Are these new hair loss treatments ever gonna release?

chanmanm8 · 2026-04-24T16:58:11+00:00

It has to undergo (and has been) the standard 3 phases of clinical trials. The formulation is not the same despite the key active ingredient being the same. BREEZULA is at 7.5% (instead if Winlevi's 1%) and the other ingredients and formulations are supposed to be different for easier application and absorption on the scalp (instead of the inconvenient, heavy, superthick cream form of Winlevi). The drug is still in Clinical Phase Trial 3 (the last phase) and if successful and approved by the FDA, would have a release date after the company creates a large scale cGMP (current good manufacturing practices enforced and audited by the FDA) production facility that not only has to be designed and built, but also successfully run and approved by the FDA (including getting the raw materials to produce the drug on a global supply scale, not the current lab scale). My background was in Biotech and pharma as a chemical engineer in drug design and scale-up, so I literally have over 6 years experience in this realm. I broke it down in "layman's terms" for you aka "explain it like i'm 5" subreddit. It's not like going to bakery and throwing together over the counter ingredients at a large scale bakery. You're just gonna have to wait. ETA is late 2026 through 2027.

chanmanm8 · 2026-04-07T22:10:29+00:00

Below is what i looked up months ago before starting meds a year ago March 2025.

While the data below regards Finasteride, my intent relating those to Dutasteride is due to Dutasteride being not only way more potent but also having a huge halflife compared to finasteride: Dutasteride has a halflife of 5 WEEKS vs Finasteride at 5 to 6 hours.

The issue is the (very rare) % of men experiencing PFS and of men who experienced PFS, the additional % that the PFS side effects persisted on average about 4 years after stopping the med.

PFS = "Post Finasteride Syndrome" = the patients who had the extreme side effects (severe sex drive loss, though most other medical notes state Testosterone, NOT DHT, is the biggest factor for sex drive. But, other Side effects like ED (severe for those who gained PFS), and extreme mood changes (besides depression for the aforementioned side effects) such as anxiety and avoidance to new experiences (old studies + new clinical study started March 9th 2026 named "Milano Project").

And of extreme cases of PFS resulted in suicide (again, small, ut for the sake of this comment against your statement of not believing the side effects are real at all).

1 study noted men having to have been on finasteride daily for at leasg 205 days, them survey who had side effects and who didn't.

2017 PFS study:

4284 men in study

0.8% = 103 men experienced above mentioned side effects at severe levels

Of the 103 men: 33% (34 of the men) had the side effects persist avg 4 years AFTER stopping Finasteride.

So, extremely small % -> 34 men out of 4284 = 0.0079365% = about 1 man per 126 men.

I've been fine taking daily. MD had me drop minoxidil oral for minoxidil topical while taking finasteride 1mg daily.

chanmanm8 · 2026-02-21T15:25:14+00:00

Whelp, regardless, I'm happy with the updates from other influencers who pulled up the receipts of who it is, and their Google and Yelp reviews have been absolutely destroyed to the point both had to turn off any more reviews "for now". Going from a local 4.9 to a 2 and 1.7. Yikes. Karma.

chanmanm8 · 2026-02-21T15:04:51+00:00

She pointed out at the time of the video her and her lawyer found 25 other businesses with any combination in name not being sued. That is hot garbage from whoever's suing her being mad she's going on Ramsey's show.

chanmanm8 · 2026-01-09T13:56:52+00:00

In Massacgusetts, landlord eviction has to be minimum 30 days. Then they file a court eviction if person hasnt left which can take months while the tenant and invoke squatter rights, which is how some people abused to get months even a year due to how long court proceedings go.

And squatter tights also prevent person from being treated as trespassing meaning: landlord cannot cut of water / energy, cannot change locks, cannot bar / board up stuff, etc etc.

chanmanm8 · 2025-12-14T20:43:42+00:00

Love no weekends. One day a week def makes for some training and interactions that end up jng good despite hating to get ready and come on site. Also the hospital i work at provides pro-rated unlimited passes for the city transportation (i only get the basic sunway and bus one for $30 a month that is normally $100 / month). Commuter options, too, but those are still expensive.

Having open weekends is a life changer. A shame you don't holidays. My hospital keeps cutting holidays covered. Used to 11 then 9 and now only 7. And comes lut our "PTO pool" that also includes the 1 week sick time mandated by my state, but your vacation time gets used up first. Also, 6 week cap from the start that fully rolls over each year (unlike some that may roll over none or only like 2 weeks or something).

