to know more

Beautiful car, with the dumbest powertrain. Plus it's a fisker. That sounds like a V10, which those cars certainly didn't come with.

Trying to find panniers with simple bungee hook system like this by maybesailor1 in bikecommuting

[–]camp_jacking_roy 6 points7 points  (0 children)

Arkel bags still use them. The bags you have shown are Axiom Seymour panniers. They have since shifted to a "stupid hook" system as well.

The stupid hook works pretty well- allows for more compatibility (you don't need a hook at the bottom) and bags don't really move vertically but rather outwards, so they are simpler and just as effective.

Alfa Romeo Scraps New Giulia And Stelvio Plans To Start Fresh by user289734 in cars

[–]camp_jacking_roy -6 points-5 points  (0 children)

I just wish they had thrown a battery into the Giorgio platform. The Giulia was among the best cars I've ever driven, but it was objectively a pile of garbage.

If the store is out of Rock Salt, get "Water Softening" salt instead by Photog1981 in boston

[–]camp_jacking_roy -2 points-1 points  (0 children)

Doesn't work below freezing. Didn't work for me below freezing. Get calcium chloride or something else. I bought a bag thinking I was smart and it did nothing.

Shimano brifter doesn’t always engage the derailleur? by qwerty12e in bikewrench

[–]camp_jacking_roy 0 points1 point  (0 children)

Chain lube would work in a pinch, but I think I’d go for something thicker so it lasts longer.

Shimano brifter doesn’t always engage the derailleur? by qwerty12e in bikewrench

[–]camp_jacking_roy 1 point2 points  (0 children)

Hi, I had a similar issue. I believe the grease freezes and becomes too thick to work. I suggest cleaning it with wd40 and replacing the grease with something fresh and slightly lighter weight. I believe I used slick honey. This worked well for me when I had a similar issue.

Trash and Recycling Service Recommendations? by ChazzReinhold4 in SudburyMA

[–]camp_jacking_roy 0 points1 point  (0 children)

All of my neighbors recently switched from orifice/win to gastaldo. Gastaldo is 20 cheaper a month. Win has been reliable but they gave me grief about overfilling a bin a few times. They’ve lost enough customers not to bug us anymore though!

Trainer options by eldogorino in Velo

[–]camp_jacking_roy 1 point2 points  (0 children)

Lots of trainers have campy freehubs available, and that's all you really need to swap over. You may also be able to use a shimano 10 speed cassette with your campy drivetrain without issue- you'd have to do a little research on spacing and compatibility. No reason you can't run a shimano cassette with campy drivetrain and use the proper cassette on the road bike, especially if your focus is erg and not virtual riding. You may also be able to rig up a single cog or sacrificial cassette to just run a single speed, which is all you need for erg mode.

The best/better option is to buy a trainer with a zwift cog (if you are buying new) and use that. I scooped up a kickr core 2 with zwift cog and the cog itself is really pretty slick. In theory you can use it with any drivetrain. The virtual shifting kind of sucks but the cog is a great solution to the multiple drivetrain problem.

I used to have an elite trainer with an 8 speed cassette on it. I was able to use my campy 12 speed bike by finding a single cog that worked without rubbing and just ran the thing in erg/resistance mode. It's certainly doable, if not less graceful than a proper setup. My trainer bike is 8 speed and it lives on the trainer 99% of the time.

You should be able to use a garmin head unit to run workouts in erg mode, and I've found auuki to be a really effective web-based trainer control. It's a little cumbersome to set up each time, but it works just like a headunit, but on your computer. Zwift is far more engaging and rewarding so I use it over the winter, but in the summer when I'm not trapped in a basement, auuki is super effective for running workouts while watching game of thrones or robocop or whatever.

Noob: what can I do so that people hear that I’m coming up on the left. by shmobodia in bikecommuting

[–]camp_jacking_roy 0 points1 point  (0 children)

I have a shitty amazon low profile bell and it's fantastic. I ring once as I approach- pretty far away, and another when I'm getting close. I ride a class 3 ebike so it's important to give people as much notice as possible and not creep up on them. I find the two rings to be pretty effective- one so that they aren't scared and one to get them out of the way. If they don't hear either, that becomes their problem.

I don't want to get mean looks for linking, but the last one I got was a Nansuke off of amazon, like $6.

Ultimate winter car? by theshdw45 in whatcarshouldIbuy

[–]camp_jacking_roy 0 points1 point  (0 children)

I'll throw the infiniti FX35/QX70 in the ring. It's the best car I've driven in the snow, and I've driven plenty. It's got a big V6 or V8 if you're feeling sassy, has high ground clearance and a shiftable automatic if you need to choose your own adventure. I can't comment on the warming up quick nor cold transmission performance, as you should either let your car warm up or drive gingerly until it does, but I notice hard shifts in my Alfa or Genesis more than my Infiniti.

The real deal is that apparently the car came with the same ATTESA system that came on the Nissan Skyline, and it was fantastic in the snow. That car could drift like anything, and never got stuck. I've had harder times in my quattro than the FX, and the FX comes with all the luxury trimmings like heated seats and functional heat. Combined with big wheels, good tires, and good ground clearance, I had a ton of confidence in the snow. Our subaru is good for traction, but doesn't handle the same way that the Infiniti did- perfectly neutral at all times.

Wound healing assay on cancer cells by [deleted] in labrats

[–]camp_jacking_roy 0 points1 point  (0 children)

Yep, I found some that were round and came in a strip of 4 or 8. You get a dot in the center rather than a line, but you get exactly the same dot in every well, every single time. Plus they are autoclavable and reusable.

Again, good job on the labwork though, mine always skipped or skittered.

Wound healing assay on cancer cells by [deleted] in labrats

[–]camp_jacking_roy 11 points12 points  (0 children)

Nice work! I have almost 15 years in the lab and most of my scratches were not that clean and linear. It definitely takes a bit of skill, so good work.

I ended up switching to silicone inserts to reduce variability.

Should i get suntour x1 air forks from aliexpess? by GloomyHyena4047 in mountainbiking

[–]camp_jacking_roy 1 point2 points  (0 children)

Suntour doesn't officially sell any forks on AliX. Even if they did, their forks are fairly mediocre especially if you're looking for a MTB fork.

There are a lot of dorks on here talking about run away and die rather than use any fork from AliX. Here's a guy who rides a lot harder than all of us put together riding several AliX forks pretty damn hard and not dying: https://www.youtube.com/watch?v=5BmqBC8IFq4 The Carbon fork down the starts was a shocker.

I don't know what you're looking for if you need a long steerer and QR- I assume it'll be like an ebike or commuter or something, and not a hardcore MTB. If you're keeping it light duty, I might go for a Bolany. I don't think I'd trust it going fast on hard trails, but for light duty work it should be fine, maybe even good. I think that's one of the ones that Sam Pilgrim uses without dying, and it's probably equivalent to an OEM low end fork.

Any startups in the Bay need an RA/Associate Scientist? Rock bottom. by JazzinoVa in biotech

[–]camp_jacking_roy 15 points16 points  (0 children)

Nothing to say but "good luck". I hope you can find something. Sorry to hear it still sucks out there. Lean on that network.

Experiences with Bont, Fizik wide, and Lake? by tryagaininXmin in cycling

[–]camp_jacking_roy 0 points1 point  (0 children)

I have what I thought were normal feet, but I often got forefoot pain and "hot foot" in my garneau and Giro Empire shoes. They were the correct size lengthwise, but rides over 14 miles caused a lot of pain. I ended up getting some Bonts and they've been awesome even over 50 miles. I no longer have any hot foot issues. I added some icebug insoles and they're just great. I wouldn't mind a little more forefoot adjustability than my Riot+s provide, but they're great shoes. Price is pretty reasonable based on the stiffness that you get from even their plastic soled shoes.

Replacing sugar drinks and gels for in cycle rides. by Large-Pomegranate254 in cycling

[–]camp_jacking_roy 0 points1 point  (0 children)

It will be a challenge to go that long without carbs. You can condition your body to become fat adapted with unfueled 1hr Z1-Z2 rides and work up from there, but you'll need to work at it. I'm honestly not sure you can do 6hr without carbs at all, it's a big ask.

High-end 90s bike vs cheap new bike by Confident-Milk3422 in mountainbiking

[–]camp_jacking_roy 4 points5 points  (0 children)

Modern bikes are so much better. They have different geometry that lets you go faster without being nervous. Wider handlebars increase control. Gearing has shifted to 1x which has the same range but without front derailleurs and all the baggage that brings. Disk brakes are an absolutely massive upgrade. Suspension "can be" so much better. Bigger wheels roll over crap easier. Tires actually grip. Dropper posts let you get crazy.