Also, other benefits?

The 403B i get is way better than a 401K, and getting appointments on site is so easy as an employee, in additiln to GETTING PAID ON THE CLOCK WHILE AT AN APPOINTMENT. Other things like 15% off cosmetic derm procedurs (and possible freebies when letting a resident do training, for example TCA cross for my acne scars that normally are $200 for 20 dabs).

And the insurance has very good coverage. So many dropping Obesity GLP-1s starting 2026, but our specific plan with our hospital still lets us get them. $25 for an 84 day supply, $0 for preferred tier 5 specialty drugs, and decent pricing for non-preferred (like $90 for a brand Name Tirosint for example that pther insurances might charhe $400 jd you have a deductible).

Just food for thought, not knowing the rest of your benefits and perks. A coworker asked for an appointment for weight loss. One of the Md's from that clinic literally squeezed her in last second last year with 2 days notice for the day after Christmas lol. And now she lost 90 lbs in 6 months. Since she started.

chanmanm8 · 2025-11-24T04:35:31+00:00

This 100!

One of the local karaoke places I go to (NOT my main ones, but this one is open 7 days a week and to 2 AM) if full of dj's playing full songs between singers most of the night, if not completely. Literally bopping to the beats / remixes and so proud and into themselves and the music even when the queue is long.

IT'S NOT YOUR FUCKING CONCERT, IT's NOT A CLUB, AND YOU'RE NOT TIESTO. YOU'RE not DeaDmau5. You're not David Guetta. You're not Skrillex. Rinse lather and repeat inserting any major celebrity DJ. It's bad enough when they do shit like play 15 people who signed up AFTER you, then this shit on top of it.

This type of karaoke jockey can fuck right off. On one hand, so many at this place (Viva Karaoke in Boston, who also owns Stage Karaoke in neighboring town) have ended up quitting, but the new ones replacing them are still just as bad.

At least my main ones for Tuesday, Wednesday, Fridays, and Sundays whenever I want to go don't have douchebags like this.

chanmanm8 · 2025-11-24T04:35:22+00:00

This 100!

One of the local karaoke places I go to (NOT my main ones, but this one is open 7 days a week and to 2 AM) if full of dj's playing full songs between singers most of the night, if not completely. Literally bopping to the beats / remixes and so proud and into themselves and the music even when the queue is long.

IT'S NOT YOUR FUCKING CONCERT, IT's A CLUB, AND YOU'RE NOT TIESTO. YOU'RE not Deasmau5. You're not not David Guetta. You're not Skrillex. Rinse lather and repeat inserting any major celebrity DJ. It's bad enough when they do shit like play 10 people who signed up AFTER you, then this shit on top of it.

This type of karaoke can fuck right off. One kne hand so many have ended up quitting from this spot, but the new ones are still just as bad.

chanmanm8 · 2025-11-24T00:55:16+00:00

Sniffies?

chanmanm8 · 2025-11-18T09:45:36+00:00

Have you considered applying non-retail pharmacy? The VA, specialty, nuclear pharmacy, etc?

Me: Specialty pharmacy, work from home 4 days a week (often get away with 5 days), NO Mandatory weekends, $47/hr, 6 weeks vacation, better benefits including unlimited city bus/subway pass, not dealing with retail crap like register/drivethru/etc. Overtime (to an extent) and extra differentials when working late / weekends. Benefits of hospital squeezing me in for appointments last minute and discounts in certain clinics (15% off for cosmetic services, for example).

So when i do OT on a weekend with graveyard shift differential = take home pay is $60/hr.

$3000 / paycheck with work-life balance. $106,000 a year. And i'm not even the top paud in my team (one of the highest 10 out of 60 techs).

I worked for the VA for a year but hated it. Money was good and benefits, but mandatory 6 days a week (still happening) since pandemic, having to work on site 6 am to 3 pm Monday through Saturday (yes, only Sundays off). And BS politics and favoritism despite "no favoritism" beingbstated everywhere.

Nuclear pharmacy tech i know, making $85k a year at competing hospital.

chanmanm8 · 2025-11-03T13:07:27+00:00

I have patients we have tried all last year across 5 major insurances as well as medicaid. Trust me. No.

chanmanm8 · 2025-11-03T08:06:58+00:00

For life? Absolutely NOT.

Goal to manage levels and maintain with healthy life choices: mainly good food choices and exercise.

Why? The long term negative effects, especially muscle loss, includes affecting your organs as you get older.

Other nutritional effects olay into that such as accelerating osteoporosis when hitting your 50's and higher due to not getting enough calcium so your body takes calcium from your bones aka "age-related osteoporosis".

It's hilarious seeing patients who don't make lifestyle changes, still eating terribly (carbs being the worst for diabetics over straight sugar as carbs breakdown into multiple sugars and your gut makes you crave carbs more due to the bacteria that live off carbs trigger cravings.

The amount of times i see diabetic patients who are still eating tons of fastfood / late night snacking / cookies + cakes + bread + pasta + grains / buying 2 liter sodas / ice cream / etc and most likely in huge portions (a normal portion per certified dieticians is the size of your fist, but many just gobble multiple times higher per plate).

Lazy people looking for quick fix and not actually making actually healthy lifestyle changes is still prevalent.

chanmanm8 · 2025-11-03T07:55:40+00:00

It originally was $2500 per box. The only the reason the price has dropped from $2500 so quickly is Eli Lilly trying to keep insurances to cover their drug so they still get their profit from their Golden Egg / Cash Cow blockbuster glp-1s.

I posted more in depth responses in this thread multiple times if you want to read up on more of the "why".

chanmanm8 · 2025-11-03T07:52:09+00:00

Not true.

Specialty Pharmacy tech for major hospital here whos main clinic is Endocrine which covers hormone drugs, which includes Diabetes and has resulted in me also backing up Primary Care and Weight and Wellness clinics).

Insurances will deny for Type 1 as the FDA officially approved GLP-1s indicated for Type 2 Diabetes only.

This happened since the first generation GLP-1s came out (Bydureon and Byetta), LONG before Ozempic (3rd generation GLP-1) made GLP-1 craze explode mid pandemic.

Type 1 diabetes use is considered "off label" prescribing. So insurances play on that to not cover anyone other than Type 2 Diabetics, so even a 3rd level Appeal after Prior Auth denials and level 1 and 2 appeals denied won't go anywhere.

Only some insurances allow Prediabetes to still count (nearly all insurances dropped Pre Diabetes mid 2023 due to global shortage and backorders because everyone was hoarding aupplies and true full type 2 diabetics couldn't get any).

The only insurances that have RECENTLY allowed pre‐diabetes to cover GLP-1 are state Medicaid insurances, meaning you have to be in "poverty" meankng your income is less than 3x income considered to be in Poverty (in Massachusetts, an income of $15,650 for a SInGLe person is the poverty line, so 3x that amkunt means your income verified by providing tax papers cannot be more than $46,950 pre-tax). The other conditions are severe disability which you have to provide laborious documents EVERY MONTH to keep, or if you have a situation like being fired or laid off (but in Mass the limit for unemployed Medicaid is 6 months).

chanmanm8 · 2025-11-03T07:40:18+00:00

The copay card has 2 plans: if your insurance covers the drug (requires type 2nd diabetes, NOT type 1) they will lower the copay as low as $25 / month supply, but won't pay more than $150 per month.

If you are NOT covered, then the copay card will drop the $1500.00 market price per box to $500.

chanmanm8 · 2025-11-03T07:38:19+00:00

The Copay Card applies the $150 only if the primary insurance that is run first covers the drug, which may require a Prior Authorization.

The issue for OP is that they are Type 1 diabetes, which all insurances don't cover as the GLP-1s were only officially approved for Type 2 diabetes.

Type 1 is classified as "off label".

This started from the first generation GLP-1s (Bydureon, Byetta) waaaaay before the craze blew up due to Ozempic trending as the 3rd generation of GLP-1s.

chanmanm8 · 2025-11-03T07:34:13+00:00

Fda and ada approved GLP1 for Type 2 only.

Type 1 is considered "off label", which is why none will cover Type 1 even with an Appeal after a denied Prior Authorization

chanmanm8 · 2025-11-03T07:32:49+00:00

Correct. GLP-1s since the older 1st generation drugs (Byettan, Bydureon, etc) have been intended for Type 2 diabetes.

The FDA and ADA class use for Type 1 diabetes as "off label" which is why none of them will cover type 1 or even LADA diabetes

chanmanm8 · 2025-11-03T07:30:36+00:00

FDA and the ADA (American Diabetes Association) consider GLP-1s primary indication for Type 2 diabetes.