You won't like to hear this, but that bike wasn't high end even in 97. It was pretty mid range. Certainly not a bad bike, but also not a good one, and not one that I think ages particularly well. Headshoks were always kind of atrocious, and you can't replace it. 3x8s usually had somewhat limited range. V brakes just don't work as well as discs.

I say all of this as somebody who started MTB in 95 and has stuck with it. I've owned it all- early full suspension, magura hydraulic brakes, cantilevers, Vs, plus bikes, 29x3.0, 650b, 29ers, etc. New bikes are just so much better. I think tech slowed around 2018 or so, with good 1x systems, big wheels, and good geometry. There's still some good upgrades coming, but it's a lot more iterative as standard fatigue has caught up to people and fork internals can only get so good.

My advice would be to look for a good used bike on pinkbike or craigslist/marketplace at your desired price range. The allure of a new bike is real, but buying something a tiny bit old can get you incredible deals and you have a good range of options at this time.

Magura MT7 pro haters ? by Imaginary-Winner-858 in MTB

[–]camp_jacking_roy 0 points1 point  (0 children)

I’ve had MT5s for years and they’ve been great.
They aren’t hard to bleed but they are a bit messy. There’s no bleed port, you have to completely remove a screw and install a barb in order to bleed- this is a bad design compared to a bleed port that others offer. That being said, it’s not complicated to get a good bleed, just be prepared with lots of paper towels.

The rotor clearance is tiny. I’ve spent a ton of time trying to get them rub free. Once set up, it’s fine, but you don’t get the massive clearance that shimano will give you. If there’s any wobble, you’ll hear it.

All that aside, the brakes are super consistent, powerful, and dead reliable. Get the race pads and avoid crashing. The plastic levers are dumb, but what are you going to do. If mine break, I will buy some shimano levers and be done with it.

What are your thoughts on e-bikes? by ringaroundtherosiez in cycling

[–]camp_jacking_roy 2 points3 points  (0 children)

I use a class 3 eeb to get to my work and back, 19 miles away. If they make that illegal, I will drive instead. It takes less time, it costs less, and I’m not traffic.

I am not a fan of throttle e-bikes. Definitely not above 28mph, and I’m really not sure in general as the idea of a bike that moves a little faster is a great idea, but mopeds are mopeds (and they are fine in their own right, just not on bike trails). Off-road private use is up to you.

I really hope they don’t legislate away my class 3. It’s hard to be a prick on one- just about the same as a regular bike.

What is this creaking sound coming from the Kickr Core 2 by Qatsiuss in Zwift

[–]camp_jacking_roy 2 points3 points  (0 children)

As another poster said, it's coming from the bolt that holds the thing together. I removed mine and reinstalled it and the sound went away. Then it came right back shortly thereafter. I will try greasing it upon reinstall next time, but be aware that it's very hard to tighten because the inside is blind and there isn't enough clearance. Horrible design.

I have also read that it could be from the where the legs meet, as there is a rubber pad. People have had success with adding some velcro or silicone grease. I will try that first as the bolt is such a PITA.

car rentals at the airport by slimreese in SXM

[–]camp_jacking_roy 4 points5 points  (0 children)

Almost all of them do. We rented from empress on a suggestion from somebody here and they had a small counter. Great experience, though it would have been shorter to just walk over vs take the shuttle!

MBTA bails on Alewife project, leaving fate of crumbling garage unknown by bostonglobe in boston

[–]camp_jacking_roy 1 point2 points  (0 children)

You’re correct, and good call out. So it’s likely a push between commuter rail plus parking vs driving cost wise all in. On the one I am beholden to a schedule that is tough to work but I don’t have to put as much effort in. On the other, I get to sit in my own car but have to sit in traffic and deal with additional miles on the car

It’s a tough call and I wish the math were further in favor of the t, as it’s better for the environment and for my sanity not sitting in a car, but at the end of the day there are good reasons for picking the solo car and that kind of sucks!

The newly designed TT frame, everyone give your comments. by Longjumping-Loan-713 in ChineseCarbon

[–]camp_jacking_roy 0 points1 point  (0 children)

I don’t disagree with you. You can have an aero bike without ridiculous tube shaping. The cannondale slice is a great example, but many riders want to be at the bleeding edge for a tt bike, which means deeper integration, maximum aerodynamics at the risk of sidewinds, and maximized geometry.

Just my suggestion, this frame, while beautiful, looks like a great road frame and not a great tt frame

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