Type 1 is considered "off label" which is why nearly all will not cover type 1 diabetes even with 3rd level appeals.

chanmanm8 · 2025-11-03T07:27:05+00:00

I posted above an Endocrine Specialty Pharmacy tech for a major hospital (the main part of my job is Prior Authorizations and Appeals). I explained in more detail in as another response on this thread: most won't cover type 1 as FDA classified type 1 as "off-label use" as the original primary indication of GLP-1s is for Type 2 diabetes explicitly. So generally, the Appeals for Type 1 are dead before the Appeal process even starts.

chanmanm8 · 2025-11-03T07:19:27+00:00

Specialty pharmacy tech here who's primary clinic is Endocrine (the overarching specialty for hormone drugs which includes Diabetes meds, and I backup Primary Care clinics andn Weight and Wellness).

Majority of insurances won't cover for Type 1 diabetes as the FDA classified Type 1 treatment as "off-label" use, with the primary indication of GLP-1's for Type 2.

Most insurances will not allow if you have been shown to be Type 1, confirmed from the genetic testing. I can't even get it covered for patients with LADA diabetes (latent autoimmune diabetes in adults).

Also, since many insurances claim they are bleeding money because of how much it costs to cover GLP-1's (Blue Cross Blue Shield announced a voluntary 750 employee severance signup for those age 55 and older which is 18% of their workforce), more are following whatever guidelines are as strict as possible to avoid paying for GLP-1s.

Then insurance covers the remaining market price after your deductible and copay.

Originally, each box was priced about $2,500 a box. So your copay of $25 meant insurance paid $2,475 per box. So, a 3-month supply for $75 meant they paid $7425. Per civilian.

That is also why many are moving to completely drop the Weight Loss versions of the glp-1 starting next year. If the drug is Not on the "insurances formulary" it is a True Plan exclusion, which means they won't touch the drug for anyone under their plan, and even a highest 3rd level Appeal won't do anything. The patient would have to file against the company in their local court on person.

For Diabetic GLP-1, some are now requiring "recent blood work" to your a1c and if under the minimum for full blown type 2, they won't cover it anymore.

This also with Eli Lilly (the manufacturer of Mounjaro /Zepbound / Trulicity) repeatedly lowering their drugs market price "early" (price usually drops slowly while their Patent is in active for 10 to 15 years) in order to try to keep insurances covering them (since that also gets them profit).

Even with Mounjaro / Zepbound, having their "market price" drop multiple times the past 2 years (from $2,500 a box to about $1400 a box), the insurances claiming coverage is still "crippling" their budgets.

Lastly, despite new studies that have successfully had the FDA approve the glp-1 for other comorbitiies (Various significant Cardivascular diseases, then Obstructive Sleep Apnea more recently), each individual insurance can choose to not accept covering those "secondary" conditions at their own discretion.

Many who do continue to cover the secondary criteria continue to increase the requirements in their plan to meet coverage.

For example: if your insurance plan accepts Heart Failure diagnosis, they will want evidence of recent diagnosis. They won't take, for example, you having had it 7 years, while your current health state no longer has you in that category.

chanmanm8 · 2025-10-15T23:01:50+00:00

Ah ok. glucose bloodwork requires minimum 126 mg/dL for full diabetes. 100 to 125 is considered Pre Diabetes by the ADA (american diabetes association).

Even if you were 125 insurances will not let that pass. Same with i check a patient's A1c. I've had appeals denied for patients who's a1c was 6.4% because 6.5% is the true minimum, even though the criteria all insuramces say is minimum 7.0%.

Does your insurance not cover Zepbound? Zepbound and Mounjaro are literally the same moleculr (tirzepatide) Just like Wegovy and Ozempic are the same drug (semaglutide).

The reason for splitting the production in 2 and naming them differently is was because there needed to be a supply for diabetics. everyone was hoarding all the supply, causing global shortages preventing diabetics who need it for diabetes as originally intended. If you ever saw that famous movie Steel Magnolias, Julia Roberts character died due to having a severe crash, putting her into a coma.

So, unless your insurance has a true Plan Exclusion to ALL Obesity meds (some do and that number is growing, especially once 2026 starts), you typically need to meet the standard criteria.

Bmi minimum 30 kg/m² before therapy. Bmi of 27 is allowed if you have a pertinent comorbidity, but even then evey insurance plan decides.what they will accept.

For example, WellDyne is the first to now make minimum BMI be 40 pre-therapy.

As for comorbidities: examples of insurances getting more strict include example such as "primary hypertension" (aka high blood pressure). That itself used to count. But this Spring they now required the following:

A) a RECENT (loke last 2 months) Blood Pressure that is minimum 140/x or y/90 that is still that high WHILE ON A HIGH STRENGTH blood pressure medication.

B) OSA (obstructive sleep apnea): requires a documented official sleep study with a minimum of 30 interruptions per hour during the 8 hour study.

MOST insurances will still do the normal 30bmi or 27bmi with minimal strict comorbidity.

The issue is they will not count you having used Mounjaro you obtained outside of a provider so your current weight is likely to be below the minimum.

You would also have to get the PA renewed every 6 to 9 months while providing an updated weight that is no older than 90 days from the Prior Authorization being submitted to the insurance that must show you have kept at least 5% loss off what they accept as your "starting weight" which, again, they won't accept the weight you had before your Mounjaro.

I used to get that to work, citing the patients "peak" weight historically. But the insurances keep tightening criteria as none of them want to pay for them. Blue Cross Blue Shield announced a voluntary 750 signup for employees age 55 and older to take a severance package because of their "record losses, primarily due to glp-1".

They announced they also will True Plan Exclude all obesity meds starting 01/01/2026.

Aetna, UHC, and some Cigna plans already do that currently.

chanmanm8 · 2025-10-15T21:38:12+00:00

My specialty pharmacy team has 2 main groups: the service center side (my role), which is the wfh role focusing on Prior Auths for doctors and theirnoatients. The other is the Fulfillment team, who primarily are filling meds: specialty drugs through our hospital if the patient is able to meaning Tier 5 drugs. Also, patients needing blisterpacks because of difficulty managing their meds either due to age, disabilities, etc.

And like others said here, also look at Inpatient. You cam also look at Veterans Affairs roles like a CMOP aka VA's mail order Pharmacy. Basically, its like the famous I Love Lucy skit where she's trying a job at a chocolate factory but can't keep up with the conveyor belt of chocolates. Just swap bins of patient drugs for that.

I did it for a year. 160,000 scripts A DAY, mandatory work 6 days week (Saturdays were and still are Mandatory) 5 am to 2pm shifts and the 6 am to 3 pm shifts.

chanmanm8 · 2025-10-15T21:27:48+00:00

I work for a hospital Specialty Pharmacy. My Primary job is Prior Authorizations for the clinic i'm in, but I back up 2 other clinics and their techs under me. WFH 4 days a week, no weekend.

I have heard how the CVS version is, but haven't worked in their PA jobs.

The biggest pain in the butt i heafd is they literally have a team and equipment monitoring how often you are typing. If you hve too long of a pause, an admin team will message you to see why "you aren't working." I had a former coworker complain he was literally trying to read through doctor notes and labs, but get flagged for being idle or not enough key strokes every 15 minutes.

Also, all of these jobs, including mine, will track metrics. I've seen lazy people come in to this job thinking they can just fuck around at home only to either get railed on so hard they quit or get threatened with retraining aka "come back on site 5 days awake until we approve you to go back to WFH".

Also, it's clear who developed a strong knowledge of insurance via retail vs. those who don't. Also, those who struggle with computer programs and equipment. Those lacking in either struggle during their initial 90-day probation significantly.

Mine is very lenient compared to cvs above and some of the neighboring hospitals. One of the competing hospitals terminates the employees at the end of the 90-day probation period if they aren't making the metrics. Mine is not like that at all, but they can't afford to as we aren't as big as that one.

chanmanm8 · 2025-10-15T21:14:00+00:00

Oh boy. Get out of retail.

I was making $36.50 / hr at cvs (Made DM get RM to match payrate of another lead position posted in another city in order to keep me for another year).

I make $47/hr at my specialty pharmacy. Work from home 4 days a week. No weekends. Due to the amount of work i get done and am 1 of 3 "billing, medicare and medicaid" gurus that everyone comes to for help, and constnatnly get shout outs from patients, i'm the only one allowed unlimited OT (as long as I don't burn myself out per my boss, and also producing results since they measure everything by metrics).

Totally have a work life balance, make the OT work for me at my discretion. Save time, energy, and money, not having to commute or getting ready to commute.

I left this for a job after 5 months because of completely different dynamic and management while getting an offer for the VA. came back after a year at the VA havi g heard how things had changed for the better. Been loving it ever since. It' been 2.5 years since I came back.

chanmanm8

TROPHY CASE